7TDO

Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004222	molecular_function	metalloendopeptidase activity
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030163	biological_process	protein catabolic process
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004222	molecular_function	metalloendopeptidase activity
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity
B	0008270	molecular_function	zinc ion binding
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0030163	biological_process	protein catabolic process
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004222	molecular_function	metalloendopeptidase activity
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008237	molecular_function	metallopeptidase activity
C	0008270	molecular_function	zinc ion binding
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0030163	biological_process	protein catabolic process
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0004176	molecular_function	ATP-dependent peptidase activity
D	0004222	molecular_function	metalloendopeptidase activity
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008237	molecular_function	metallopeptidase activity
D	0008270	molecular_function	zinc ion binding
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0030163	biological_process	protein catabolic process
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004222	molecular_function	metalloendopeptidase activity
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
E	0008237	molecular_function	metallopeptidase activity
E	0008270	molecular_function	zinc ion binding
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0030163	biological_process	protein catabolic process
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004222	molecular_function	metalloendopeptidase activity
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
F	0008237	molecular_function	metallopeptidase activity
F	0008270	molecular_function	zinc ion binding
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0030163	biological_process	protein catabolic process
F	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. IiVMaATNrpdiLDpALl.R

Chain	Residue	Details
A	ILE300-ARG318

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01458","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16484367","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	66
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16484367","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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