7THI
Human Bisphosphoglycerate Mutase complexed with 2-phosphoglycolate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004082 | molecular_function | bisphosphoglycerate mutase activity |
| A | 0004619 | molecular_function | phosphoglycerate mutase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006096 | biological_process | glycolytic process |
| A | 0006753 | biological_process | nucleoside phosphate metabolic process |
| A | 0007585 | biological_process | respiratory gaseous exchange by respiratory system |
| A | 0015671 | biological_process | oxygen transport |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016868 | molecular_function | intramolecular phosphotransferase activity |
| A | 0033554 | biological_process | cellular response to stress |
| A | 0042832 | biological_process | defense response to protozoan |
| A | 0048821 | biological_process | erythrocyte development |
| A | 0060856 | biological_process | establishment of blood-brain barrier |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0150076 | biological_process | neuroinflammatory response |
| A | 1901136 | biological_process | carbohydrate derivative catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004082 | molecular_function | bisphosphoglycerate mutase activity |
| B | 0004619 | molecular_function | phosphoglycerate mutase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006096 | biological_process | glycolytic process |
| B | 0006753 | biological_process | nucleoside phosphate metabolic process |
| B | 0007585 | biological_process | respiratory gaseous exchange by respiratory system |
| B | 0015671 | biological_process | oxygen transport |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016868 | molecular_function | intramolecular phosphotransferase activity |
| B | 0033554 | biological_process | cellular response to stress |
| B | 0042832 | biological_process | defense response to protozoan |
| B | 0048821 | biological_process | erythrocyte development |
| B | 0060856 | biological_process | establishment of blood-brain barrier |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0150076 | biological_process | neuroinflammatory response |
| B | 1901136 | biological_process | carbohydrate derivative catabolic process |
Functional Information from PROSITE/UniProt
| site_id | PS00175 |
| Number of Residues | 10 |
| Details | PG_MUTASE Phosphoglycerate mutase family phosphohistidine signature. MlRHGEgAwN |
| Chain | Residue | Details |
| A | MET8-ASN17 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Tele-phosphohistidine intermediate","evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 14 |
| Details | Site: {"description":"Not glycated","evidences":[{"source":"PubMed","id":"9832630","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"17052986","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 10 |
| Details | Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; in vitro","evidences":[{"source":"PubMed","id":"9832630","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (Glc) (glycation) lysine","evidences":[{"source":"PubMed","id":"9832630","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
