7RSL

Seipin forms a flexible cage at lipid droplet formation sites

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003674	molecular_function	molecular_function
A	0005515	molecular_function	protein binding
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005811	cellular_component	lipid droplet
A	0006629	biological_process	lipid metabolic process
A	0008104	biological_process	intracellular protein localization
A	0019216	biological_process	regulation of lipid metabolic process
A	0032541	cellular_component	cortical endoplasmic reticulum
A	0034389	biological_process	lipid droplet organization
A	0042802	molecular_function	identical protein binding
A	0046889	biological_process	positive regulation of lipid biosynthetic process
A	0055090	biological_process	acylglycerol homeostasis
A	0055091	biological_process	phospholipid homeostasis
A	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
A	0140042	biological_process	lipid droplet formation
A	1990044	biological_process	protein localization to lipid droplet
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005811	cellular_component	lipid droplet
B	0006629	biological_process	lipid metabolic process
B	0008104	biological_process	intracellular protein localization
B	0019216	biological_process	regulation of lipid metabolic process
B	0032541	cellular_component	cortical endoplasmic reticulum
B	0034389	biological_process	lipid droplet organization
B	0042802	molecular_function	identical protein binding
B	0046889	biological_process	positive regulation of lipid biosynthetic process
B	0055090	biological_process	acylglycerol homeostasis
B	0055091	biological_process	phospholipid homeostasis
B	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
B	0140042	biological_process	lipid droplet formation
B	1990044	biological_process	protein localization to lipid droplet
C	0003674	molecular_function	molecular_function
C	0005515	molecular_function	protein binding
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005811	cellular_component	lipid droplet
C	0006629	biological_process	lipid metabolic process
C	0008104	biological_process	intracellular protein localization
C	0019216	biological_process	regulation of lipid metabolic process
C	0032541	cellular_component	cortical endoplasmic reticulum
C	0034389	biological_process	lipid droplet organization
C	0042802	molecular_function	identical protein binding
C	0046889	biological_process	positive regulation of lipid biosynthetic process
C	0055090	biological_process	acylglycerol homeostasis
C	0055091	biological_process	phospholipid homeostasis
C	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
C	0140042	biological_process	lipid droplet formation
C	1990044	biological_process	protein localization to lipid droplet
D	0003674	molecular_function	molecular_function
D	0005515	molecular_function	protein binding
D	0005783	cellular_component	endoplasmic reticulum
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005811	cellular_component	lipid droplet
D	0006629	biological_process	lipid metabolic process
D	0008104	biological_process	intracellular protein localization
D	0019216	biological_process	regulation of lipid metabolic process
D	0032541	cellular_component	cortical endoplasmic reticulum
D	0034389	biological_process	lipid droplet organization
D	0042802	molecular_function	identical protein binding
D	0046889	biological_process	positive regulation of lipid biosynthetic process
D	0055090	biological_process	acylglycerol homeostasis
D	0055091	biological_process	phospholipid homeostasis
D	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
D	0140042	biological_process	lipid droplet formation
D	1990044	biological_process	protein localization to lipid droplet
E	0003674	molecular_function	molecular_function
E	0005515	molecular_function	protein binding
E	0005783	cellular_component	endoplasmic reticulum
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005811	cellular_component	lipid droplet
E	0006629	biological_process	lipid metabolic process
E	0008104	biological_process	intracellular protein localization
E	0019216	biological_process	regulation of lipid metabolic process
E	0032541	cellular_component	cortical endoplasmic reticulum
E	0034389	biological_process	lipid droplet organization
E	0042802	molecular_function	identical protein binding
E	0046889	biological_process	positive regulation of lipid biosynthetic process
E	0055090	biological_process	acylglycerol homeostasis
E	0055091	biological_process	phospholipid homeostasis
E	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
E	0140042	biological_process	lipid droplet formation
E	1990044	biological_process	protein localization to lipid droplet
F	0003674	molecular_function	molecular_function
F	0005515	molecular_function	protein binding
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005811	cellular_component	lipid droplet
F	0006629	biological_process	lipid metabolic process
F	0008104	biological_process	intracellular protein localization
F	0019216	biological_process	regulation of lipid metabolic process
F	0032541	cellular_component	cortical endoplasmic reticulum
F	0034389	biological_process	lipid droplet organization
F	0042802	molecular_function	identical protein binding
F	0046889	biological_process	positive regulation of lipid biosynthetic process
F	0055090	biological_process	acylglycerol homeostasis
F	0055091	biological_process	phospholipid homeostasis
F	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
F	0140042	biological_process	lipid droplet formation
F	1990044	biological_process	protein localization to lipid droplet
G	0003674	molecular_function	molecular_function
G	0005515	molecular_function	protein binding
G	0005783	cellular_component	endoplasmic reticulum
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0005811	cellular_component	lipid droplet
G	0006629	biological_process	lipid metabolic process
G	0008104	biological_process	intracellular protein localization
G	0019216	biological_process	regulation of lipid metabolic process
G	0032541	cellular_component	cortical endoplasmic reticulum
G	0034389	biological_process	lipid droplet organization
G	0042802	molecular_function	identical protein binding
G	0046889	biological_process	positive regulation of lipid biosynthetic process
G	0055090	biological_process	acylglycerol homeostasis
G	0055091	biological_process	phospholipid homeostasis
G	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
G	0140042	biological_process	lipid droplet formation
G	1990044	biological_process	protein localization to lipid droplet
H	0003674	molecular_function	molecular_function
H	0005515	molecular_function	protein binding
H	0005783	cellular_component	endoplasmic reticulum
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0005811	cellular_component	lipid droplet
H	0006629	biological_process	lipid metabolic process
H	0008104	biological_process	intracellular protein localization
H	0019216	biological_process	regulation of lipid metabolic process
H	0032541	cellular_component	cortical endoplasmic reticulum
H	0034389	biological_process	lipid droplet organization
H	0042802	molecular_function	identical protein binding
H	0046889	biological_process	positive regulation of lipid biosynthetic process
H	0055090	biological_process	acylglycerol homeostasis
H	0055091	biological_process	phospholipid homeostasis
H	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
H	0140042	biological_process	lipid droplet formation
H	1990044	biological_process	protein localization to lipid droplet
I	0003674	molecular_function	molecular_function
I	0005515	molecular_function	protein binding
I	0005783	cellular_component	endoplasmic reticulum
I	0005789	cellular_component	endoplasmic reticulum membrane
I	0005811	cellular_component	lipid droplet
I	0006629	biological_process	lipid metabolic process
I	0008104	biological_process	intracellular protein localization
I	0019216	biological_process	regulation of lipid metabolic process
I	0032541	cellular_component	cortical endoplasmic reticulum
I	0034389	biological_process	lipid droplet organization
I	0042802	molecular_function	identical protein binding
I	0046889	biological_process	positive regulation of lipid biosynthetic process
I	0055090	biological_process	acylglycerol homeostasis
I	0055091	biological_process	phospholipid homeostasis
I	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
I	0140042	biological_process	lipid droplet formation
I	1990044	biological_process	protein localization to lipid droplet
J	0003674	molecular_function	molecular_function
J	0005515	molecular_function	protein binding
J	0005783	cellular_component	endoplasmic reticulum
J	0005789	cellular_component	endoplasmic reticulum membrane
J	0005811	cellular_component	lipid droplet
J	0006629	biological_process	lipid metabolic process
J	0008104	biological_process	intracellular protein localization
J	0019216	biological_process	regulation of lipid metabolic process
J	0032541	cellular_component	cortical endoplasmic reticulum
J	0034389	biological_process	lipid droplet organization
J	0042802	molecular_function	identical protein binding
J	0046889	biological_process	positive regulation of lipid biosynthetic process
J	0055090	biological_process	acylglycerol homeostasis
J	0055091	biological_process	phospholipid homeostasis
J	0090155	biological_process	negative regulation of sphingolipid biosynthetic process
J	0140042	biological_process	lipid droplet formation
J	1990044	biological_process	protein localization to lipid droplet

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	200
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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