7SAB
Phencyclidine-bound GluN1a-GluN2B NMDA receptors
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005216 | molecular_function | monoatomic ion channel activity |
A | 0006811 | biological_process | monoatomic ion transport |
A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
A | 0016020 | cellular_component | membrane |
A | 0038023 | molecular_function | signaling receptor activity |
B | 0005216 | molecular_function | monoatomic ion channel activity |
B | 0006811 | biological_process | monoatomic ion transport |
B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
B | 0016020 | cellular_component | membrane |
B | 0038023 | molecular_function | signaling receptor activity |
C | 0005216 | molecular_function | monoatomic ion channel activity |
C | 0006811 | biological_process | monoatomic ion transport |
C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
C | 0016020 | cellular_component | membrane |
C | 0038023 | molecular_function | signaling receptor activity |
D | 0005216 | molecular_function | monoatomic ion channel activity |
D | 0006811 | biological_process | monoatomic ion transport |
D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
D | 0016020 | cellular_component | membrane |
D | 0038023 | molecular_function | signaling receptor activity |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1400 |
Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:24876489 |
Chain | Residue | Details |
B | ARG27-ASP557 | |
B | THR647-ASN817 | |
D | ARG27-ASP557 | |
D | THR647-ASN817 |
site_id | SWS_FT_FI2 |
Number of Residues | 104 |
Details | TRANSMEM: Helical => ECO:0000269|PubMed:24876489 |
Chain | Residue | Details |
B | VAL558-VAL576 | |
B | MET631-TYR646 | |
B | MET818-ILE837 | |
D | VAL558-VAL576 | |
D | MET631-TYR646 | |
D | MET818-ILE837 |
site_id | SWS_FT_FI3 |
Number of Residues | 64 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:24876489 |
Chain | Residue | Details |
B | PHE577-GLY603 | |
B | LYS624-ILE630 | |
D | PHE577-GLY603 | |
D | LYS624-ILE630 |
site_id | SWS_FT_FI4 |
Number of Residues | 38 |
Details | INTRAMEM: Discontinuously helical => ECO:0000305|PubMed:24876489 |
Chain | Residue | Details |
B | LYS604-PRO623 | |
D | LYS604-PRO623 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000305|PubMed:19910922, ECO:0007744|PDB:3JPY |
Chain | Residue | Details |
B | HIS127 | |
B | GLU284 | |
D | HIS127 | |
D | GLU284 |
site_id | SWS_FT_FI6 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:4PE5 |
Chain | Residue | Details |
B | THR514 | |
B | ARG519 | |
B | ASP732 | |
D | THR514 | |
D | ARG519 | |
D | ASP732 |
site_id | SWS_FT_FI7 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0007744|PDB:4PE5 |
Chain | Residue | Details |
B | SER690 | |
D | SER690 | |
C | GLN61 | |
C | ASP239 |
site_id | SWS_FT_FI8 |
Number of Residues | 2 |
Details | SITE: Functional determinant of NMDA receptors => ECO:0000250 |
Chain | Residue | Details |
B | ASN615 | |
D | ASN615 | |
C | ASN203 | |
C | ASN368 |
site_id | SWS_FT_FI9 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19910922, ECO:0000269|PubMed:24876489, ECO:0007744|PDB:3JPW, ECO:0007744|PDB:3JPY, ECO:0007744|PDB:3QEL, ECO:0007744|PDB:3QEM, ECO:0007744|PDB:4PE5 |
Chain | Residue | Details |
B | ASN74 | |
D | ASN74 |
site_id | SWS_FT_FI10 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19910922, ECO:0000269|PubMed:24876489, ECO:0007744|PDB:3JPW, ECO:0007744|PDB:3JPY, ECO:0007744|PDB:3QEL, ECO:0007744|PDB:3QEM, ECO:0007744|PDB:4PE5, ECO:0007744|PDB:5TPZ |
Chain | Residue | Details |
B | ASN341 | |
D | ASN341 |
site_id | SWS_FT_FI11 |
Number of Residues | 8 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
B | ASN348 | |
B | ASN444 | |
B | ASN491 | |
B | ASN542 | |
D | ASN348 | |
D | ASN444 | |
D | ASN491 | |
D | ASN542 |
site_id | SWS_FT_FI12 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:4PE5 |
Chain | Residue | Details |
B | ASN688 | |
D | ASN688 |
site_id | SWS_FT_FI13 |
Number of Residues | 6 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | GLN471 | |
A | GLN491 | |
A | ASN674 | |
C | GLN471 | |
C | GLN491 | |
C | ASN674 |