7QXF

Fructose-6-phosphate aldolase (FSA) mutant R134V, S166G, with covalently bound active site ligand

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006000	biological_process	fructose metabolic process
A	0016829	molecular_function	lyase activity
A	0016832	molecular_function	aldehyde-lyase activity
A	0042182	biological_process	ketone catabolic process
A	0042802	molecular_function	identical protein binding
A	0097023	molecular_function	fructose 6-phosphate aldolase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006000	biological_process	fructose metabolic process
B	0016829	molecular_function	lyase activity
B	0016832	molecular_function	aldehyde-lyase activity
B	0042182	biological_process	ketone catabolic process
B	0042802	molecular_function	identical protein binding
B	0097023	molecular_function	fructose 6-phosphate aldolase activity
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0006000	biological_process	fructose metabolic process
C	0016829	molecular_function	lyase activity
C	0016832	molecular_function	aldehyde-lyase activity
C	0042182	biological_process	ketone catabolic process
C	0042802	molecular_function	identical protein binding
C	0097023	molecular_function	fructose 6-phosphate aldolase activity
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0006000	biological_process	fructose metabolic process
D	0016829	molecular_function	lyase activity
D	0016832	molecular_function	aldehyde-lyase activity
D	0042182	biological_process	ketone catabolic process
D	0042802	molecular_function	identical protein binding
D	0097023	molecular_function	fructose 6-phosphate aldolase activity
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0006000	biological_process	fructose metabolic process
E	0016829	molecular_function	lyase activity
E	0016832	molecular_function	aldehyde-lyase activity
E	0042182	biological_process	ketone catabolic process
E	0042802	molecular_function	identical protein binding
E	0097023	molecular_function	fructose 6-phosphate aldolase activity
F	0005737	cellular_component	cytoplasm
F	0005975	biological_process	carbohydrate metabolic process
F	0006000	biological_process	fructose metabolic process
F	0016829	molecular_function	lyase activity
F	0016832	molecular_function	aldehyde-lyase activity
F	0042182	biological_process	ketone catabolic process
F	0042802	molecular_function	identical protein binding
F	0097023	molecular_function	fructose 6-phosphate aldolase activity
G	0005737	cellular_component	cytoplasm
G	0005975	biological_process	carbohydrate metabolic process
G	0006000	biological_process	fructose metabolic process
G	0016829	molecular_function	lyase activity
G	0016832	molecular_function	aldehyde-lyase activity
G	0042182	biological_process	ketone catabolic process
G	0042802	molecular_function	identical protein binding
G	0097023	molecular_function	fructose 6-phosphate aldolase activity
H	0005737	cellular_component	cytoplasm
H	0005975	biological_process	carbohydrate metabolic process
H	0006000	biological_process	fructose metabolic process
H	0016829	molecular_function	lyase activity
H	0016832	molecular_function	aldehyde-lyase activity
H	0042182	biological_process	ketone catabolic process
H	0042802	molecular_function	identical protein binding
H	0097023	molecular_function	fructose 6-phosphate aldolase activity
I	0005737	cellular_component	cytoplasm
I	0005975	biological_process	carbohydrate metabolic process
I	0006000	biological_process	fructose metabolic process
I	0016829	molecular_function	lyase activity
I	0016832	molecular_function	aldehyde-lyase activity
I	0042182	biological_process	ketone catabolic process
I	0042802	molecular_function	identical protein binding
I	0097023	molecular_function	fructose 6-phosphate aldolase activity
J	0005737	cellular_component	cytoplasm
J	0005975	biological_process	carbohydrate metabolic process
J	0006000	biological_process	fructose metabolic process
J	0016829	molecular_function	lyase activity
J	0016832	molecular_function	aldehyde-lyase activity
J	0042182	biological_process	ketone catabolic process
J	0042802	molecular_function	identical protein binding
J	0097023	molecular_function	fructose 6-phosphate aldolase activity
K	0005737	cellular_component	cytoplasm
K	0005975	biological_process	carbohydrate metabolic process
K	0006000	biological_process	fructose metabolic process
K	0016829	molecular_function	lyase activity
K	0016832	molecular_function	aldehyde-lyase activity
K	0042182	biological_process	ketone catabolic process
K	0042802	molecular_function	identical protein binding
K	0097023	molecular_function	fructose 6-phosphate aldolase activity
L	0005737	cellular_component	cytoplasm
L	0005975	biological_process	carbohydrate metabolic process
L	0006000	biological_process	fructose metabolic process
L	0016829	molecular_function	lyase activity
L	0016832	molecular_function	aldehyde-lyase activity
L	0042182	biological_process	ketone catabolic process
L	0042802	molecular_function	identical protein binding
L	0097023	molecular_function	fructose 6-phosphate aldolase activity
M	0005737	cellular_component	cytoplasm
M	0005975	biological_process	carbohydrate metabolic process
M	0006000	biological_process	fructose metabolic process
M	0016829	molecular_function	lyase activity
M	0016832	molecular_function	aldehyde-lyase activity
M	0042182	biological_process	ketone catabolic process
M	0042802	molecular_function	identical protein binding
M	0097023	molecular_function	fructose 6-phosphate aldolase activity
N	0005737	cellular_component	cytoplasm
N	0005975	biological_process	carbohydrate metabolic process
N	0006000	biological_process	fructose metabolic process
N	0016829	molecular_function	lyase activity
N	0016832	molecular_function	aldehyde-lyase activity
N	0042182	biological_process	ketone catabolic process
N	0042802	molecular_function	identical protein binding
N	0097023	molecular_function	fructose 6-phosphate aldolase activity
O	0005737	cellular_component	cytoplasm
O	0005975	biological_process	carbohydrate metabolic process
O	0006000	biological_process	fructose metabolic process
O	0016829	molecular_function	lyase activity
O	0016832	molecular_function	aldehyde-lyase activity
O	0042182	biological_process	ketone catabolic process
O	0042802	molecular_function	identical protein binding
O	0097023	molecular_function	fructose 6-phosphate aldolase activity

Functional Information from PROSITE/UniProt

site_id	PS00958
Number of Residues	18
Details	TRANSALDOLASE_2 Transaldolase active site. IvVKVPvTaEGLaAiKmL

Chain	Residue	Details
A	ILE82-LEU99

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site_id	PS01054
Number of Residues	9
Details	TRANSALDOLASE_1 Transaldolase signature 1. GVTTNPSII

Chain	Residue	Details
A	GLY24-ILE32

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000269|PubMed:11120740, ECO:0000269|PubMed:12051943

Chain	Residue	Details
A	I2F85
B	I2F85
C	I2F85
D	I2F85
E	I2F85
F	I2F85
G	I2F85
H	I2F85
I	I2F85
J	I2F85
K	I2F85
L	I2F85
M	I2F85
N	I2F85
O	I2F85

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