7STY

Crystal structure of human CORO1C

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001755	biological_process	neural crest cell migration
A	0001932	biological_process	regulation of protein phosphorylation
A	0001933	biological_process	negative regulation of protein phosphorylation
A	0003779	molecular_function	actin binding
A	0005515	molecular_function	protein binding
A	0005856	cellular_component	cytoskeleton
A	0005884	cellular_component	actin filament
A	0005886	cellular_component	plasma membrane
A	0005925	cellular_component	focal adhesion
A	0005938	cellular_component	cell cortex
A	0006909	biological_process	phagocytosis
A	0007015	biological_process	actin filament organization
A	0007165	biological_process	signal transduction
A	0010008	cellular_component	endosome membrane
A	0010632	biological_process	regulation of epithelial cell migration
A	0010633	biological_process	negative regulation of epithelial cell migration
A	0010762	biological_process	regulation of fibroblast migration
A	0015629	cellular_component	actin cytoskeleton
A	0016197	biological_process	endosomal transport
A	0016328	cellular_component	lateral plasma membrane
A	0016600	cellular_component	flotillin complex
A	0030017	cellular_component	sarcomere
A	0030027	cellular_component	lamellipodium
A	0031267	molecular_function	small GTPase binding
A	0031982	cellular_component	vesicle
A	0032587	cellular_component	ruffle membrane
A	0042383	cellular_component	sarcolemma
A	0044387	biological_process	negative regulation of protein kinase activity by regulation of protein phosphorylation
A	0045184	biological_process	establishment of protein localization
A	0045202	cellular_component	synapse
A	0045672	biological_process	positive regulation of osteoclast differentiation
A	0048246	biological_process	macrophage chemotaxis
A	0051015	molecular_function	actin filament binding
A	0051129	biological_process	negative regulation of cellular component organization
A	0051893	biological_process	regulation of focal adhesion assembly
A	0051895	biological_process	negative regulation of focal adhesion assembly
A	0090148	biological_process	membrane fission
A	0090630	biological_process	activation of GTPase activity
A	0097750	biological_process	endosome membrane tubulation
A	0140285	biological_process	endosome fission
A	1900024	biological_process	regulation of substrate adhesion-dependent cell spreading
A	1900025	biological_process	negative regulation of substrate adhesion-dependent cell spreading
A	1900027	biological_process	regulation of ruffle assembly
A	2000394	biological_process	positive regulation of lamellipodium morphogenesis

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSAgcDnAIIIWNV

Chain	Residue	Details
A	LEU146-VAL160

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Repeat: {"description":"WD 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	40
Details	Repeat: {"description":"WD 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12377779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	40
Details	Repeat: {"description":"WD 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12377779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	30
Details	Repeat: {"description":"WD 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12377779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	34
Details	Repeat: {"description":"WD 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12377779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	40
Details	Repeat: {"description":"WD 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00221","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12377779","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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