7TBV
Crystal structure of the shikimate kinase + 3-dehydroquinate dehydratase + 3-dehydroshikimate dehydrogenase domains of Aro1 from Candida albicans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| A | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| B | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| B | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| C | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| C | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| C | 0005737 | cellular_component | cytoplasm |
| D | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| D | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| D | 0005737 | cellular_component | cytoplasm |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGTGGTSRAAiYalhqmgcakiylvnr...TAAK |
| Chain | Residue | Details |
| A | VAL1394-LYS1424 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity => ECO:0000255|HAMAP-Rule:MF_03143 |
| Chain | Residue | Details |
| A | ARG1194 | |
| B | ARG1194 | |
| C | ARG1194 | |
| D | ARG1194 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03143 |
| Chain | Residue | Details |
| A | GLY865 | |
| B | GLY865 | |
| C | GLY865 | |
| D | GLY865 |
