7TDZ

Cryo-EM model of protomer of the cytoplasmic ring of the nuclear pore complex from Xenopus laevis

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
b	0005643	cellular_component	nuclear pore
b	0005829	cellular_component	cytosol
b	0031080	cellular_component	nuclear pore outer ring
B	0005643	cellular_component	nuclear pore
B	0005829	cellular_component	cytosol
B	0031080	cellular_component	nuclear pore outer ring
c	0005643	cellular_component	nuclear pore
c	0005829	cellular_component	cytosol
c	0006406	biological_process	mRNA export from nucleus
c	0006606	biological_process	protein import into nucleus
c	0017056	molecular_function	structural constituent of nuclear pore
c	0031080	cellular_component	nuclear pore outer ring
c	0031965	cellular_component	nuclear membrane
c	0045893	biological_process	positive regulation of DNA-templated transcription
c	0072006	biological_process	nephron development
C	0005643	cellular_component	nuclear pore
C	0005829	cellular_component	cytosol
C	0006406	biological_process	mRNA export from nucleus
C	0006606	biological_process	protein import into nucleus
C	0017056	molecular_function	structural constituent of nuclear pore
C	0031080	cellular_component	nuclear pore outer ring
C	0031965	cellular_component	nuclear membrane
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0072006	biological_process	nephron development
d	0005634	cellular_component	nucleus
d	0005829	cellular_component	cytosol
d	0031080	cellular_component	nuclear pore outer ring
D	0005634	cellular_component	nucleus
D	0005829	cellular_component	cytosol
D	0031080	cellular_component	nuclear pore outer ring
e	0005198	molecular_function	structural molecule activity
E	0005198	molecular_function	structural molecule activity
g	0005198	molecular_function	structural molecule activity
g	0005643	cellular_component	nuclear pore
g	0005765	cellular_component	lysosomal membrane
g	0005829	cellular_component	cytosol
g	0006606	biological_process	protein import into nucleus
g	0030127	cellular_component	COPII vesicle coat
g	0031080	cellular_component	nuclear pore outer ring
g	0032008	biological_process	positive regulation of TOR signaling
g	0032527	biological_process	protein exit from endoplasmic reticulum
g	0090114	biological_process	COPII-coated vesicle budding
G	0005198	molecular_function	structural molecule activity
G	0005643	cellular_component	nuclear pore
G	0005765	cellular_component	lysosomal membrane
G	0005829	cellular_component	cytosol
G	0006606	biological_process	protein import into nucleus
G	0030127	cellular_component	COPII vesicle coat
G	0031080	cellular_component	nuclear pore outer ring
G	0032008	biological_process	positive regulation of TOR signaling
G	0032527	biological_process	protein exit from endoplasmic reticulum
G	0090114	biological_process	COPII-coated vesicle budding
h	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
h	0005643	cellular_component	nuclear pore
h	0005829	cellular_component	cytosol
h	0006406	biological_process	mRNA export from nucleus
h	0006606	biological_process	protein import into nucleus
h	0017056	molecular_function	structural constituent of nuclear pore
h	0031080	cellular_component	nuclear pore outer ring
h	0031965	cellular_component	nuclear membrane
H	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
H	0005643	cellular_component	nuclear pore
H	0005829	cellular_component	cytosol
H	0006406	biological_process	mRNA export from nucleus
H	0006606	biological_process	protein import into nucleus
H	0017056	molecular_function	structural constituent of nuclear pore
H	0031080	cellular_component	nuclear pore outer ring
H	0031965	cellular_component	nuclear membrane
i	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
i	0005643	cellular_component	nuclear pore
i	0005829	cellular_component	cytosol
i	0006606	biological_process	protein import into nucleus
i	0016973	biological_process	poly(A)+ mRNA export from nucleus
i	0017056	molecular_function	structural constituent of nuclear pore
i	0031080	cellular_component	nuclear pore outer ring
i	0048513	biological_process	animal organ development
i	0048731	biological_process	system development
I	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
I	0005643	cellular_component	nuclear pore
I	0005829	cellular_component	cytosol
I	0006606	biological_process	protein import into nucleus
I	0016973	biological_process	poly(A)+ mRNA export from nucleus
I	0017056	molecular_function	structural constituent of nuclear pore
I	0031080	cellular_component	nuclear pore outer ring
I	0048513	biological_process	animal organ development
I	0048731	biological_process	system development
l	0005634	cellular_component	nucleus
l	0005643	cellular_component	nuclear pore
l	0006913	biological_process	nucleocytoplasmic transport
l	0006999	biological_process	nuclear pore organization
l	0017056	molecular_function	structural constituent of nuclear pore
l	0044611	cellular_component	nuclear pore inner ring
L	0005634	cellular_component	nucleus
L	0005643	cellular_component	nuclear pore
L	0006913	biological_process	nucleocytoplasmic transport
L	0006999	biological_process	nuclear pore organization
L	0017056	molecular_function	structural constituent of nuclear pore
L	0044611	cellular_component	nuclear pore inner ring
M	0005096	molecular_function	GTPase activator activity
M	0005643	cellular_component	nuclear pore
M	0005737	cellular_component	cytoplasm
M	0031965	cellular_component	nuclear membrane
M	0046907	biological_process	intracellular transport
N	0005096	molecular_function	GTPase activator activity
N	0005643	cellular_component	nuclear pore
N	0005737	cellular_component	cytoplasm
N	0031965	cellular_component	nuclear membrane
N	0046907	biological_process	intracellular transport
O	0005096	molecular_function	GTPase activator activity
O	0005643	cellular_component	nuclear pore
O	0005737	cellular_component	cytoplasm
O	0031965	cellular_component	nuclear membrane
O	0046907	biological_process	intracellular transport
P	0005096	molecular_function	GTPase activator activity
P	0005643	cellular_component	nuclear pore
P	0005737	cellular_component	cytoplasm
P	0031965	cellular_component	nuclear membrane
P	0046907	biological_process	intracellular transport
Q	0005096	molecular_function	GTPase activator activity
Q	0005643	cellular_component	nuclear pore
Q	0005737	cellular_component	cytoplasm
Q	0031965	cellular_component	nuclear membrane
Q	0046907	biological_process	intracellular transport
r	0000055	biological_process	ribosomal large subunit export from nucleus
r	0000056	biological_process	ribosomal small subunit export from nucleus
r	0005643	cellular_component	nuclear pore
r	0006406	biological_process	mRNA export from nucleus
r	0006606	biological_process	protein import into nucleus
r	0006913	biological_process	nucleocytoplasmic transport
r	0017056	molecular_function	structural constituent of nuclear pore
R	0000055	biological_process	ribosomal large subunit export from nucleus
R	0000056	biological_process	ribosomal small subunit export from nucleus
R	0005643	cellular_component	nuclear pore
R	0006406	biological_process	mRNA export from nucleus
R	0006606	biological_process	protein import into nucleus
R	0006913	biological_process	nucleocytoplasmic transport
R	0017056	molecular_function	structural constituent of nuclear pore
s	0005643	cellular_component	nuclear pore
s	0006405	biological_process	RNA export from nucleus
s	0006406	biological_process	mRNA export from nucleus
s	0006606	biological_process	protein import into nucleus
s	0006886	biological_process	intracellular protein transport
s	0008139	molecular_function	nuclear localization sequence binding
s	0017056	molecular_function	structural constituent of nuclear pore
S	0005643	cellular_component	nuclear pore
S	0006405	biological_process	RNA export from nucleus
S	0006406	biological_process	mRNA export from nucleus
S	0006606	biological_process	protein import into nucleus
S	0006886	biological_process	intracellular protein transport
S	0008139	molecular_function	nuclear localization sequence binding
S	0017056	molecular_function	structural constituent of nuclear pore
t	0000922	cellular_component	spindle pole
t	0005515	molecular_function	protein binding
t	0005543	molecular_function	phospholipid binding
t	0005643	cellular_component	nuclear pore
t	0005813	cellular_component	centrosome
t	0005829	cellular_component	cytosol
t	0006405	biological_process	RNA export from nucleus
t	0006606	biological_process	protein import into nucleus
t	0017056	molecular_function	structural constituent of nuclear pore
t	0031965	cellular_component	nuclear membrane
t	0044613	cellular_component	nuclear pore central transport channel
T	0000922	cellular_component	spindle pole
T	0005515	molecular_function	protein binding
T	0005543	molecular_function	phospholipid binding
T	0005643	cellular_component	nuclear pore
T	0005813	cellular_component	centrosome
T	0005829	cellular_component	cytosol
T	0006405	biological_process	RNA export from nucleus
T	0006606	biological_process	protein import into nucleus
T	0017056	molecular_function	structural constituent of nuclear pore
T	0031965	cellular_component	nuclear membrane
T	0044613	cellular_component	nuclear pore central transport channel
U	0000972	biological_process	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
U	0005635	cellular_component	nuclear envelope
U	0005643	cellular_component	nuclear pore
U	0006405	biological_process	RNA export from nucleus
U	0006606	biological_process	protein import into nucleus
U	0006913	biological_process	nucleocytoplasmic transport
U	0017056	molecular_function	structural constituent of nuclear pore
U	0031965	cellular_component	nuclear membrane
U	0036228	biological_process	protein localization to nuclear inner membrane
U	0044611	cellular_component	nuclear pore inner ring

Functional Information from PROSITE/UniProt

site_id	PS00616
Number of Residues	15
Details	HIS_ACID_PHOSPHAT_1 Histidine acid phosphatases phosphohistidine signature. LlyAfhIyRHNyRkA

Chain	Residue	Details
A	LEU1078-ALA1092

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site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGgqDgMLCIWDV

Chain	Residue	Details
D	VAL230-VAL244
B	ILE140-LEU154

---

site_id	PS01358
Number of Residues	20
Details	ZF_RANBP2_1 Zinc finger RanBP2-type signature. WqCdc..ClatNaptstsCvcC

Chain	Residue	Details
P	TRP1349-CYS1368
P	TRP1413-CYS1432
P	TRP1474-CYS1493
P	TRP1534-CYS1553
P	TRP1594-CYS1613
P	TRP1661-CYS1680

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	78
Details	Repeat: {"description":"WD 1"}

Chain

Residue

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site_id	SWS_FT_FI3
Number of Residues	82
Details	Repeat: {"description":"WD 2"}

Chain

Residue

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site_id	SWS_FT_FI4
Number of Residues	82
Details	Repeat: {"description":"WD 3"}

Chain

Residue

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site_id	SWS_FT_FI5
Number of Residues	100
Details	Repeat: {"description":"WD 4"}

Chain

Residue

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site_id	SWS_FT_FI6
Number of Residues	82
Details	Repeat: {"description":"WD 5"}

Chain

Residue

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site_id	SWS_FT_FI7
Number of Residues	78
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

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