7TBJ
Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A1 | 0005643 | cellular_component | nuclear pore |
| A1 | 0006913 | biological_process | nucleocytoplasmic transport |
| A1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| A2 | 0005643 | cellular_component | nuclear pore |
| A2 | 0006913 | biological_process | nucleocytoplasmic transport |
| A2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| A3 | 0005643 | cellular_component | nuclear pore |
| A3 | 0006913 | biological_process | nucleocytoplasmic transport |
| A3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| A4 | 0005643 | cellular_component | nuclear pore |
| A4 | 0006913 | biological_process | nucleocytoplasmic transport |
| A4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| A5 | 0005643 | cellular_component | nuclear pore |
| A5 | 0006913 | biological_process | nucleocytoplasmic transport |
| A5 | 0017056 | molecular_function | structural constituent of nuclear pore |
| A6 | 0005643 | cellular_component | nuclear pore |
| A6 | 0006913 | biological_process | nucleocytoplasmic transport |
| A6 | 0017056 | molecular_function | structural constituent of nuclear pore |
| D1 | 0005643 | cellular_component | nuclear pore |
| D1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| D2 | 0005643 | cellular_component | nuclear pore |
| D2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| D3 | 0005643 | cellular_component | nuclear pore |
| D3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| D4 | 0005643 | cellular_component | nuclear pore |
| D4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| D5 | 0005643 | cellular_component | nuclear pore |
| D5 | 0017056 | molecular_function | structural constituent of nuclear pore |
| D6 | 0005643 | cellular_component | nuclear pore |
| D6 | 0017056 | molecular_function | structural constituent of nuclear pore |
| D7 | 0005643 | cellular_component | nuclear pore |
| D7 | 0017056 | molecular_function | structural constituent of nuclear pore |
| F1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| F2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| G1 | 0005643 | cellular_component | nuclear pore |
| G1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| G2 | 0005643 | cellular_component | nuclear pore |
| G2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| I1 | 0005643 | cellular_component | nuclear pore |
| I2 | 0005643 | cellular_component | nuclear pore |
| I3 | 0005643 | cellular_component | nuclear pore |
| I4 | 0005643 | cellular_component | nuclear pore |
| I5 | 0005643 | cellular_component | nuclear pore |
| J1 | 0005643 | cellular_component | nuclear pore |
| J1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| J2 | 0005643 | cellular_component | nuclear pore |
| J2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| J3 | 0005643 | cellular_component | nuclear pore |
| J3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| J4 | 0005643 | cellular_component | nuclear pore |
| J4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| J5 | 0005643 | cellular_component | nuclear pore |
| J5 | 0017056 | molecular_function | structural constituent of nuclear pore |
| M1 | 0005643 | cellular_component | nuclear pore |
| M1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| M2 | 0005643 | cellular_component | nuclear pore |
| M2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| M3 | 0005643 | cellular_component | nuclear pore |
| M3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| M4 | 0005643 | cellular_component | nuclear pore |
| M4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| N1 | 0005643 | cellular_component | nuclear pore |
| N1 | 0006913 | biological_process | nucleocytoplasmic transport |
| N1 | 0008139 | molecular_function | nuclear localization sequence binding |
| N1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| N2 | 0005643 | cellular_component | nuclear pore |
| N2 | 0006913 | biological_process | nucleocytoplasmic transport |
| N2 | 0008139 | molecular_function | nuclear localization sequence binding |
| N2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| N3 | 0005643 | cellular_component | nuclear pore |
| N3 | 0006913 | biological_process | nucleocytoplasmic transport |
| N3 | 0008139 | molecular_function | nuclear localization sequence binding |
| N3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| N4 | 0005643 | cellular_component | nuclear pore |
| N4 | 0006913 | biological_process | nucleocytoplasmic transport |
| N4 | 0008139 | molecular_function | nuclear localization sequence binding |
| N4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| O1 | 0005643 | cellular_component | nuclear pore |
| O2 | 0005643 | cellular_component | nuclear pore |
| O3 | 0005643 | cellular_component | nuclear pore |
| O4 | 0005643 | cellular_component | nuclear pore |
| Q1 | 0003676 | molecular_function | nucleic acid binding |
| Q2 | 0003676 | molecular_function | nucleic acid binding |
| Q3 | 0003676 | molecular_function | nucleic acid binding |
| Q4 | 0003676 | molecular_function | nucleic acid binding |
| S1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| S2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| S3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| S4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| T1 | 0005643 | cellular_component | nuclear pore |
| T1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| T2 | 0005643 | cellular_component | nuclear pore |
| T2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| T3 | 0005643 | cellular_component | nuclear pore |
| T3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| T4 | 0005643 | cellular_component | nuclear pore |
| T4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| U1 | 0005643 | cellular_component | nuclear pore |
| U1 | 0017056 | molecular_function | structural constituent of nuclear pore |
| U2 | 0005643 | cellular_component | nuclear pore |
| U2 | 0017056 | molecular_function | structural constituent of nuclear pore |
| U3 | 0005643 | cellular_component | nuclear pore |
| U3 | 0017056 | molecular_function | structural constituent of nuclear pore |
| U4 | 0005643 | cellular_component | nuclear pore |
| U4 | 0017056 | molecular_function | structural constituent of nuclear pore |
| W1 | 0005198 | molecular_function | structural molecule activity |
| W2 | 0005198 | molecular_function | structural molecule activity |
| W3 | 0005198 | molecular_function | structural molecule activity |
| W4 | 0005198 | molecular_function | structural molecule activity |
| Y1 | 0005198 | molecular_function | structural molecule activity |
| Y2 | 0005198 | molecular_function | structural molecule activity |
| Y3 | 0005198 | molecular_function | structural molecule activity |
| Y4 | 0005198 | molecular_function | structural molecule activity |
| b1 | 0031080 | cellular_component | nuclear pore outer ring |
| b2 | 0031080 | cellular_component | nuclear pore outer ring |
| b3 | 0031080 | cellular_component | nuclear pore outer ring |
| b4 | 0031080 | cellular_component | nuclear pore outer ring |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGgqDgMLSIWDV |
| Chain | Residue | Details |
| a1 | VAL233-VAL247 |






