7RMV

Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000324	cellular_component	fungal-type vacuole
A	0003883	molecular_function	CTP synthase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0006541	biological_process	glutamine metabolic process
A	0008654	biological_process	phospholipid biosynthetic process
A	0016874	molecular_function	ligase activity
A	0019856	biological_process	pyrimidine nucleobase biosynthetic process
A	0042802	molecular_function	identical protein binding
A	0044210	biological_process	'de novo' CTP biosynthetic process
A	0097268	cellular_component	cytoophidium
B	0000324	cellular_component	fungal-type vacuole
B	0003883	molecular_function	CTP synthase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006241	biological_process	CTP biosynthetic process
B	0006541	biological_process	glutamine metabolic process
B	0008654	biological_process	phospholipid biosynthetic process
B	0016874	molecular_function	ligase activity
B	0019856	biological_process	pyrimidine nucleobase biosynthetic process
B	0042802	molecular_function	identical protein binding
B	0044210	biological_process	'de novo' CTP biosynthetic process
B	0097268	cellular_component	cytoophidium
C	0000324	cellular_component	fungal-type vacuole
C	0003883	molecular_function	CTP synthase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006221	biological_process	pyrimidine nucleotide biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0006541	biological_process	glutamine metabolic process
C	0008654	biological_process	phospholipid biosynthetic process
C	0016874	molecular_function	ligase activity
C	0019856	biological_process	pyrimidine nucleobase biosynthetic process
C	0042802	molecular_function	identical protein binding
C	0044210	biological_process	'de novo' CTP biosynthetic process
C	0097268	cellular_component	cytoophidium
D	0000324	cellular_component	fungal-type vacuole
D	0003883	molecular_function	CTP synthase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006221	biological_process	pyrimidine nucleotide biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0006541	biological_process	glutamine metabolic process
D	0008654	biological_process	phospholipid biosynthetic process
D	0016874	molecular_function	ligase activity
D	0019856	biological_process	pyrimidine nucleobase biosynthetic process
D	0042802	molecular_function	identical protein binding
D	0044210	biological_process	'de novo' CTP biosynthetic process
D	0097268	cellular_component	cytoophidium
E	0000324	cellular_component	fungal-type vacuole
E	0003883	molecular_function	CTP synthase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006221	biological_process	pyrimidine nucleotide biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0006541	biological_process	glutamine metabolic process
E	0008654	biological_process	phospholipid biosynthetic process
E	0016874	molecular_function	ligase activity
E	0019856	biological_process	pyrimidine nucleobase biosynthetic process
E	0042802	molecular_function	identical protein binding
E	0044210	biological_process	'de novo' CTP biosynthetic process
E	0097268	cellular_component	cytoophidium
F	0000324	cellular_component	fungal-type vacuole
F	0003883	molecular_function	CTP synthase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006221	biological_process	pyrimidine nucleotide biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0006541	biological_process	glutamine metabolic process
F	0008654	biological_process	phospholipid biosynthetic process
F	0016874	molecular_function	ligase activity
F	0019856	biological_process	pyrimidine nucleobase biosynthetic process
F	0042802	molecular_function	identical protein binding
F	0044210	biological_process	'de novo' CTP biosynthetic process
F	0097268	cellular_component	cytoophidium
G	0000324	cellular_component	fungal-type vacuole
G	0003883	molecular_function	CTP synthase activity
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006221	biological_process	pyrimidine nucleotide biosynthetic process
G	0006241	biological_process	CTP biosynthetic process
G	0006541	biological_process	glutamine metabolic process
G	0008654	biological_process	phospholipid biosynthetic process
G	0016874	molecular_function	ligase activity
G	0019856	biological_process	pyrimidine nucleobase biosynthetic process
G	0042802	molecular_function	identical protein binding
G	0044210	biological_process	'de novo' CTP biosynthetic process
G	0097268	cellular_component	cytoophidium
H	0000324	cellular_component	fungal-type vacuole
H	0003883	molecular_function	CTP synthase activity
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006221	biological_process	pyrimidine nucleotide biosynthetic process
H	0006241	biological_process	CTP biosynthetic process
H	0006541	biological_process	glutamine metabolic process
H	0008654	biological_process	phospholipid biosynthetic process
H	0016874	molecular_function	ligase activity
H	0019856	biological_process	pyrimidine nucleobase biosynthetic process
H	0042802	molecular_function	identical protein binding
H	0044210	biological_process	'de novo' CTP biosynthetic process
H	0097268	cellular_component	cytoophidium

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	ACT_SITE: For GATase activity => ECO:0000255|PROSITE-ProRule:PRU00605

Chain	Residue	Details
A	ILE412
D	ILE412
D	ALA554
D	SER556
E	ILE412
E	ALA554
E	SER556
F	ILE412
F	ALA554
F	SER556
G	ILE412
A	ALA554
G	ALA554
G	SER556
H	ILE412
H	ALA554
H	SER556
A	SER556
B	ILE412
B	ALA554
B	SER556
C	ILE412
C	ALA554
C	SER556

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site_id	SWS_FT_FI2
Number of Residues	16
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:12872131

Chain	Residue	Details
A	TYR430
F	TYR430
G	TYR430
H	TYR430
B	TYR430
C	TYR430
D	TYR430
E	TYR430

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