7U1U
Crystal structure of arabidopsis thaliana acetohydroxyacid synthase W574L mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003984 | molecular_function | acetolactate synthase activity |
| A | 0009082 | biological_process | branched-chain amino acid biosynthetic process |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PROSITE/UniProt
| site_id | PS00187 |
| Number of Residues | 20 |
| Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. IGasvanPdaivVdIdGDGS |
| Chain | Residue | Details |
| A | ILE521-SER540 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16407096 |
| Chain | Residue | Details |
| A | ASP414 | |
| A | GLU144 | |
| A | GLN207 | |
| A | ARG246 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:32640464, ECO:0007744|PDB:6U9H |
| Chain | Residue | Details |
| A | GLN487 | |
| A | SER186 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16407096, ECO:0007744|PDB:1Z8N |
| Chain | Residue | Details |
| A | LYS220 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16407096, ECO:0007744|PDB:1YBH |
| Chain | Residue | Details |
| A | LEU574 | |
| A | SER653 | |
| A | LYS256 | |
| A | ASP376 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16407096, ECO:0000269|PubMed:32640464, ECO:0007744|PDB:6U9H |
| Chain | Residue | Details |
| A | GLY371 | |
| A | ASP395 | |
| A | GLY508 | |
| A | GLY308 | |
| A | THR331 | |
| A | LEU349 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:32640464, ECO:0007744|PDB:6VZ8 |
| Chain | Residue | Details |
| A | GLY511 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16407096, ECO:0000269|PubMed:19187232, ECO:0000269|PubMed:32640464, ECO:0007744|PDB:6U9H |
| Chain | Residue | Details |
| A | ASP538 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16407096, ECO:0000269|PubMed:19187232 |
| Chain | Residue | Details |
| A | ASN565 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16407096, ECO:0000269|PubMed:19187232, ECO:0000269|PubMed:32640464, ECO:0007744|PDB:6VZ8 |
| Chain | Residue | Details |
| A | HIS567 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | MOD_RES: Cysteine sulfinic acid (-SO2H) => ECO:0000269|PubMed:16407096, ECO:0000269|PubMed:19187232 |
| Chain | Residue | Details |
| A | CSD340 |
