7T7R

Structure of Munc13-1 C1-C2B-MUN-C2C trimer between lipid bilayers

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005543	molecular_function	phospholipid binding
A	0007268	biological_process	chemical synaptic transmission
A	0019992	molecular_function	diacylglycerol binding
B	0005509	molecular_function	calcium ion binding
B	0005543	molecular_function	phospholipid binding
B	0007268	biological_process	chemical synaptic transmission
B	0019992	molecular_function	diacylglycerol binding
C	0005509	molecular_function	calcium ion binding
C	0005543	molecular_function	phospholipid binding
C	0007268	biological_process	chemical synaptic transmission
C	0019992	molecular_function	diacylglycerol binding

Functional Information from PROSITE/UniProt

site_id	PS00479
Number of Residues	50
Details	ZF_DAG_PE_1 Zinc finger phorbol-ester/DAG-type signature. HnFevwtattpty.CyeCeglLwgiarqgmr.CteCgvkcHekCqdllnad..C

Chain	Residue	Details
A	HIS39-CYS88

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	150
Details	ZN_FING: Phorbol-ester/DAG-type => ECO:0000255|PROSITE-ProRule:PRU00226

Chain	Residue	Details
A	PRO38-CYS88
B	PRO38-CYS88
C	PRO38-CYS88

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q62768

Chain	Residue	Details
A	CYS52
B	CYS72
B	CYS80
B	CYS88
C	CYS52
C	CYS55
C	CYS69
C	CYS72
C	CYS80
C	CYS88
A	CYS55
A	CYS69
A	CYS72
A	CYS80
A	CYS88
B	CYS52
B	CYS55
B	CYS69

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00041

Chain	Residue	Details
A	ASP177
B	ASP248
C	ASP177
C	ASP183
C	ASP229
C	ASP231
C	ASP248
A	ASP183
A	ASP229
A	ASP231
A	ASP248
B	ASP177
B	ASP183
B	ASP229
B	ASP231

---