7RUJ

E. coli cysteine desulfurase SufS N99A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001887	biological_process	selenium compound metabolic process
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006534	biological_process	cysteine metabolic process
A	0006790	biological_process	sulfur compound metabolic process
A	0008826	molecular_function	cysteine sulfinate desulfinase activity
A	0009000	molecular_function	selenocysteine lyase activity
A	0016226	biological_process	iron-sulfur cluster assembly
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0016829	molecular_function	lyase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031071	molecular_function	cysteine desulfurase activity
A	0042803	molecular_function	protein homodimerization activity

Functional Information from PROSITE/UniProt

site_id	PS00595
Number of Residues	20
Details	AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. CDFYvfSGHKlygpt.GiGiL

Chain	Residue	Details
A	CYS217-LEU236

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Cysteine persulfide intermediate"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 855

Chain	Residue	Details
A	HIS123	increase basicity, proton acceptor, proton donor
A	ASP200	electrostatic stabiliser, polar interaction
A	GLN203	electrostatic stabiliser, polar interaction
A	LYS226	covalently attached, electron pair acceptor, electron pair donor, nucleofuge, nucleophile, proton acceptor, proton donor
A	CYS364	covalently attached, nucleophile, proton donor

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