7S8U

Cryo-EM structure of a mammalian peptide transporter (PepT1/slc15a1) in nanodisc

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005427	molecular_function	proton-dependent oligopeptide secondary active transmembrane transporter activity
A	0005886	cellular_component	plasma membrane
A	0005903	cellular_component	brush border
A	0006857	biological_process	oligopeptide transport
A	0015031	biological_process	protein transport
A	0015293	molecular_function	symporter activity
A	0015333	molecular_function	peptide:proton symporter activity
A	0015833	biological_process	peptide transport
A	0016020	cellular_component	membrane
A	0016324	cellular_component	apical plasma membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0035673	molecular_function	oligopeptide transmembrane transporter activity
A	0042937	molecular_function	tripeptide transmembrane transporter activity
A	0042939	biological_process	tripeptide transport
A	0055085	biological_process	transmembrane transport
A	0071916	molecular_function	dipeptide transmembrane transporter activity
A	0140206	biological_process	dipeptide import across plasma membrane
A	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS01022
Number of Residues	25
Details	PTR2_1 PTR2 family proton/oligopeptide symporters signature 1. GALIADsWLGkfkTIvslSiVytiG

Chain	Residue	Details
A	GLY71-GLY95

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site_id	PS01023
Number of Residues	13
Details	PTR2_2 PTR2 family proton/oligopeptide symporters signature 2. FsiFYLaINAGSL

Chain	Residue	Details
A	PHE164-LEU176

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