7SVT

Mycobacterium tuberculosis 3-hydroxyl-ACP dehydratase HadAB in complex with 1,3-diarylpyrazolyl-acylsulfonamide inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0016836	molecular_function	hydro-lyase activity
A	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
H	0005515	molecular_function	protein binding
H	0005886	cellular_component	plasma membrane
H	0016836	molecular_function	hydro-lyase activity
H	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
O	0005515	molecular_function	protein binding
O	0005886	cellular_component	plasma membrane
O	0016836	molecular_function	hydro-lyase activity
O	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
V	0005515	molecular_function	protein binding
V	0005886	cellular_component	plasma membrane
V	0016836	molecular_function	hydro-lyase activity
V	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity

Functional Information from PROSITE/UniProt

site_id	PS00639
Number of Residues	11
Details	THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. IAHGMLTMGIG

Chain	Residue	Details
B	ILE56-GLY66

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