7U5S

CryoEM structure of the Candida albicans Aro1 dimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0003855	molecular_function	3-dehydroquinate dehydratase activity
A	0003856	molecular_function	3-dehydroquinate synthase activity
A	0003866	molecular_function	3-phosphoshikimate 1-carboxyvinyltransferase activity
A	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
A	0004765	molecular_function	shikimate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0009073	biological_process	aromatic amino acid biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0015801	biological_process	aromatic amino acid transport
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0046872	molecular_function	metal ion binding
A	0071466	biological_process	cellular response to xenobiotic stimulus
B	0003824	molecular_function	catalytic activity
B	0003855	molecular_function	3-dehydroquinate dehydratase activity
B	0003856	molecular_function	3-dehydroquinate synthase activity
B	0003866	molecular_function	3-phosphoshikimate 1-carboxyvinyltransferase activity
B	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
B	0004765	molecular_function	shikimate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0009073	biological_process	aromatic amino acid biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0015801	biological_process	aromatic amino acid transport
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0046872	molecular_function	metal ion binding
B	0071466	biological_process	cellular response to xenobiotic stimulus

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	418
Details	Region: {"description":"3-dehydroquinase"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton acceptor; for 3-dehydroquinate synthase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---