7TBV
Crystal structure of the shikimate kinase + 3-dehydroquinate dehydratase + 3-dehydroshikimate dehydrogenase domains of Aro1 from Candida albicans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| A | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| B | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| B | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| C | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| C | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| C | 0005737 | cellular_component | cytoplasm |
| D | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| D | 0004764 | molecular_function | shikimate 3-dehydrogenase (NADP+) activity |
| D | 0005737 | cellular_component | cytoplasm |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGTGGTSRAAiYalhqmgcakiylvnr...TAAK |
| Chain | Residue | Details |
| A | VAL1394-LYS1424 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 836 |
| Details | Region: {"description":"3-dehydroquinase"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1120 |
| Details | Region: {"description":"Shikimate dehydrogenase"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
