7RMC

Yeast CTP Synthase (Ura7) filament bound to CTP at low pH

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0000324	cellular_component	fungal-type vacuole
D	0003883	molecular_function	CTP synthase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006221	biological_process	pyrimidine nucleotide biosynthetic process
D	0006241	biological_process	CTP biosynthetic process
D	0006541	biological_process	glutamine metabolic process
D	0008654	biological_process	phospholipid biosynthetic process
D	0016874	molecular_function	ligase activity
D	0019856	biological_process	pyrimidine nucleobase biosynthetic process
D	0042802	molecular_function	identical protein binding
D	0044210	biological_process	'de novo' CTP biosynthetic process
D	0097268	cellular_component	cytoophidium
E	0000324	cellular_component	fungal-type vacuole
E	0003883	molecular_function	CTP synthase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006221	biological_process	pyrimidine nucleotide biosynthetic process
E	0006241	biological_process	CTP biosynthetic process
E	0006541	biological_process	glutamine metabolic process
E	0008654	biological_process	phospholipid biosynthetic process
E	0016874	molecular_function	ligase activity
E	0019856	biological_process	pyrimidine nucleobase biosynthetic process
E	0042802	molecular_function	identical protein binding
E	0044210	biological_process	'de novo' CTP biosynthetic process
E	0097268	cellular_component	cytoophidium
F	0000324	cellular_component	fungal-type vacuole
F	0003883	molecular_function	CTP synthase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006221	biological_process	pyrimidine nucleotide biosynthetic process
F	0006241	biological_process	CTP biosynthetic process
F	0006541	biological_process	glutamine metabolic process
F	0008654	biological_process	phospholipid biosynthetic process
F	0016874	molecular_function	ligase activity
F	0019856	biological_process	pyrimidine nucleobase biosynthetic process
F	0042802	molecular_function	identical protein binding
F	0044210	biological_process	'de novo' CTP biosynthetic process
F	0097268	cellular_component	cytoophidium
g	0000324	cellular_component	fungal-type vacuole
g	0003883	molecular_function	CTP synthase activity
g	0005524	molecular_function	ATP binding
g	0005737	cellular_component	cytoplasm
g	0006221	biological_process	pyrimidine nucleotide biosynthetic process
g	0006241	biological_process	CTP biosynthetic process
g	0006541	biological_process	glutamine metabolic process
g	0008654	biological_process	phospholipid biosynthetic process
g	0016874	molecular_function	ligase activity
g	0019856	biological_process	pyrimidine nucleobase biosynthetic process
g	0042802	molecular_function	identical protein binding
g	0044210	biological_process	'de novo' CTP biosynthetic process
g	0097268	cellular_component	cytoophidium
h	0000324	cellular_component	fungal-type vacuole
h	0003883	molecular_function	CTP synthase activity
h	0005524	molecular_function	ATP binding
h	0005737	cellular_component	cytoplasm
h	0006221	biological_process	pyrimidine nucleotide biosynthetic process
h	0006241	biological_process	CTP biosynthetic process
h	0006541	biological_process	glutamine metabolic process
h	0008654	biological_process	phospholipid biosynthetic process
h	0016874	molecular_function	ligase activity
h	0019856	biological_process	pyrimidine nucleobase biosynthetic process
h	0042802	molecular_function	identical protein binding
h	0044210	biological_process	'de novo' CTP biosynthetic process
h	0097268	cellular_component	cytoophidium
Q	0000324	cellular_component	fungal-type vacuole
Q	0003883	molecular_function	CTP synthase activity
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0006221	biological_process	pyrimidine nucleotide biosynthetic process
Q	0006241	biological_process	CTP biosynthetic process
Q	0006541	biological_process	glutamine metabolic process
Q	0008654	biological_process	phospholipid biosynthetic process
Q	0016874	molecular_function	ligase activity
Q	0019856	biological_process	pyrimidine nucleobase biosynthetic process
Q	0042802	molecular_function	identical protein binding
Q	0044210	biological_process	'de novo' CTP biosynthetic process
Q	0097268	cellular_component	cytoophidium
R	0000324	cellular_component	fungal-type vacuole
R	0003883	molecular_function	CTP synthase activity
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0006221	biological_process	pyrimidine nucleotide biosynthetic process
R	0006241	biological_process	CTP biosynthetic process
R	0006541	biological_process	glutamine metabolic process
R	0008654	biological_process	phospholipid biosynthetic process
R	0016874	molecular_function	ligase activity
R	0019856	biological_process	pyrimidine nucleobase biosynthetic process
R	0042802	molecular_function	identical protein binding
R	0044210	biological_process	'de novo' CTP biosynthetic process
R	0097268	cellular_component	cytoophidium
S	0000324	cellular_component	fungal-type vacuole
S	0003883	molecular_function	CTP synthase activity
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0006221	biological_process	pyrimidine nucleotide biosynthetic process
S	0006241	biological_process	CTP biosynthetic process
S	0006541	biological_process	glutamine metabolic process
S	0008654	biological_process	phospholipid biosynthetic process
S	0016874	molecular_function	ligase activity
S	0019856	biological_process	pyrimidine nucleobase biosynthetic process
S	0042802	molecular_function	identical protein binding
S	0044210	biological_process	'de novo' CTP biosynthetic process
S	0097268	cellular_component	cytoophidium
T	0000324	cellular_component	fungal-type vacuole
T	0003883	molecular_function	CTP synthase activity
T	0005524	molecular_function	ATP binding
T	0005737	cellular_component	cytoplasm
T	0006221	biological_process	pyrimidine nucleotide biosynthetic process
T	0006241	biological_process	CTP biosynthetic process
T	0006541	biological_process	glutamine metabolic process
T	0008654	biological_process	phospholipid biosynthetic process
T	0016874	molecular_function	ligase activity
T	0019856	biological_process	pyrimidine nucleobase biosynthetic process
T	0042802	molecular_function	identical protein binding
T	0044210	biological_process	'de novo' CTP biosynthetic process
T	0097268	cellular_component	cytoophidium
U	0000324	cellular_component	fungal-type vacuole
U	0003883	molecular_function	CTP synthase activity
U	0005524	molecular_function	ATP binding
U	0005737	cellular_component	cytoplasm
U	0006221	biological_process	pyrimidine nucleotide biosynthetic process
U	0006241	biological_process	CTP biosynthetic process
U	0006541	biological_process	glutamine metabolic process
U	0008654	biological_process	phospholipid biosynthetic process
U	0016874	molecular_function	ligase activity
U	0019856	biological_process	pyrimidine nucleobase biosynthetic process
U	0042802	molecular_function	identical protein binding
U	0044210	biological_process	'de novo' CTP biosynthetic process
U	0097268	cellular_component	cytoophidium
V	0000324	cellular_component	fungal-type vacuole
V	0003883	molecular_function	CTP synthase activity
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0006221	biological_process	pyrimidine nucleotide biosynthetic process
V	0006241	biological_process	CTP biosynthetic process
V	0006541	biological_process	glutamine metabolic process
V	0008654	biological_process	phospholipid biosynthetic process
V	0016874	molecular_function	ligase activity
V	0019856	biological_process	pyrimidine nucleobase biosynthetic process
V	0042802	molecular_function	identical protein binding
V	0044210	biological_process	'de novo' CTP biosynthetic process
V	0097268	cellular_component	cytoophidium
W	0000324	cellular_component	fungal-type vacuole
W	0003883	molecular_function	CTP synthase activity
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0006221	biological_process	pyrimidine nucleotide biosynthetic process
W	0006241	biological_process	CTP biosynthetic process
W	0006541	biological_process	glutamine metabolic process
W	0008654	biological_process	phospholipid biosynthetic process
W	0016874	molecular_function	ligase activity
W	0019856	biological_process	pyrimidine nucleobase biosynthetic process
W	0042802	molecular_function	identical protein binding
W	0044210	biological_process	'de novo' CTP biosynthetic process
W	0097268	cellular_component	cytoophidium

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	ACT_SITE: For GATase activity => ECO:0000255|PROSITE-ProRule:PRU00605

Chain	Residue	Details
V	CYS404
F	CYS404
F	SER546
F	PRO548
g	CYS404
g	SER546
g	PRO548
Q	CYS404
Q	SER546
Q	PRO548
S	CYS404
V	SER546
S	SER546
S	PRO548
U	CYS404
U	SER546
U	PRO548
h	CYS404
h	SER546
h	PRO548
R	CYS404
R	SER546
V	PRO548
R	PRO548
T	CYS404
T	SER546
T	PRO548
W	CYS404
W	SER546
W	PRO548
D	CYS404
D	SER546
D	PRO548
E	CYS404
E	SER546
E	PRO548

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site_id	SWS_FT_FI2
Number of Residues	24
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:12872131

Chain	Residue	Details
V	LYS422
Q	LYS422
S	LYS422
U	LYS422
h	LYS422
R	LYS422
T	LYS422
W	LYS422
D	LYS422
E	LYS422
F	LYS422
g	LYS422

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