7U4S

Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006006	biological_process	glucose metabolic process
A	0006096	biological_process	glycolytic process
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0030312	cellular_component	external encapsulating structure
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
A	0071555	biological_process	cell wall organization
B	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006006	biological_process	glucose metabolic process
B	0006096	biological_process	glycolytic process
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0030312	cellular_component	external encapsulating structure
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding
B	0071555	biological_process	cell wall organization
C	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006006	biological_process	glucose metabolic process
C	0006096	biological_process	glycolytic process
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0030312	cellular_component	external encapsulating structure
C	0050661	molecular_function	NADP binding
C	0051287	molecular_function	NAD binding
C	0071555	biological_process	cell wall organization
D	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006006	biological_process	glucose metabolic process
D	0006096	biological_process	glycolytic process
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0030312	cellular_component	external encapsulating structure
D	0050661	molecular_function	NADP binding
D	0051287	molecular_function	NAD binding
D	0071555	biological_process	cell wall organization

Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
A	ALA149-LEU156

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10009

Chain	Residue	Details
A	OCS151
B	OCS151
C	OCS151
D	OCS151

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site_id	SWS_FT_FI2
Number of Residues	32
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ARG12
B	ASP34
B	ARG79
B	SER150
B	THR181
B	THR210
B	ARG233
B	ASN315
C	ARG12
C	ASP34
C	ARG79
A	ASP34
C	SER150
C	THR181
C	THR210
C	ARG233
C	ASN315
D	ARG12
D	ASP34
D	ARG79
D	SER150
D	THR181
A	ARG79
D	THR210
D	ARG233
D	ASN315
A	SER150
A	THR181
A	THR210
A	ARG233
A	ASN315
B	ARG12

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site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Activates thiol group during catalysis => ECO:0000250

Chain	Residue	Details
A	HIS178
B	HIS178
C	HIS178
D	HIS178

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