Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7SUN

Atomic model of prestin from gerbil (Meriones unguiculatus)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006091	biological_process	generation of precursor metabolites and energy
A	0006821	biological_process	chloride transport
A	0007605	biological_process	sensory perception of sound
A	0008218	biological_process	bioluminescence
A	0008271	molecular_function	secondary active sulfate transmembrane transporter activity
A	0008360	biological_process	regulation of cell shape
A	0015701	biological_process	bicarbonate transport
A	0016020	cellular_component	membrane
A	0016323	cellular_component	basolateral plasma membrane
A	0016328	cellular_component	lateral plasma membrane
A	0042803	molecular_function	protein homodimerization activity
A	0055085	biological_process	transmembrane transport
A	0140900	molecular_function	chloride:bicarbonate antiporter activity
A	1902358	biological_process	sulfate transmembrane transport
A	1902476	biological_process	chloride transmembrane transport
B	0006091	biological_process	generation of precursor metabolites and energy
B	0006821	biological_process	chloride transport
B	0007605	biological_process	sensory perception of sound
B	0008218	biological_process	bioluminescence
B	0008271	molecular_function	secondary active sulfate transmembrane transporter activity
B	0008360	biological_process	regulation of cell shape
B	0015701	biological_process	bicarbonate transport
B	0016020	cellular_component	membrane
B	0016323	cellular_component	basolateral plasma membrane
B	0016328	cellular_component	lateral plasma membrane
B	0042803	molecular_function	protein homodimerization activity
B	0055085	biological_process	transmembrane transport
B	0140900	molecular_function	chloride:bicarbonate antiporter activity
B	1902358	biological_process	sulfate transmembrane transport
B	1902476	biological_process	chloride transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS01130
Number of Residues	22
Details	SLC26A SLC26A transporters signature. PvFGLYSSfypvIMYcffGTSR

Chain	Residue	Details
A	PRO109-ARG130

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	50
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	132
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	30
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	108
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	18
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	34
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	42
Details	Transmembrane: {"description":"Helical; Name=5a","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	16
Details	Intramembrane: {"description":"Helical; Name=5b","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	34
Details	Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	18
Details	Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	36
Details	Transmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	36
Details	Transmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Name=13","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=14","evidences":[{"source":"PubMed","id":"35022426","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7SUN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P58743","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	2
Details	Site: {"description":"Controls the electromotile activity","evidences":[{"source":"UniProtKB","id":"A0FKN5","evidenceCode":"ECO:0000250"},{"source":"UniProtKB","id":"Q9EPH0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	2
Details	Site: {"description":"Contributes to anion binding","evidences":[{"source":"UniProtKB","id":"Q9EPH0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)