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7QP6

Structure of the human 48S initiation complex in open state (h48S AUG open)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
10001732biological_processformation of cytoplasmic translation initiation complex
10002183biological_processcytoplasmic translational initiation
10003676molecular_functionnucleic acid binding
10003723molecular_functionRNA binding
10003743molecular_functiontranslation initiation factor activity
10005515molecular_functionprotein binding
10005737cellular_componentcytoplasm
10005829cellular_componentcytosol
10005852cellular_componenteukaryotic translation initiation factor 3 complex
10006412biological_processtranslation
10006413biological_processtranslational initiation
10006446biological_processregulation of translational initiation
10010494cellular_componentcytoplasmic stress granule
10016282cellular_componenteukaryotic 43S preinitiation complex
10031369molecular_functiontranslation initiation factor binding
10033290cellular_componenteukaryotic 48S preinitiation complex
10045202cellular_componentsynapse
10060090molecular_functionmolecular adaptor activity
10070062cellular_componentextracellular exosome
10071541cellular_componenteukaryotic translation initiation factor 3 complex, eIF3m
10075522biological_processIRES-dependent viral translational initiation
10075525biological_processviral translational termination-reinitiation
30001732biological_processformation of cytoplasmic translation initiation complex
30002183biological_processcytoplasmic translational initiation
30003723molecular_functionRNA binding
30003743molecular_functiontranslation initiation factor activity
30005515molecular_functionprotein binding
30005634cellular_componentnucleus
30005737cellular_componentcytoplasm
30005829cellular_componentcytosol
30005852cellular_componenteukaryotic translation initiation factor 3 complex
30006412biological_processtranslation
30006413biological_processtranslational initiation
30006446biological_processregulation of translational initiation
30016020cellular_componentmembrane
30016282cellular_componenteukaryotic 43S preinitiation complex
30032991cellular_componentprotein-containing complex
30033290cellular_componenteukaryotic 48S preinitiation complex
30043022molecular_functionribosome binding
40001732biological_processformation of cytoplasmic translation initiation complex
40002183biological_processcytoplasmic translational initiation
40003743molecular_functiontranslation initiation factor activity
40004843molecular_functioncysteine-type deubiquitinase activity
40005515molecular_functionprotein binding
40005737cellular_componentcytoplasm
40005829cellular_componentcytosol
40005852cellular_componenteukaryotic translation initiation factor 3 complex
40006412biological_processtranslation
40006413biological_processtranslational initiation
40006508biological_processproteolysis
40008233molecular_functionpeptidase activity
40008234molecular_functioncysteine-type peptidase activity
40008237molecular_functionmetallopeptidase activity
40016020cellular_componentmembrane
40016282cellular_componenteukaryotic 43S preinitiation complex
40031369molecular_functiontranslation initiation factor binding
40033290cellular_componenteukaryotic 48S preinitiation complex
40042802molecular_functionidentical protein binding
40045202cellular_componentsynapse
40071541cellular_componenteukaryotic translation initiation factor 3 complex, eIF3m
40075522biological_processIRES-dependent viral translational initiation
40140492molecular_functionmetal-dependent deubiquitinase activity
50001650cellular_componentfibrillar center
50001732biological_processformation of cytoplasmic translation initiation complex
50002183biological_processcytoplasmic translational initiation
50003723molecular_functionRNA binding
50003743molecular_functiontranslation initiation factor activity
50005515molecular_functionprotein binding
50005654cellular_componentnucleoplasm
50005730cellular_componentnucleolus
50005737cellular_componentcytoplasm
50005829cellular_componentcytosol
50005852cellular_componenteukaryotic translation initiation factor 3 complex
50006412biological_processtranslation
50006413biological_processtranslational initiation
50016020cellular_componentmembrane
50016282cellular_componenteukaryotic 43S preinitiation complex
50032991cellular_componentprotein-containing complex
50033290cellular_componenteukaryotic 48S preinitiation complex
50045202cellular_componentsynapse
50075525biological_processviral translational termination-reinitiation
60001732biological_processformation of cytoplasmic translation initiation complex
60002183biological_processcytoplasmic translational initiation
60003743molecular_functiontranslation initiation factor activity
60005515molecular_functionprotein binding
60005737cellular_componentcytoplasm
60005829cellular_componentcytosol
60005852cellular_componenteukaryotic translation initiation factor 3 complex
60006412biological_processtranslation
60006413biological_processtranslational initiation
60016282cellular_componenteukaryotic 43S preinitiation complex
60031369molecular_functiontranslation initiation factor binding
60032991cellular_componentprotein-containing complex
60033290cellular_componenteukaryotic 48S preinitiation complex
60071541cellular_componenteukaryotic translation initiation factor 3 complex, eIF3m
80001732biological_processformation of cytoplasmic translation initiation complex
80002183biological_processcytoplasmic translational initiation
80003723molecular_functionRNA binding
80003743molecular_functiontranslation initiation factor activity
80005515molecular_functionprotein binding
80005737cellular_componentcytoplasm
80005829cellular_componentcytosol
80005852cellular_componenteukaryotic translation initiation factor 3 complex
80006412biological_processtranslation
80006413biological_processtranslational initiation
80006446biological_processregulation of translational initiation
80008233molecular_functionpeptidase activity
80008237molecular_functionmetallopeptidase activity
80016020cellular_componentmembrane
80016282cellular_componenteukaryotic 43S preinitiation complex
80032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
80033290cellular_componenteukaryotic 48S preinitiation complex
80070062cellular_componentextracellular exosome
80071541cellular_componenteukaryotic translation initiation factor 3 complex, eIF3m
80140492molecular_functionmetal-dependent deubiquitinase activity
90002181biological_processcytoplasmic translation
90003723molecular_functionRNA binding
90003730molecular_functionmRNA 3'-UTR binding
90003735molecular_functionstructural constituent of ribosome
90005515molecular_functionprotein binding
90005737cellular_componentcytoplasm
90005783cellular_componentendoplasmic reticulum
90005829cellular_componentcytosol
90005840cellular_componentribosome
90006412biological_processtranslation
90022625cellular_componentcytosolic large ribosomal subunit
90048027molecular_functionmRNA 5'-UTR binding
91990904cellular_componentribonucleoprotein complex
B0002181biological_processcytoplasmic translation
B0003723molecular_functionRNA binding
B0003735molecular_functionstructural constituent of ribosome
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005730cellular_componentnucleolus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005840cellular_componentribosome
B0005925cellular_componentfocal adhesion
B0006412biological_processtranslation
B0016020cellular_componentmembrane
B0019843molecular_functionrRNA binding
B0022626cellular_componentcytosolic ribosome
B0022627cellular_componentcytosolic small ribosomal subunit
B0032040cellular_componentsmall-subunit processome
B0042274biological_processribosomal small subunit biogenesis
B0070062cellular_componentextracellular exosome
B1990904cellular_componentribonucleoprotein complex
C0002181biological_processcytoplasmic translation
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005730cellular_componentnucleolus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005840cellular_componentribosome
C0005925cellular_componentfocal adhesion
C0006412biological_processtranslation
C0008284biological_processpositive regulation of cell population proliferation
C0015935cellular_componentsmall ribosomal subunit
C0016020cellular_componentmembrane
C0019843molecular_functionrRNA binding
C0022626cellular_componentcytosolic ribosome
C0022627cellular_componentcytosolic small ribosomal subunit
C0032040cellular_componentsmall-subunit processome
C0036464cellular_componentcytoplasmic ribonucleoprotein granule
C0042274biological_processribosomal small subunit biogenesis
C0045202cellular_componentsynapse
C0045727biological_processpositive regulation of translation
C0070062cellular_componentextracellular exosome
C1990904cellular_componentribonucleoprotein complex
D0002181biological_processcytoplasmic translation
D0003723molecular_functionRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005730cellular_componentnucleolus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005840cellular_componentribosome
D0005925cellular_componentfocal adhesion
D0006412biological_processtranslation
D0006417biological_processregulation of translation
D0008284biological_processpositive regulation of cell population proliferation
D0015935cellular_componentsmall ribosomal subunit
D0016020cellular_componentmembrane
D0019843molecular_functionrRNA binding
D0022626cellular_componentcytosolic ribosome
D0022627cellular_componentcytosolic small ribosomal subunit
D0032040cellular_componentsmall-subunit processome
D0042274biological_processribosomal small subunit biogenesis
D0043226cellular_componentorganelle
D0045182molecular_functiontranslation regulator activity
D0045202cellular_componentsynapse
D0070062cellular_componentextracellular exosome
D1990904cellular_componentribonucleoprotein complex
E0002181biological_processcytoplasmic translation
E0003723molecular_functionRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005730cellular_componentnucleolus
E0005737cellular_componentcytoplasm
E0005783cellular_componentendoplasmic reticulum
E0005791cellular_componentrough endoplasmic reticulum
E0005829cellular_componentcytosol
E0005840cellular_componentribosome
E0006412biological_processtranslation
E0015935cellular_componentsmall ribosomal subunit
E0016020cellular_componentmembrane
E0022626cellular_componentcytosolic ribosome
E0022627cellular_componentcytosolic small ribosomal subunit
E0032040cellular_componentsmall-subunit processome
E0034063biological_processstress granule assembly
E0042274biological_processribosomal small subunit biogenesis
E0045202cellular_componentsynapse
E1990145biological_processmaintenance of translational fidelity
E1990904cellular_componentribonucleoprotein complex
F0003735molecular_functionstructural constituent of ribosome
F0005840cellular_componentribosome
F0006412biological_processtranslation
G0001843biological_processneural tube closure
G0002181biological_processcytoplasmic translation
G0003723molecular_functionRNA binding
G0003730molecular_functionmRNA 3'-UTR binding
G0003735molecular_functionstructural constituent of ribosome
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005730cellular_componentnucleolus
G0005737cellular_componentcytoplasm
G0005783cellular_componentendoplasmic reticulum
G0005813cellular_componentcentrosome
G0005829cellular_componentcytosol
G0005840cellular_componentribosome
G0005856cellular_componentcytoskeleton
G0005925cellular_componentfocal adhesion
G0006364biological_processrRNA processing
G0006412biological_processtranslation
G0010628biological_processpositive regulation of gene expression
G0014033biological_processneural crest cell differentiation
G0016020cellular_componentmembrane
G0019901molecular_functionprotein kinase binding
G0022626cellular_componentcytosolic ribosome
G0022627cellular_componentcytosolic small ribosomal subunit
G0032040cellular_componentsmall-subunit processome
G0032991cellular_componentprotein-containing complex
G0042274biological_processribosomal small subunit biogenesis
G0045202cellular_componentsynapse
G0048027molecular_functionmRNA 5'-UTR binding
G0050821biological_processprotein stabilization
G1902255biological_processpositive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
G1904667biological_processnegative regulation of ubiquitin protein ligase activity
G1990904cellular_componentribonucleoprotein complex
G1990948molecular_functionubiquitin ligase inhibitor activity
G2000059biological_processnegative regulation of ubiquitin-dependent protein catabolic process
H0000028biological_processribosomal small subunit assembly
H0002181biological_processcytoplasmic translation
H0003677molecular_functionDNA binding
H0003723molecular_functionRNA binding
H0003735molecular_functionstructural constituent of ribosome
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005730cellular_componentnucleolus
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0005840cellular_componentribosome
H0006364biological_processrRNA processing
H0006412biological_processtranslation
H0008270molecular_functionzinc ion binding
H0014069cellular_componentpostsynaptic density
H0022626cellular_componentcytosolic ribosome
H0022627cellular_componentcytosolic small ribosomal subunit
H0032040cellular_componentsmall-subunit processome
H0042274biological_processribosomal small subunit biogenesis
H0045202cellular_componentsynapse
H0046872molecular_functionmetal ion binding
H0098793cellular_componentpresynapse
H0098794cellular_componentpostsynapse
H0140236biological_processtranslation at presynapse
H0140242biological_processtranslation at postsynapse
H1990904cellular_componentribonucleoprotein complex
I0002181biological_processcytoplasmic translation
I0003723molecular_functionRNA binding
I0003729molecular_functionmRNA binding
I0003735molecular_functionstructural constituent of ribosome
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005730cellular_componentnucleolus
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0005840cellular_componentribosome
I0005925cellular_componentfocal adhesion
I0006412biological_processtranslation
I0014069cellular_componentpostsynaptic density
I0016020cellular_componentmembrane
I0022626cellular_componentcytosolic ribosome
I0022627cellular_componentcytosolic small ribosomal subunit
I0032040cellular_componentsmall-subunit processome
I0033119biological_processnegative regulation of RNA splicing
I0042274biological_processribosomal small subunit biogenesis
I0048027molecular_functionmRNA 5'-UTR binding
I0070062cellular_componentextracellular exosome
I0070181molecular_functionsmall ribosomal subunit rRNA binding
I1990904cellular_componentribonucleoprotein complex
J0002181biological_processcytoplasmic translation
J0003723molecular_functionRNA binding
J0003735molecular_functionstructural constituent of ribosome
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005730cellular_componentnucleolus
J0005737cellular_componentcytoplasm
J0005829cellular_componentcytosol
J0005840cellular_componentribosome
J0006412biological_processtranslation
J0008284biological_processpositive regulation of cell population proliferation
J0009615biological_processresponse to virus
J0016020cellular_componentmembrane
J0022626cellular_componentcytosolic ribosome
J0022627cellular_componentcytosolic small ribosomal subunit
J0032040cellular_componentsmall-subunit processome
J0042274biological_processribosomal small subunit biogenesis
J0045202cellular_componentsynapse
J0045787biological_processpositive regulation of cell cycle
J0070062cellular_componentextracellular exosome
J1990904cellular_componentribonucleoprotein complex
K0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K0000461biological_processendonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K0002181biological_processcytoplasmic translation
K0003723molecular_functionRNA binding
K0003735molecular_functionstructural constituent of ribosome
K0005515molecular_functionprotein binding
K0005654cellular_componentnucleoplasm
K0005737cellular_componentcytoplasm
K0005783cellular_componentendoplasmic reticulum
K0005791cellular_componentrough endoplasmic reticulum
K0005829cellular_componentcytosol
K0005840cellular_componentribosome
K0006412biological_processtranslation
K0015935cellular_componentsmall ribosomal subunit
K0022626cellular_componentcytosolic ribosome
K0022627cellular_componentcytosolic small ribosomal subunit
K0045202cellular_componentsynapse
K1990904cellular_componentribonucleoprotein complex
L0002181biological_processcytoplasmic translation
L0003723molecular_functionRNA binding
L0003729molecular_functionmRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005730cellular_componentnucleolus
L0005737cellular_componentcytoplasm
L0005829cellular_componentcytosol
L0005840cellular_componentribosome
L0005925cellular_componentfocal adhesion
L0006412biological_processtranslation
L0015935cellular_componentsmall ribosomal subunit
L0016020cellular_componentmembrane
L0017134molecular_functionfibroblast growth factor binding
L0019899molecular_functionenzyme binding
L0022626cellular_componentcytosolic ribosome
L0022627cellular_componentcytosolic small ribosomal subunit
L0045296molecular_functioncadherin binding
L0051443biological_processpositive regulation of ubiquitin-protein transferase activity
L0070062cellular_componentextracellular exosome
L1990904cellular_componentribonucleoprotein complex
M0002181biological_processcytoplasmic translation
M0003723molecular_functionRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0005634cellular_componentnucleus
M0005654cellular_componentnucleoplasm
M0005730cellular_componentnucleolus
M0005737cellular_componentcytoplasm
M0005829cellular_componentcytosol
M0005840cellular_componentribosome
M0005925cellular_componentfocal adhesion
M0006364biological_processrRNA processing
M0006412biological_processtranslation
M0006413biological_processtranslational initiation
M0016020cellular_componentmembrane
M0022626cellular_componentcytosolic ribosome
M0022627cellular_componentcytosolic small ribosomal subunit
M0032040cellular_componentsmall-subunit processome
M0034101biological_processerythrocyte homeostasis
M0042274biological_processribosomal small subunit biogenesis
M1990904cellular_componentribonucleoprotein complex
N0000028biological_processribosomal small subunit assembly
N0001618molecular_functionvirus receptor activity
N0002181biological_processcytoplasmic translation
N0003677molecular_functionDNA binding
N0003723molecular_functionRNA binding
N0003735molecular_functionstructural constituent of ribosome
N0005055molecular_functionlaminin receptor activity
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0005654cellular_componentnucleoplasm
N0005737cellular_componentcytoplasm
N0005829cellular_componentcytosol
N0005840cellular_componentribosome
N0005886cellular_componentplasma membrane
N0006412biological_processtranslation
N0007155biological_processcell adhesion
N0015935cellular_componentsmall ribosomal subunit
N0016020cellular_componentmembrane
N0022626cellular_componentcytosolic ribosome
N0022627cellular_componentcytosolic small ribosomal subunit
N0043022molecular_functionribosome binding
N0043236molecular_functionlaminin binding
N0046718biological_processsymbiont entry into host cell
N0070062cellular_componentextracellular exosome
N0140374biological_processantiviral innate immune response
N1990904cellular_componentribonucleoprotein complex
O0002181biological_processcytoplasmic translation
O0003723molecular_functionRNA binding
O0003735molecular_functionstructural constituent of ribosome
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005654cellular_componentnucleoplasm
O0005730cellular_componentnucleolus
O0005737cellular_componentcytoplasm
O0005783cellular_componentendoplasmic reticulum
O0005829cellular_componentcytosol
O0005840cellular_componentribosome
O0005925cellular_componentfocal adhesion
O0006412biological_processtranslation
O0006413biological_processtranslational initiation
O0022626cellular_componentcytosolic ribosome
O0022627cellular_componentcytosolic small ribosomal subunit
O0030154biological_processcell differentiation
O0032040cellular_componentsmall-subunit processome
O0042274biological_processribosomal small subunit biogenesis
O0043066biological_processnegative regulation of apoptotic process
O0048027molecular_functionmRNA 5'-UTR binding
O0070062cellular_componentextracellular exosome
O1990904cellular_componentribonucleoprotein complex
P0000028biological_processribosomal small subunit assembly
P0000122biological_processnegative regulation of transcription by RNA polymerase II
P0002181biological_processcytoplasmic translation
P0003723molecular_functionRNA binding
P0003735molecular_functionstructural constituent of ribosome
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005654cellular_componentnucleoplasm
P0005730cellular_componentnucleolus
P0005737cellular_componentcytoplasm
P0005829cellular_componentcytosol
P0005840cellular_componentribosome
P0005925cellular_componentfocal adhesion
P0006412biological_processtranslation
P0006417biological_processregulation of translation
P0014069cellular_componentpostsynaptic density
P0015935cellular_componentsmall ribosomal subunit
P0016020cellular_componentmembrane
P0022626cellular_componentcytosolic ribosome
P0022627cellular_componentcytosolic small ribosomal subunit
P0030218biological_processerythrocyte differentiation
P0030490biological_processmaturation of SSU-rRNA
P0032040cellular_componentsmall-subunit processome
P0042274biological_processribosomal small subunit biogenesis
P0045182molecular_functiontranslation regulator activity
P0045202cellular_componentsynapse
P0048027molecular_functionmRNA 5'-UTR binding
P0070062cellular_componentextracellular exosome
P1990904cellular_componentribonucleoprotein complex
Q0002181biological_processcytoplasmic translation
Q0003723molecular_functionRNA binding
Q0003729molecular_functionmRNA binding
Q0003735molecular_functionstructural constituent of ribosome
Q0005515molecular_functionprotein binding
Q0005654cellular_componentnucleoplasm
Q0005737cellular_componentcytoplasm
Q0005783cellular_componentendoplasmic reticulum
Q0005791cellular_componentrough endoplasmic reticulum
Q0005829cellular_componentcytosol
Q0005840cellular_componentribosome
Q0006412biological_processtranslation
Q0015935cellular_componentsmall ribosomal subunit
Q0016020cellular_componentmembrane
Q0022626cellular_componentcytosolic ribosome
Q0022627cellular_componentcytosolic small ribosomal subunit
Q0033119biological_processnegative regulation of RNA splicing
Q0045202cellular_componentsynapse
Q0045296molecular_functioncadherin binding
Q0070062cellular_componentextracellular exosome
Q0098556cellular_componentcytoplasmic side of rough endoplasmic reticulum membrane
Q1990904cellular_componentribonucleoprotein complex
R0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
R0002181biological_processcytoplasmic translation
R0003723molecular_functionRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005654cellular_componentnucleoplasm
R0005730cellular_componentnucleolus
R0005737cellular_componentcytoplasm
R0005783cellular_componentendoplasmic reticulum
R0005829cellular_componentcytosol
R0005840cellular_componentribosome
R0005925cellular_componentfocal adhesion
R0006412biological_processtranslation
R0016020cellular_componentmembrane
R0022626cellular_componentcytosolic ribosome
R0022627cellular_componentcytosolic small ribosomal subunit
R0032040cellular_componentsmall-subunit processome
R0042274biological_processribosomal small subunit biogenesis
R0070062cellular_componentextracellular exosome
R1990904cellular_componentribonucleoprotein complex
S0000082biological_processG1/S transition of mitotic cell cycle
S0000278biological_processmitotic cell cycle
S0001890biological_processplacenta development
S0002181biological_processcytoplasmic translation
S0002309biological_processT cell proliferation involved in immune response
S0003723molecular_functionRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0005515molecular_functionprotein binding
S0005634cellular_componentnucleus
S0005654cellular_componentnucleoplasm
S0005730cellular_componentnucleolus
S0005737cellular_componentcytoplasm
S0005783cellular_componentendoplasmic reticulum
S0005829cellular_componentcytosol
S0005840cellular_componentribosome
S0006364biological_processrRNA processing
S0006412biological_processtranslation
S0006924biological_processactivation-induced cell death of T cells
S0007369biological_processgastrulation
S0008284biological_processpositive regulation of cell population proliferation
S0015935cellular_componentsmall ribosomal subunit
S0016020cellular_componentmembrane
S0019901molecular_functionprotein kinase binding
S0022605biological_processmammalian oogenesis stage
S0022626cellular_componentcytosolic ribosome
S0022627cellular_componentcytosolic small ribosomal subunit
S0030425cellular_componentdendrite
S0031929biological_processTOR signaling
S0032040cellular_componentsmall-subunit processome
S0033077biological_processT cell differentiation in thymus
S0036464cellular_componentcytoplasmic ribonucleoprotein granule
S0042274biological_processribosomal small subunit biogenesis
S0042593biological_processglucose homeostasis
S0043065biological_processpositive regulation of apoptotic process
S0043066biological_processnegative regulation of apoptotic process
S0044297cellular_componentcell body
S0048471cellular_componentperinuclear region of cytoplasm
S0048821biological_processerythrocyte development
S1990904cellular_componentribonucleoprotein complex
T0002181biological_processcytoplasmic translation
T0003723molecular_functionRNA binding
T0003735molecular_functionstructural constituent of ribosome
T0005634cellular_componentnucleus
T0005654cellular_componentnucleoplasm
T0005730cellular_componentnucleolus
T0005737cellular_componentcytoplasm
T0005783cellular_componentendoplasmic reticulum
T0005829cellular_componentcytosol
T0005840cellular_componentribosome
T0006364biological_processrRNA processing
T0006412biological_processtranslation
T0015935cellular_componentsmall ribosomal subunit
T0016020cellular_componentmembrane
T0022626cellular_componentcytosolic ribosome
T0022627cellular_componentcytosolic small ribosomal subunit
T0031369molecular_functiontranslation initiation factor binding
T0032040cellular_componentsmall-subunit processome
T0034101biological_processerythrocyte homeostasis
T0042274biological_processribosomal small subunit biogenesis
T0044391cellular_componentribosomal subunit
T1990904cellular_componentribonucleoprotein complex
V0000028biological_processribosomal small subunit assembly
V0002181biological_processcytoplasmic translation
V0003723molecular_functionRNA binding
V0003729molecular_functionmRNA binding
V0003735molecular_functionstructural constituent of ribosome
V0005515molecular_functionprotein binding
V0005634cellular_componentnucleus
V0005654cellular_componentnucleoplasm
V0005730cellular_componentnucleolus
V0005737cellular_componentcytoplasm
V0005829cellular_componentcytosol
V0005840cellular_componentribosome
V0005925cellular_componentfocal adhesion
V0006412biological_processtranslation
V0006413biological_processtranslational initiation
V0006450biological_processregulation of translational fidelity
V0015935cellular_componentsmall ribosomal subunit
V0016020cellular_componentmembrane
V0019843molecular_functionrRNA binding
V0022626cellular_componentcytosolic ribosome
V0022627cellular_componentcytosolic small ribosomal subunit
V0032040cellular_componentsmall-subunit processome
V0042274biological_processribosomal small subunit biogenesis
V0045202cellular_componentsynapse
V0070062cellular_componentextracellular exosome
V1990904cellular_componentribonucleoprotein complex
Y0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
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x0001732biological_processformation of cytoplasmic translation initiation complex
x0002191biological_processcap-dependent translational initiation
x0003723molecular_functionRNA binding
x0003743molecular_functiontranslation initiation factor activity
x0005515molecular_functionprotein binding
x0005737cellular_componentcytoplasm
x0005829cellular_componentcytosol
x0005852cellular_componenteukaryotic translation initiation factor 3 complex
x0006412biological_processtranslation
x0006413biological_processtranslational initiation
x0016020cellular_componentmembrane
x0016282cellular_componenteukaryotic 43S preinitiation complex
x0033290cellular_componenteukaryotic 48S preinitiation complex
x0045202cellular_componentsynapse
x0045727biological_processpositive regulation of translation
x0071541cellular_componenteukaryotic translation initiation factor 3 complex, eIF3m
x0075522biological_processIRES-dependent viral translational initiation
x0075525biological_processviral translational termination-reinitiation
x0098808molecular_functionmRNA cap binding
x1902416biological_processpositive regulation of mRNA binding
y0001732biological_processformation of cytoplasmic translation initiation complex
y0002183biological_processcytoplasmic translational initiation
y0003723molecular_functionRNA binding
y0003743molecular_functiontranslation initiation factor activity
y0005515molecular_functionprotein binding
y0005737cellular_componentcytoplasm
y0005829cellular_componentcytosol
y0005852cellular_componenteukaryotic translation initiation factor 3 complex
y0006412biological_processtranslation
y0006413biological_processtranslational initiation
y0016282cellular_componenteukaryotic 43S preinitiation complex
y0031369molecular_functiontranslation initiation factor binding
y0032991cellular_componentprotein-containing complex
y0033290cellular_componenteukaryotic 48S preinitiation complex
y0043022molecular_functionribosome binding
y0045727biological_processpositive regulation of translation
y1902416biological_processpositive regulation of mRNA binding
Functional Information from PROSITE/UniProt
site_idPS00052
Number of Residues27
DetailsRIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA
ChainResidueDetails
VGLU70-ALA96

site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR
ChainResidueDetails
JGLY100-ARG117

site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD
ChainResidueDetails
PLEU116-ASP138

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR
ChainResidueDetails
ELYS60-ARG67

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS
ChainResidueDetails
BGLY123-SER135

site_idPS00299
Number of Residues26
DetailsUBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD
ChainResidueDetails
kLYS27-ASP52

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT
ChainResidueDetails
bASN98-THR122

site_idPS00360
Number of Residues19
DetailsRIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL
ChainResidueDetails
YGLY74-LEU92

site_idPS00361
Number of Residues16
DetailsRIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT
ChainResidueDetails
hALA43-THR58

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY
ChainResidueDetails
IVAL98-TYR128

site_idPS00527
Number of Residues23
DetailsRIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR
ChainResidueDetails
iARG22-ARG44

site_idPS00528
Number of Residues15
DetailsRIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK
ChainResidueDetails
CHIS8-LYS22

site_idPS00529
Number of Residues23
DetailsRIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE
ChainResidueDetails
TPHE64-GLU86

site_idPS00548
Number of Residues37
DetailsRIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG
ChainResidueDetails
ZALA147-GLY183

site_idPS00578
Number of Residues12
DetailsRIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM
ChainResidueDetails
SILE52-MET63

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI
ChainResidueDetails
LGLY119-ILE151

site_idPS00628
Number of Residues20
DetailsRIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE
ChainResidueDetails
dPRO89-GLU108

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI
ChainResidueDetails
DLEU106-ILE130

site_idPS00646
Number of Residues14
DetailsRIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ
ChainResidueDetails
fARG121-GLN134

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL
ChainResidueDetails
cALA78-LEU92
cILE120-THR134
cILE165-LEU179
cCYS207-LEU221

site_idPS00712
Number of Residues16
DetailsRIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH
ChainResidueDetails
MILE41-HIS56

site_idPS00733
Number of Residues8
DetailsRIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH
ChainResidueDetails
QTYR73-HIS80

site_idPS00948
Number of Residues14
DetailsRIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH
ChainResidueDetails
GARG78-HIS91

site_idPS00961
Number of Residues9
DetailsRIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL
ChainResidueDetails
nGLU60-LEU68

site_idPS00962
Number of Residues12
DetailsRIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG
ChainResidueDetails
NVAL15-GLY26

site_idPS00963
Number of Residues25
DetailsRIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP
ChainResidueDetails
NPRO119-PRO143

site_idPS00996
Number of Residues9
DetailsRIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA
ChainResidueDetails
KLEU11-ALA19

site_idPS01168
Number of Residues33
DetailsRIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG
ChainResidueDetails
HLYS36-GLY68

site_idPS01189
Number of Residues19
DetailsRIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI
ChainResidueDetails
mALA17-ILE35

site_idPS01191
Number of Residues13
DetailsRIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVfEvSLaDL
ChainResidueDetails
OLEU62-LEU74

site_idPS01193
Number of Residues20
DetailsRIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG
ChainResidueDetails
RARG11-GLY30

site_idPS01262
Number of Residues23
DetailsIF1A Eukaryotic initiation factor 1A signature. MlGnGRleamCfDGvkRlcHIrG
ChainResidueDetails
qMET41-GLY63

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsMOD_RES: Phosphoserine => ECO:0000255|HAMAP-Rule:MF_03002, ECO:0000269|PubMed:17322308
ChainResidueDetails
ySER9
ySER11
ySER13
ySER15
ySER16
ySER18
ySER39
ySER166
ySER909

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8R1B4
ChainResidueDetails
yLYS99
yLYS643
HCYS56
HCYS59

site_idSWS_FT_FI3
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8R1B4
ChainResidueDetails
ySER178
ySER181
ySER182
uSER1028
uSER1188
uSER1262

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000255|HAMAP-Rule:MF_03002, ECO:0000269|PubMed:17322308
ChainResidueDetails
yTHR524
uSER1198
uSER1336
PLYS106

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P60229
ChainResidueDetails
vTYR445
rTHR281
aLYS139

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000255|HAMAP-Rule:MF_03000, ECO:0000269|PubMed:17322308
ChainResidueDetails
uSER1364
ZARG65
ZARG67

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
ChainResidueDetails
sTHR111
kLYS113

site_idSWS_FT_FI8
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231
ChainResidueDetails
sSER158
LLYS275
1LYS364

site_idSWS_FT_FI9
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P41035
ChainResidueDetails
sSER218
SSER247

site_idSWS_FT_FI10
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
sLYS265
sLYS293

site_idSWS_FT_FI11
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
sLYS102
kLYS48

site_idSWS_FT_FI12
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860
ChainResidueDetails
kLYS27

site_idSWS_FT_FI13
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127
ChainResidueDetails
kLYS29

site_idSWS_FT_FI14
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577
ChainResidueDetails
kLYS33
ZLYS202

site_idSWS_FT_FI15
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106
ChainResidueDetails
kLYS63
ZLYS230

site_idSWS_FT_FI16
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
ChainResidueDetails
kGLY76

site_idSWS_FT_FI17
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36638793
ChainResidueDetails
kLYS107

227111

PDB entries from 2024-11-06

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