7SIP
Structure of shaker-IR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005249 | molecular_function | voltage-gated potassium channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0008076 | cellular_component | voltage-gated potassium channel complex |
| A | 0016020 | cellular_component | membrane |
| A | 0051260 | biological_process | protein homooligomerization |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005249 | molecular_function | voltage-gated potassium channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0008076 | cellular_component | voltage-gated potassium channel complex |
| B | 0016020 | cellular_component | membrane |
| B | 0051260 | biological_process | protein homooligomerization |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005249 | molecular_function | voltage-gated potassium channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0006813 | biological_process | potassium ion transport |
| C | 0008076 | cellular_component | voltage-gated potassium channel complex |
| C | 0016020 | cellular_component | membrane |
| C | 0051260 | biological_process | protein homooligomerization |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005249 | molecular_function | voltage-gated potassium channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0006813 | biological_process | potassium ion transport |
| D | 0008076 | cellular_component | voltage-gated potassium channel complex |
| D | 0016020 | cellular_component | membrane |
| D | 0051260 | biological_process | protein homooligomerization |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=Segment S1 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | ALA225-LEU246 | |
| B | ALA225-LEU246 | |
| C | ALA225-LEU246 | |
| D | ALA225-LEU246 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 296 |
| Details | TOPO_DOM: Extracellular => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | GLU247-PRO278 | |
| C | GLU333-SER357 | |
| C | PHE416-ILE429 | |
| C | PRO450-LYS456 | |
| D | GLU247-PRO278 | |
| D | GLU333-SER357 | |
| D | PHE416-ILE429 | |
| D | PRO450-LYS456 | |
| A | GLU333-SER357 | |
| A | PHE416-ILE429 | |
| A | PRO450-LYS456 | |
| B | GLU247-PRO278 | |
| B | GLU333-SER357 | |
| B | PHE416-ILE429 | |
| B | PRO450-LYS456 | |
| C | GLU247-PRO278 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=Segment S2 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | PHE279-ALA300 | |
| B | PHE279-ALA300 | |
| C | PHE279-ALA300 | |
| D | PHE279-ALA300 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 772 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | CYS301-VAL311 | |
| D | CYS301-VAL311 | |
| D | SER379-MET393 | |
| D | HIS486-ASP655 | |
| A | SER379-MET393 | |
| A | HIS486-ASP655 | |
| B | CYS301-VAL311 | |
| B | SER379-MET393 | |
| B | HIS486-ASP655 | |
| C | CYS301-VAL311 | |
| C | SER379-MET393 | |
| C | HIS486-ASP655 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 80 |
| Details | TRANSMEM: Helical; Name=Segment S3 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | MET312-ALA332 | |
| B | MET312-ALA332 | |
| C | MET312-ALA332 | |
| D | MET312-ALA332 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 80 |
| Details | TRANSMEM: Helical; Voltage-sensor; Name=Segment S4 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | LEU358-HIS378 | |
| B | LEU358-HIS378 | |
| C | LEU358-HIS378 | |
| D | LEU358-HIS378 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 84 |
| Details | TRANSMEM: Helical; Name=Segment S5 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | ARG394-TYR415 | |
| B | ARG394-TYR415 | |
| C | ARG394-TYR415 | |
| D | ARG394-TYR415 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 44 |
| Details | INTRAMEM: Helical; Name=Pore helix => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | PRO430-THR441 | |
| B | PRO430-THR441 | |
| C | PRO430-THR441 | |
| D | PRO430-THR441 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 28 |
| Details | INTRAMEM: INTRAMEM => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | THR442-THR449 | |
| B | THR442-THR449 | |
| C | THR442-THR449 | |
| D | THR442-THR449 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 112 |
| Details | TRANSMEM: Helical; Name=Segment S6 => ECO:0000250|UniProtKB:P63142 |
| Chain | Residue | Details |
| A | ILE457-TYR485 | |
| B | ILE457-TYR485 | |
| C | ILE457-TYR485 | |
| D | ILE457-TYR485 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17893096 |
| Chain | Residue | Details |
| A | ASN259 | |
| A | ASN263 | |
| B | ASN259 | |
| B | ASN263 | |
| C | ASN259 | |
| C | ASN263 | |
| D | ASN259 | |
| D | ASN263 |
