7TKR

Yeast ATP synthase State 3catalytic(d) with 10 mM ATP backbone model

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0005739	cellular_component	mitochondrion
0	0005743	cellular_component	mitochondrial inner membrane
0	0005758	cellular_component	mitochondrial intermembrane space
0	0005829	cellular_component	cytosol
0	0006811	biological_process	monoatomic ion transport
0	0008289	molecular_function	lipid binding
0	0015078	molecular_function	proton transmembrane transporter activity
0	0015986	biological_process	proton motive force-driven ATP synthesis
0	0016887	molecular_function	ATP hydrolysis activity
0	0031966	cellular_component	mitochondrial membrane
0	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
0	0042802	molecular_function	identical protein binding
0	0045259	cellular_component	proton-transporting ATP synthase complex
0	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
0	1902600	biological_process	proton transmembrane transport
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0005758	cellular_component	mitochondrial intermembrane space
1	0005829	cellular_component	cytosol
1	0006811	biological_process	monoatomic ion transport
1	0008289	molecular_function	lipid binding
1	0015078	molecular_function	proton transmembrane transporter activity
1	0015986	biological_process	proton motive force-driven ATP synthesis
1	0016887	molecular_function	ATP hydrolysis activity
1	0031966	cellular_component	mitochondrial membrane
1	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
1	0042802	molecular_function	identical protein binding
1	0045259	cellular_component	proton-transporting ATP synthase complex
1	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
1	1902600	biological_process	proton transmembrane transport
2	0005739	cellular_component	mitochondrion
2	0005743	cellular_component	mitochondrial inner membrane
2	0005758	cellular_component	mitochondrial intermembrane space
2	0005829	cellular_component	cytosol
2	0006811	biological_process	monoatomic ion transport
2	0008289	molecular_function	lipid binding
2	0015078	molecular_function	proton transmembrane transporter activity
2	0015986	biological_process	proton motive force-driven ATP synthesis
2	0016887	molecular_function	ATP hydrolysis activity
2	0031966	cellular_component	mitochondrial membrane
2	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
2	0042802	molecular_function	identical protein binding
2	0045259	cellular_component	proton-transporting ATP synthase complex
2	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
2	1902600	biological_process	proton transmembrane transport
3	0005739	cellular_component	mitochondrion
3	0005743	cellular_component	mitochondrial inner membrane
3	0005758	cellular_component	mitochondrial intermembrane space
3	0005829	cellular_component	cytosol
3	0006811	biological_process	monoatomic ion transport
3	0008289	molecular_function	lipid binding
3	0015078	molecular_function	proton transmembrane transporter activity
3	0015986	biological_process	proton motive force-driven ATP synthesis
3	0016887	molecular_function	ATP hydrolysis activity
3	0031966	cellular_component	mitochondrial membrane
3	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
3	0042802	molecular_function	identical protein binding
3	0045259	cellular_component	proton-transporting ATP synthase complex
3	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
3	1902600	biological_process	proton transmembrane transport
4	0005739	cellular_component	mitochondrion
4	0005743	cellular_component	mitochondrial inner membrane
4	0005758	cellular_component	mitochondrial intermembrane space
4	0005829	cellular_component	cytosol
4	0006811	biological_process	monoatomic ion transport
4	0008289	molecular_function	lipid binding
4	0015078	molecular_function	proton transmembrane transporter activity
4	0015986	biological_process	proton motive force-driven ATP synthesis
4	0016887	molecular_function	ATP hydrolysis activity
4	0031966	cellular_component	mitochondrial membrane
4	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
4	0042802	molecular_function	identical protein binding
4	0045259	cellular_component	proton-transporting ATP synthase complex
4	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
4	1902600	biological_process	proton transmembrane transport
5	0005739	cellular_component	mitochondrion
5	0005743	cellular_component	mitochondrial inner membrane
5	0005758	cellular_component	mitochondrial intermembrane space
5	0005829	cellular_component	cytosol
5	0006811	biological_process	monoatomic ion transport
5	0008289	molecular_function	lipid binding
5	0015078	molecular_function	proton transmembrane transporter activity
5	0015986	biological_process	proton motive force-driven ATP synthesis
5	0016887	molecular_function	ATP hydrolysis activity
5	0031966	cellular_component	mitochondrial membrane
5	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
5	0042802	molecular_function	identical protein binding
5	0045259	cellular_component	proton-transporting ATP synthase complex
5	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
5	1902600	biological_process	proton transmembrane transport
6	0005739	cellular_component	mitochondrion
6	0005743	cellular_component	mitochondrial inner membrane
6	0005758	cellular_component	mitochondrial intermembrane space
6	0005829	cellular_component	cytosol
6	0006811	biological_process	monoatomic ion transport
6	0008289	molecular_function	lipid binding
6	0015078	molecular_function	proton transmembrane transporter activity
6	0015986	biological_process	proton motive force-driven ATP synthesis
6	0016887	molecular_function	ATP hydrolysis activity
6	0031966	cellular_component	mitochondrial membrane
6	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
6	0042802	molecular_function	identical protein binding
6	0045259	cellular_component	proton-transporting ATP synthase complex
6	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
6	1902600	biological_process	proton transmembrane transport
7	0005739	cellular_component	mitochondrion
7	0005743	cellular_component	mitochondrial inner membrane
7	0005758	cellular_component	mitochondrial intermembrane space
7	0005829	cellular_component	cytosol
7	0006811	biological_process	monoatomic ion transport
7	0008289	molecular_function	lipid binding
7	0015078	molecular_function	proton transmembrane transporter activity
7	0015986	biological_process	proton motive force-driven ATP synthesis
7	0016887	molecular_function	ATP hydrolysis activity
7	0031966	cellular_component	mitochondrial membrane
7	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
7	0042802	molecular_function	identical protein binding
7	0045259	cellular_component	proton-transporting ATP synthase complex
7	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
7	1902600	biological_process	proton transmembrane transport
8	0005739	cellular_component	mitochondrion
8	0005743	cellular_component	mitochondrial inner membrane
8	0005758	cellular_component	mitochondrial intermembrane space
8	0005829	cellular_component	cytosol
8	0006811	biological_process	monoatomic ion transport
8	0008289	molecular_function	lipid binding
8	0015078	molecular_function	proton transmembrane transporter activity
8	0015986	biological_process	proton motive force-driven ATP synthesis
8	0016887	molecular_function	ATP hydrolysis activity
8	0031966	cellular_component	mitochondrial membrane
8	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
8	0042802	molecular_function	identical protein binding
8	0045259	cellular_component	proton-transporting ATP synthase complex
8	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
8	1902600	biological_process	proton transmembrane transport
9	0005739	cellular_component	mitochondrion
9	0005743	cellular_component	mitochondrial inner membrane
9	0005758	cellular_component	mitochondrial intermembrane space
9	0005829	cellular_component	cytosol
9	0006811	biological_process	monoatomic ion transport
9	0008289	molecular_function	lipid binding
9	0015078	molecular_function	proton transmembrane transporter activity
9	0015986	biological_process	proton motive force-driven ATP synthesis
9	0016887	molecular_function	ATP hydrolysis activity
9	0031966	cellular_component	mitochondrial membrane
9	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
9	0042802	molecular_function	identical protein binding
9	0045259	cellular_component	proton-transporting ATP synthase complex
9	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
9	1902600	biological_process	proton transmembrane transport
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005829	cellular_component	cytosol
A	0006754	biological_process	ATP biosynthetic process
A	0006811	biological_process	monoatomic ion transport
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0016887	molecular_function	ATP hydrolysis activity
A	0032559	molecular_function	adenyl ribonucleotide binding
A	0042645	cellular_component	mitochondrial nucleoid
A	0043531	molecular_function	ADP binding
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0046034	biological_process	ATP metabolic process
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005758	cellular_component	mitochondrial intermembrane space
B	0005829	cellular_component	cytosol
B	0006754	biological_process	ATP biosynthetic process
B	0006811	biological_process	monoatomic ion transport
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0016887	molecular_function	ATP hydrolysis activity
B	0032559	molecular_function	adenyl ribonucleotide binding
B	0042645	cellular_component	mitochondrial nucleoid
B	0043531	molecular_function	ADP binding
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0046034	biological_process	ATP metabolic process
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005758	cellular_component	mitochondrial intermembrane space
C	0005829	cellular_component	cytosol
C	0006754	biological_process	ATP biosynthetic process
C	0006811	biological_process	monoatomic ion transport
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0016887	molecular_function	ATP hydrolysis activity
C	0032559	molecular_function	adenyl ribonucleotide binding
C	0042645	cellular_component	mitochondrial nucleoid
C	0043531	molecular_function	ADP binding
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0046034	biological_process	ATP metabolic process
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0000166	molecular_function	nucleotide binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005758	cellular_component	mitochondrial intermembrane space
D	0005829	cellular_component	cytosol
D	0006754	biological_process	ATP biosynthetic process
D	0006811	biological_process	monoatomic ion transport
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0016887	molecular_function	ATP hydrolysis activity
D	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0000166	molecular_function	nucleotide binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005829	cellular_component	cytosol
E	0006754	biological_process	ATP biosynthetic process
E	0006811	biological_process	monoatomic ion transport
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0016887	molecular_function	ATP hydrolysis activity
E	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0000166	molecular_function	nucleotide binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005758	cellular_component	mitochondrial intermembrane space
F	0005829	cellular_component	cytosol
F	0006754	biological_process	ATP biosynthetic process
F	0006811	biological_process	monoatomic ion transport
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0016887	molecular_function	ATP hydrolysis activity
F	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0045259	cellular_component	proton-transporting ATP synthase complex
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0045259	cellular_component	proton-transporting ATP synthase complex
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0006754	biological_process	ATP biosynthetic process
I	0006811	biological_process	monoatomic ion transport
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0016887	molecular_function	ATP hydrolysis activity
I	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0006754	biological_process	ATP biosynthetic process
O	0006811	biological_process	monoatomic ion transport
O	0015986	biological_process	proton motive force-driven ATP synthesis
O	0016020	cellular_component	membrane
O	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
O	0045259	cellular_component	proton-transporting ATP synthase complex
O	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
O	1902600	biological_process	proton transmembrane transport
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0006754	biological_process	ATP biosynthetic process
T	0006811	biological_process	monoatomic ion transport
T	0015078	molecular_function	proton transmembrane transporter activity
T	0015986	biological_process	proton motive force-driven ATP synthesis
T	0045259	cellular_component	proton-transporting ATP synthase complex
T	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
T	1902600	biological_process	proton transmembrane transport
U	0015078	molecular_function	proton transmembrane transporter activity
U	0015986	biological_process	proton motive force-driven ATP synthesis
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0006754	biological_process	ATP biosynthetic process
V	0006811	biological_process	monoatomic ion transport
V	0015078	molecular_function	proton transmembrane transporter activity
V	0015986	biological_process	proton motive force-driven ATP synthesis
V	0045259	cellular_component	proton-transporting ATP synthase complex
V	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
V	1902600	biological_process	proton transmembrane transport
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0006754	biological_process	ATP biosynthetic process
W	0006811	biological_process	monoatomic ion transport
W	0015986	biological_process	proton motive force-driven ATP synthesis
W	0016887	molecular_function	ATP hydrolysis activity
W	0045259	cellular_component	proton-transporting ATP synthase complex
W	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
W	1902600	biological_process	proton transmembrane transport
X	0015986	biological_process	proton motive force-driven ATP synthesis
Y	0005739	cellular_component	mitochondrion
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0006754	biological_process	ATP biosynthetic process
Y	0006811	biological_process	monoatomic ion transport
Y	0015078	molecular_function	proton transmembrane transporter activity
Y	0015986	biological_process	proton motive force-driven ATP synthesis
Y	0031966	cellular_component	mitochondrial membrane
Y	0033615	biological_process	mitochondrial proton-transporting ATP synthase complex assembly
Y	0045259	cellular_component	proton-transporting ATP synthase complex
Y	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
Y	0065003	biological_process	protein-containing complex assembly
Y	1902600	biological_process	proton transmembrane transport
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0006754	biological_process	ATP biosynthetic process
Z	0006811	biological_process	monoatomic ion transport
Z	0015078	molecular_function	proton transmembrane transporter activity
Z	0015986	biological_process	proton motive force-driven ATP synthesis
Z	0031966	cellular_component	mitochondrial membrane
Z	0045259	cellular_component	proton-transporting ATP synthase complex
Z	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
Z	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAINVGLSVS

Chain	Residue	Details
A	PRO365-SER374
D	PRO346-SER355

---

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITnElvDiitGAsS

Chain	Residue	Details
G	ILE263-SER276

---

site_id	PS00389
Number of Residues	20
Details	ATPASE_DELTA ATP synthase delta (OSCP) subunit signature. LkLenvVKpEIkGGLIVElG

Chain	Residue	Details
O	LEU153-GLY172

---

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. SLGLRLGSNI

Chain	Residue	Details
T	SER172-ILE181

---

site_id	PS00605
Number of Residues	22
Details	ATPASE_C ATP synthase c subunit signature. SRNPsikdtVfPmaILgfaLsE

Chain	Residue	Details
0	SER38-GLU59

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	555
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Site: {"description":"Reversibly protonated during proton transport","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Modified residue: {"description":"N-formylmethionine","evidences":[{"source":"PubMed","id":"2894987","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	42
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Site: {"description":"Required for activity","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	10
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17761666","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17761666","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---