7RTM
Cryo-EM Structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE (SLC4A8)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005452 | molecular_function | solute:inorganic anion antiporter activity |
| A | 0006820 | biological_process | monoatomic anion transport |
| A | 0016020 | cellular_component | membrane |
| B | 0005452 | molecular_function | solute:inorganic anion antiporter activity |
| B | 0006820 | biological_process | monoatomic anion transport |
| B | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 440 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU479-LEU499 | |
| A | PRO905-PHE925 | |
| A | LEU963-LEU983 | |
| B | LEU479-LEU499 | |
| B | ILE508-ALA528 | |
| B | ILE566-VAL586 | |
| B | ALA596-LEU616 | |
| B | GLY688-VAL708 | |
| B | PHE732-SER752 | |
| B | PRO779-MET799 | |
| B | LEU825-ALA845 | |
| A | ILE508-ALA528 | |
| B | GLY882-ILE902 | |
| B | PRO905-PHE925 | |
| B | LEU963-LEU983 | |
| A | ILE566-VAL586 | |
| A | ALA596-LEU616 | |
| A | GLY688-VAL708 | |
| A | PHE732-SER752 | |
| A | PRO779-MET799 | |
| A | LEU825-ALA845 | |
| A | GLY882-ILE902 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 124 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU500-ARG507 | |
| B | PRO903-MET904 | |
| A | CYS587-GLU595 | |
| A | SER709-ASP731 | |
| A | ASP800-ASP824 | |
| A | PRO903-MET904 | |
| B | LEU500-ARG507 | |
| B | CYS587-GLU595 | |
| B | SER709-ASP731 | |
| B | ASP800-ASP824 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 404 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY529-CYS565 | |
| B | ASP926-CYS962 | |
| A | ALA617-HIS687 | |
| A | PRO753-ASN778 | |
| A | ALA846-THR881 | |
| A | ASP926-CYS962 | |
| B | GLY529-CYS565 | |
| B | ALA617-HIS687 | |
| B | PRO753-ASN778 | |
| B | ALA846-THR881 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc) asparagine => ECO:0000305|PubMed:34584093 |
| Chain | Residue | Details |
| A | ASN646 | |
| A | ASN666 | |
| B | ASN646 | |
| B | ASN666 |
