7R94

T-Plastin-F-actin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001725	cellular_component	stress fiber
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005856	cellular_component	cytoskeleton
A	0005865	cellular_component	striated muscle thin filament
A	0005884	cellular_component	actin filament
A	0016787	molecular_function	hydrolase activity
A	0030240	biological_process	skeletal muscle thin filament assembly
A	0048741	biological_process	skeletal muscle fiber development
B	0001725	cellular_component	stress fiber
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005856	cellular_component	cytoskeleton
B	0005865	cellular_component	striated muscle thin filament
B	0005884	cellular_component	actin filament
B	0016787	molecular_function	hydrolase activity
B	0030240	biological_process	skeletal muscle thin filament assembly
B	0048741	biological_process	skeletal muscle fiber development
C	0001725	cellular_component	stress fiber
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005856	cellular_component	cytoskeleton
C	0005865	cellular_component	striated muscle thin filament
C	0005884	cellular_component	actin filament
C	0016787	molecular_function	hydrolase activity
C	0030240	biological_process	skeletal muscle thin filament assembly
C	0048741	biological_process	skeletal muscle fiber development
D	0001725	cellular_component	stress fiber
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005856	cellular_component	cytoskeleton
D	0005865	cellular_component	striated muscle thin filament
D	0005884	cellular_component	actin filament
D	0016787	molecular_function	hydrolase activity
D	0030240	biological_process	skeletal muscle thin filament assembly
D	0048741	biological_process	skeletal muscle fiber development
E	0001725	cellular_component	stress fiber
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005856	cellular_component	cytoskeleton
E	0005865	cellular_component	striated muscle thin filament
E	0005884	cellular_component	actin filament
E	0016787	molecular_function	hydrolase activity
E	0030240	biological_process	skeletal muscle thin filament assembly
E	0048741	biological_process	skeletal muscle fiber development
F	0003779	molecular_function	actin binding
F	0005509	molecular_function	calcium ion binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005884	cellular_component	actin filament
F	0005886	cellular_component	plasma membrane
F	0032432	cellular_component	actin filament bundle
F	0046872	molecular_function	metal ion binding
F	0051015	molecular_function	actin filament binding
F	0051017	biological_process	actin filament bundle assembly
F	0051639	biological_process	actin filament network formation
F	0060348	biological_process	bone development
G	0003779	molecular_function	actin binding
G	0005509	molecular_function	calcium ion binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005884	cellular_component	actin filament
G	0005886	cellular_component	plasma membrane
G	0032432	cellular_component	actin filament bundle
G	0046872	molecular_function	metal ion binding
G	0051015	molecular_function	actin filament binding
G	0051017	biological_process	actin filament bundle assembly
G	0051639	biological_process	actin filament network formation
G	0060348	biological_process	bone development
H	0003779	molecular_function	actin binding
H	0005509	molecular_function	calcium ion binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005884	cellular_component	actin filament
H	0005886	cellular_component	plasma membrane
H	0032432	cellular_component	actin filament bundle
H	0046872	molecular_function	metal ion binding
H	0051015	molecular_function	actin filament binding
H	0051017	biological_process	actin filament bundle assembly
H	0051639	biological_process	actin filament network formation
H	0060348	biological_process	bone development

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DLNSNGFICdyEL

Chain	Residue	Details
F	ASP25-LEU37
F	ASP65-PHE77

---

site_id	PS00019
Number of Residues	10
Details	ACTININ_1 Actinin-type actin-binding domain signature 1. EKyAFVNWIN

Chain	Residue	Details
F	GLU125-ASN134
F	GLU399-ASN408

---

site_id	PS00020
Number of Residues	25
Details	ACTININ_2 Actinin-type actin-binding domain signature 2. VvNIGAeDLrAgkphLvLGLLWqII

Chain	Residue	Details
F	VAL211-ILE235
F	LEU478-MET502

---

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
C	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WITKqEYDE

Chain	Residue	Details
C	TRP356-GLU364

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
C	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	27
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448

Chain	Residue	Details
F	ASP25
G	ASP25
G	ASN27
G	ASN29
G	GLU36
G	ASP65
G	ASN67
G	ASP69
G	LYS71
G	GLU76
H	ASP25
F	ASN27
H	ASN27
H	ASN29
H	GLU36
H	ASP65
H	ASN67
H	ASP69
H	LYS71
H	GLU76
F	ASN29
F	GLU36
F	ASP65
F	ASN67
F	ASP69
F	LYS71
F	GLU76

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q99K51

Chain	Residue	Details
F	SER268
G	SER268
H	SER268
D	ASP1
E	ASP1

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
F	SER293
E	MET47
G	SER293
H	SER293
B	MET47
A	MET44
A	MET47
D	MET44
D	MET47
E	MET44

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
F	SER326
G	SER326
H	SER326
D	HIC73
E	HIC73

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
F	SER339
G	SER339
H	SER339
D	LYS84
E	LYS84

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
F	THR391
G	THR391
H	THR391

---