7SMV

Crystallization of feline coronavirus Mpro with GC376 reveals mechanism of inhibition

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008233	molecular_function	peptidase activity
A	0019082	biological_process	viral protein processing
B	0008233	molecular_function	peptidase activity
B	0019082	biological_process	viral protein processing

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: For 3CL-PRO activity

Chain	Residue	Details
A	HIS41
A	CYS144
B	HIS41
B	CYS144

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Important for substrate recognition

Chain	Residue	Details
A	VAL150
B	VAL150

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site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Cleavage; by 3CL-PRO => ECO:0000250

Chain	Residue	Details
A	GLN302
B	GLN302

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