Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7U6F

Mouse retromer (VPS26/VPS35/VPS29) heterotrimers

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
B30005515molecular_functionprotein binding
B30005737cellular_componentcytoplasm
B30005764cellular_componentlysosome
B30005768cellular_componentendosome
B30005769cellular_componentearly endosome
B30005829cellular_componentcytosol
B30006886biological_processintracellular protein transport
B30010008cellular_componentendosome membrane
B30015031biological_processprotein transport
B30016020cellular_componentmembrane
B30030904cellular_componentretromer complex
B30030906cellular_componentretromer, cargo-selective complex
B30031982cellular_componentvesicle
B30032456biological_processendocytic recycling
B30042147biological_processretrograde transport, endosome to Golgi
B30097422cellular_componenttubular endosome
B40005515molecular_functionprotein binding
B40005737cellular_componentcytoplasm
B40005768cellular_componentendosome
B40005829cellular_componentcytosol
B40006886biological_processintracellular protein transport
B40006896biological_processGolgi to vacuole transport
B40010008cellular_componentendosome membrane
B40015031biological_processprotein transport
B40016020cellular_componentmembrane
B40030904cellular_componentretromer complex
B40030906cellular_componentretromer, cargo-selective complex
B40032456biological_processendocytic recycling
B40042147biological_processretrograde transport, endosome to Golgi
B40043231cellular_componentintracellular membrane-bounded organelle
B40046872molecular_functionmetal ion binding
D10005515molecular_functionprotein binding
D10005737cellular_componentcytoplasm
D10005739cellular_componentmitochondrion
D10005764cellular_componentlysosome
D10005768cellular_componentendosome
D10005769cellular_componentearly endosome
D10005770cellular_componentlate endosome
D10005829cellular_componentcytosol
D10006624biological_processvacuolar protein processing
D10006886biological_processintracellular protein transport
D10007040biological_processlysosome organization
D10010008cellular_componentendosome membrane
D10010628biological_processpositive regulation of gene expression
D10010629biological_processnegative regulation of gene expression
D10010821biological_processregulation of mitochondrion organization
D10014069cellular_componentpostsynaptic density
D10015031biological_processprotein transport
D10016020cellular_componentmembrane
D10030904cellular_componentretromer complex
D10030906cellular_componentretromer, cargo-selective complex
D10031647biological_processregulation of protein stability
D10031648biological_processprotein destabilization
D10031748molecular_functionD1 dopamine receptor binding
D10032456biological_processendocytic recycling
D10032463biological_processnegative regulation of protein homooligomerization
D10033365biological_processprotein localization to organelle
D10036010biological_processprotein localization to endosome
D10042147biological_processretrograde transport, endosome to Golgi
D10043005cellular_componentneuron projection
D10043025cellular_componentneuronal cell body
D10043653biological_processmitochondrial fragmentation involved in apoptotic process
D10045056biological_processtranscytosis
D10045202cellular_componentsynapse
D10045732biological_processpositive regulation of protein catabolic process
D10048471cellular_componentperinuclear region of cytoplasm
D10050728biological_processnegative regulation of inflammatory response
D10050804biological_processmodulation of chemical synaptic transmission
D10050882biological_processvoluntary musculoskeletal movement
D10051246biological_processregulation of protein metabolic process
D10060161biological_processpositive regulation of dopamine receptor signaling pathway
D10061357biological_processpositive regulation of Wnt protein secretion
D10090128biological_processregulation of synapse maturation
D10090141biological_processpositive regulation of mitochondrial fission
D10090263biological_processpositive regulation of canonical Wnt signaling pathway
D10090326biological_processpositive regulation of locomotion involved in locomotory behavior
D10097422cellular_componenttubular endosome
D10098691cellular_componentdopaminergic synapse
D10098793cellular_componentpresynapse
D10098794cellular_componentpostsynapse
D10098887biological_processneurotransmitter receptor transport, endosome to postsynaptic membrane
D10098978cellular_componentglutamatergic synapse
D10099003biological_processvesicle-mediated transport in synapse
D10099073cellular_componentmitochondrion-derived vesicle
D10099074biological_processmitochondrion to lysosome vesicle-mediated transport
D10099639biological_processneurotransmitter receptor transport, endosome to plasma membrane
D10150052biological_processregulation of postsynapse assembly
D11902823biological_processnegative regulation of late endosome to lysosome transport
D11902950biological_processregulation of dendritic spine maintenance
D11903181biological_processpositive regulation of dopamine biosynthetic process
D11903828biological_processnegative regulation of protein localization
D11904377biological_processpositive regulation of protein localization to cell periphery
D11905166biological_processnegative regulation of lysosomal protein catabolic process
D12000331biological_processregulation of terminal button organization
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues7
DetailsBINDING:
ChainResidueDetails
B4ASP8
B4HIS10
B4ASN39
B4ASP62
B4HIS86
B4HIS115
B4HIS117

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9UBQ0
ChainResidueDetails
B4LYS50

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:17947660, ECO:0007744|PubMed:19131326
ChainResidueDetails
D1TYR791

220113

PDB entries from 2024-05-22

PDB statisticsPDBj update infoContact PDBjnumon