7REI

The crystal structure of nickel bound human ADO C18S C239S variant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0046872	molecular_function	metal ion binding
A	0047800	molecular_function	cysteamine dioxygenase activity
A	0051213	molecular_function	dioxygenase activity
A	0071456	biological_process	cellular response to hypoxia

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:34508780, ECO:0007744|PDB:7REI

Chain	Residue	Details
A	HIS112
A	HIS114
A	HIS193

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: 3'-(S-cysteinyl)-tyrosine (Cys-Tyr) => ECO:0000269|PubMed:29752763

Chain	Residue	Details
A	CYS220
A	TYR223

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