7R77

Cryo-EM structure of DNMT5 binary complex with hemimethylated DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003677	molecular_function	DNA binding
A	0003682	molecular_function	chromatin binding
A	0003886	molecular_function	DNA (cytosine-5-)-methyltransferase activity
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005694	cellular_component	chromosome
A	0006281	biological_process	DNA repair
A	0006338	biological_process	chromatin remodeling
A	0006346	biological_process	DNA methylation-dependent constitutive heterochromatin formation
A	0008094	molecular_function	ATP-dependent activity, acting on DNA
A	0008168	molecular_function	methyltransferase activity
A	0010424	biological_process	obsolete DNA methylation on cytosine within a CG sequence
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0032259	biological_process	methylation
A	0043565	molecular_function	sequence-specific DNA binding
A	0120328	molecular_function	ATP-dependent DNA (cytosine-5-)-methyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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