7T4Q

CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0016032	biological_process	viral process
B	0019031	cellular_component	viral envelope
C	0019031	cellular_component	viral envelope
C	0019062	biological_process	virion attachment to host cell
C	0046718	biological_process	symbiont entry into host cell
C	0055036	cellular_component	virion membrane
C	0098670	biological_process	entry receptor-mediated virion attachment to host cell

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
H	TYR215-HIS221
G	TYR220-HIS226
I	TYR228-HIS234
J	TYR227-HIS233
F	TYR229-HIS235
K	TYR215-HIS221

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	63
Details	Region: {"description":"Interaction with gL","evidences":[{"source":"HAMAP-Rule","id":"MF_04033","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04033","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	213
Details	Domain: {"description":"gL betaherpesvirus-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01369","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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