7TAA

FAMILY 13 ALPHA AMYLASE IN COMPLEX WITH ACARBOSE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004556	molecular_function	alpha-amylase activity
A	0005509	molecular_function	calcium ion binding
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0009277	cellular_component	fungal-type cell wall
A	0016052	biological_process	carbohydrate catabolic process
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030287	cellular_component	cell wall-bounded periplasmic space
A	0030428	cellular_component	cell septum
A	0031521	cellular_component	spitzenkorper
A	0032163	cellular_component	hyphal septin band
A	0043169	molecular_function	cation binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	BINDING SITE FOR RESIDUE ABC A 479

Chain	Residue
A	GLN35
A	HIS210
A	GLU230
A	LEU232
A	ASP233
A	GLY234
A	TYR256
A	HIS296
A	ASP297
A	ASP340
A	ARG344
A	TYR82
A	HOH513
A	HOH537
A	HOH563
A	HOH653
A	HOH693
A	HOH722
A	HOH751
A	TRP83
A	HIS122
A	TYR155
A	ARG204
A	ASP206
A	THR207
A	LYS209

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 480

Chain	Residue
A	ASN121
A	GLU162
A	ASP175
A	HIS210
A	HOH492
A	HOH505
A	HOH507

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000305|PubMed:9283074

Chain	Residue	Details
A	ASP206

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:9283074

Chain	Residue	Details
A	GLU230

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000305|PubMed:9283074

Chain	Residue	Details
A	TRP83
A	HIS122
A	ARG204
A	LYS209
A	GLY234
A	ARG344
A	GLN35
A	ASP297

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16880540, ECO:0000269|PubMed:6609921, ECO:0000269|PubMed:9283074

Chain	Residue	Details
A	ASN121
A	GLU162
A	ASP175
A	HIS210

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:9283074

Chain	Residue	Details
A	ASP206
A	GLU230

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	SITE: Transition state stabilizer => ECO:0000305|PubMed:9283074

Chain	Residue	Details
A	ASP297

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16880540

Chain	Residue	Details
A	ASN197

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ASP206
A	GLU230

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	HIS122
A	ASP206
A	ASP297
A	GLU230

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ASP206
A	ASP297
A	GLU230

---

site_id	CSA4
Number of Residues	5
Details	Annotated By Reference To The Literature 1amy

Chain	Residue	Details
A	ARG204
A	ASP206
A	HIS296
A	ASP297
A	GLU230

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