7SO7

Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016757	molecular_function	glycosyltransferase activity
B	0016757	molecular_function	glycosyltransferase activity

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
X	TYR196-HIS202
Y	TYR200-HIS206

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	178
Details	Region: {"description":"Four-helical bundle","evidences":[{"source":"PubMed","id":"25882477","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OQ7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6OQ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OQ7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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