7SLV
Vanin-1 complexed with Compound 3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002526 | biological_process | acute inflammatory response |
| A | 0002544 | biological_process | chronic inflammatory response |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006954 | biological_process | inflammatory response |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0015938 | biological_process | coenzyme A catabolic process |
| A | 0015939 | biological_process | pantothenate metabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| A | 0017159 | molecular_function | pantetheine hydrolase activity |
| A | 0033089 | biological_process | positive regulation of T cell differentiation in thymus |
| A | 0035577 | cellular_component | azurophil granule membrane |
| A | 0045087 | biological_process | innate immune response |
| A | 0098552 | cellular_component | side of membrane |
| A | 0098609 | biological_process | cell-cell adhesion |
| A | 1902177 | biological_process | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 267 |
| Details | Domain: {"description":"CN hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25478849","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25478849","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU00054","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25478849","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15084671","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4CYF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CYG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CYY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4CYF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CYG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CYY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PDB","id":"4CYY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15084671","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4CYF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CYG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CYY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
