Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7RW6

BORF2-APOBEC3Bctd Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
A	0006260	biological_process	DNA replication
A	0006974	biological_process	DNA damage response
A	0008643	biological_process	carbohydrate transport
A	0009263	biological_process	deoxyribonucleotide biosynthetic process
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0016032	biological_process	viral process
A	0016491	molecular_function	oxidoreductase activity
A	0019042	biological_process	viral latency
A	0019046	biological_process	release from viral latency
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	0071702	biological_process	organic substance transport
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
B	0003824	molecular_function	catalytic activity
B	0008270	molecular_function	zinc ion binding
B	0016787	molecular_function	hydrolase activity
C	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
C	0006260	biological_process	DNA replication
C	0006974	biological_process	DNA damage response
C	0008643	biological_process	carbohydrate transport
C	0009263	biological_process	deoxyribonucleotide biosynthetic process
C	0015144	molecular_function	carbohydrate transmembrane transporter activity
C	0015768	biological_process	maltose transport
C	0016020	cellular_component	membrane
C	0016032	biological_process	viral process
C	0016491	molecular_function	oxidoreductase activity
C	0019042	biological_process	viral latency
C	0019046	biological_process	release from viral latency
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0034219	biological_process	carbohydrate transmembrane transport
C	0034289	biological_process	detection of maltose stimulus
C	0042597	cellular_component	periplasmic space
C	0042956	biological_process	maltodextrin transmembrane transport
C	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	0055085	biological_process	transmembrane transport
C	0060326	biological_process	cell chemotaxis
C	0071702	biological_process	organic substance transport
C	1901982	molecular_function	maltose binding
C	1990060	cellular_component	maltose transport complex
D	0003824	molecular_function	catalytic activity
D	0008270	molecular_function	zinc ion binding
D	0016787	molecular_function	hydrolase activity

Functional Information from PROSITE/UniProt

site_id	PS00903
Number of Residues	41
Details	CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAElrFLdlvpslqldpaqiyrvtwfisws..........PCfswg....CageV

Chain	Residue	Details
B	HIS253-VAL293

site_id	PS00089
Number of Residues	23
Details	RIBORED_LARGE Ribonucleotide reductase large subunit signature. WsrLserivrdGLFNsqfIAlmP

Chain	Residue	Details
A	TRP572-PRO594

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO-263-ASN-246

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000255

Chain	Residue	Details
B	GLU255
D	GLU255
C	ASN387
C	GLU391

site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
B	HIS253
B	CYS284
B	CYS289
D	HIS253
D	CYS284
D	CYS289

site_id	SWS_FT_FI3
Number of Residues	10
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_04026

Chain	Residue	Details
A	THR171
A	GLY217
A	ASN387
A	PRO594
C	THR171
C	SER186
C	GLY217
C	ASN387
C	PRO594
A	SER186

site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Important for hydrogen atom transfer => ECO:0000255\|HAMAP-Rule:MF_04026

Chain	Residue	Details
C	CYS187
C	CYS403
A	CYS187
A	CYS403

site_id	SWS_FT_FI5
Number of Residues	4
Details	SITE: Important for electron transfer => ECO:0000255\|HAMAP-Rule:MF_04026

Chain	Residue	Details
A	TYR725
A	TYR726
C	TYR725
C	TYR726

site_id	SWS_FT_FI6
Number of Residues	4
Details	SITE: Interacts with thioredoxin/glutaredoxin => ECO:0000255\|HAMAP-Rule:MF_04026

Chain	Residue	Details
A	CYS822
A	CYS825
C	CYS822
C	CYS825

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)