7SXA

T-Plastin-F-actin complex, pre-bundling intermediate state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0005509	molecular_function	calcium ion binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005884	cellular_component	actin filament
A	0005886	cellular_component	plasma membrane
A	0031594	cellular_component	neuromuscular junction
A	0032432	cellular_component	actin filament bundle
A	0046872	molecular_function	metal ion binding
A	0051015	molecular_function	actin filament binding
A	0051017	biological_process	actin filament bundle assembly
A	0051639	biological_process	actin filament network formation
A	0060348	biological_process	bone development
A	0098693	biological_process	regulation of synaptic vesicle cycle
A	0098699	molecular_function	structural constituent of presynaptic actin cytoskeleton
A	0099140	biological_process	presynaptic actin cytoskeleton organization
B	0000166	molecular_function	nucleotide binding
B	0001725	cellular_component	stress fiber
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005856	cellular_component	cytoskeleton
B	0005865	cellular_component	striated muscle thin filament
B	0005884	cellular_component	actin filament
B	0015629	cellular_component	actin cytoskeleton
B	0016787	molecular_function	hydrolase activity
B	0030240	biological_process	skeletal muscle thin filament assembly
B	0048741	biological_process	skeletal muscle fiber development
C	0000166	molecular_function	nucleotide binding
C	0001725	cellular_component	stress fiber
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005856	cellular_component	cytoskeleton
C	0005865	cellular_component	striated muscle thin filament
C	0005884	cellular_component	actin filament
C	0015629	cellular_component	actin cytoskeleton
C	0016787	molecular_function	hydrolase activity
C	0030240	biological_process	skeletal muscle thin filament assembly
C	0048741	biological_process	skeletal muscle fiber development
D	0000166	molecular_function	nucleotide binding
D	0001725	cellular_component	stress fiber
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005856	cellular_component	cytoskeleton
D	0005865	cellular_component	striated muscle thin filament
D	0005884	cellular_component	actin filament
D	0015629	cellular_component	actin cytoskeleton
D	0016787	molecular_function	hydrolase activity
D	0030240	biological_process	skeletal muscle thin filament assembly
D	0048741	biological_process	skeletal muscle fiber development

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DLNSNGFICdyEL

Chain	Residue	Details
A	ASP25-LEU37
A	ASP65-PHE77

---

site_id	PS00019
Number of Residues	10
Details	ACTININ_1 Actinin-type actin-binding domain signature 1. EKyAFVNWIN

Chain	Residue	Details
A	GLU125-ASN134
A	GLU399-ASN408

---

site_id	PS00020
Number of Residues	25
Details	ACTININ_2 Actinin-type actin-binding domain signature 2. VvNIGAeDLrAgkphLvLGLLWqII

Chain	Residue	Details
A	VAL211-ILE235
A	LEU478-MET502

---

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
C	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WITKqEYDE

Chain	Residue	Details
C	TRP356-GLU364

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
C	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	MOD_RES: N-acetylcysteine; in intermediate form => ECO:0000250|UniProtKB:P62737

Chain	Residue	Details
C	CYS0
B	CYS0
D	CYS0
A	GLU36
A	ASP65
A	ASN67
A	ASP69
A	LYS71
A	GLU76

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N-acetylaspartate; in Actin, alpha skeletal muscle => ECO:0000269|PubMed:456601

Chain	Residue	Details
C	ASP1
B	ASP1
D	ASP1

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134

Chain	Residue	Details
C	MET44
C	MET47
B	MET44
B	MET47
D	MET44
D	MET47

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:12356759, ECO:0007744|PDB:1MDU

Chain	Residue	Details
C	HIC73
B	HIC73
D	HIC73

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133

Chain	Residue	Details
C	LYS84
B	LYS84
D	LYS84

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
A	THR391

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