Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7T7L

Structure of human G9a SET-domain (EHMT2) in complex with covalent inhibitor (Compound 1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0002039molecular_functionp53 binding
A0005634cellular_componentnucleus
A0008270molecular_functionzinc ion binding
A0016279molecular_functionprotein-lysine N-methyltransferase activity
A0042054molecular_functionhistone methyltransferase activity
B0002039molecular_functionp53 binding
B0005634cellular_componentnucleus
B0008270molecular_functionzinc ion binding
B0016279molecular_functionprotein-lysine N-methyltransferase activity
B0042054molecular_functionhistone methyltransferase activity
C0002039molecular_functionp53 binding
C0005634cellular_componentnucleus
C0008270molecular_functionzinc ion binding
C0016279molecular_functionprotein-lysine N-methyltransferase activity
C0042054molecular_functionhistone methyltransferase activity
D0002039molecular_functionp53 binding
D0005634cellular_componentnucleus
D0008270molecular_functionzinc ion binding
D0016279molecular_functionprotein-lysine N-methyltransferase activity
D0042054molecular_functionhistone methyltransferase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues68
DetailsBINDING:
ChainResidueDetails
ACYS974
AMET1048
ATYR1085
AASN1112
ACYS1115
ACYS1168
AGLN1169
ACYS1170
ACYS1175
BCYS974
BCYS976
ACYS976
BCYS980
BCYS985
BCYS987
BCYS1017
BCYS1021
BCYS1023
BCYS1027
BMET1048
BTYR1085
BASN1112
ACYS980
BCYS1115
BCYS1168
BGLN1169
BCYS1170
BCYS1175
CCYS974
CCYS976
CCYS980
CCYS985
CCYS987
ACYS985
CCYS1017
CCYS1021
CCYS1023
CCYS1027
CMET1048
CTYR1085
CASN1112
CCYS1115
CCYS1168
CGLN1169
ACYS987
CCYS1170
CCYS1175
DCYS974
DCYS976
DCYS980
DCYS985
DCYS987
DCYS1017
DCYS1021
DCYS1023
ACYS1017
DCYS1027
DMET1048
DTYR1085
DASN1112
DCYS1115
DCYS1168
DGLN1169
DCYS1170
DCYS1175
ACYS1021
ACYS1023
ACYS1027

site_idSWS_FT_FI2
Number of Residues4
DetailsSITE: Histone H3K9me binding => ECO:0000250
ChainResidueDetails
ATYR1067
BTYR1067
CTYR1067
DTYR1067

223532

PDB entries from 2024-08-07

PDB statisticsPDBj update infoContact PDBjnumon