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7QJE

Structure of recombinant human gamma-Tubulin Ring Complex 4-spoked assembly intermediate (spokes 9-12)

Functional Information from GO Data
ChainGOidnamespacecontents
I0000226biological_processmicrotubule cytoskeleton organization
I0000278biological_processmitotic cell cycle
I0000922cellular_componentspindle pole
I0000923cellular_componentequatorial microtubule organizing center
I0000930cellular_componentgamma-tubulin complex
I0000931cellular_componentgamma-tubulin ring complex
I0005200molecular_functionstructural constituent of cytoskeleton
I0005515molecular_functionprotein binding
I0005737cellular_componentcytoplasm
I0005813cellular_componentcentrosome
I0005815cellular_componentmicrotubule organizing center
I0005829cellular_componentcytosol
I0005856cellular_componentcytoskeleton
I0005874cellular_componentmicrotubule
I0007020biological_processmicrotubule nucleation
I0015630cellular_componentmicrotubule cytoskeleton
I0016020cellular_componentmembrane
I0031122biological_processcytoplasmic microtubule organization
I0043015molecular_functiongamma-tubulin binding
I0051011molecular_functionmicrotubule minus-end binding
I0051225biological_processspindle assembly
I0051321biological_processmeiotic cell cycle
I0055037cellular_componentrecycling endosome
I0065003biological_processprotein-containing complex assembly
J0000226biological_processmicrotubule cytoskeleton organization
J0000278biological_processmitotic cell cycle
J0000922cellular_componentspindle pole
J0000923cellular_componentequatorial microtubule organizing center
J0000930cellular_componentgamma-tubulin complex
J0000931cellular_componentgamma-tubulin ring complex
J0005515molecular_functionprotein binding
J0005737cellular_componentcytoplasm
J0005813cellular_componentcentrosome
J0005815cellular_componentmicrotubule organizing center
J0005829cellular_componentcytosol
J0005856cellular_componentcytoskeleton
J0005874cellular_componentmicrotubule
J0007020biological_processmicrotubule nucleation
J0008017molecular_functionmicrotubule binding
J0031122biological_processcytoplasmic microtubule organization
J0043015molecular_functiongamma-tubulin binding
J0051011molecular_functionmicrotubule minus-end binding
J0051225biological_processspindle assembly
J0051321biological_processmeiotic cell cycle
K0000226biological_processmicrotubule cytoskeleton organization
K0000278biological_processmitotic cell cycle
K0000922cellular_componentspindle pole
K0000923cellular_componentequatorial microtubule organizing center
K0000930cellular_componentgamma-tubulin complex
K0000931cellular_componentgamma-tubulin ring complex
K0005200molecular_functionstructural constituent of cytoskeleton
K0005515molecular_functionprotein binding
K0005737cellular_componentcytoplasm
K0005813cellular_componentcentrosome
K0005815cellular_componentmicrotubule organizing center
K0005829cellular_componentcytosol
K0005856cellular_componentcytoskeleton
K0005874cellular_componentmicrotubule
K0007020biological_processmicrotubule nucleation
K0015630cellular_componentmicrotubule cytoskeleton
K0016020cellular_componentmembrane
K0031122biological_processcytoplasmic microtubule organization
K0043015molecular_functiongamma-tubulin binding
K0051011molecular_functionmicrotubule minus-end binding
K0051225biological_processspindle assembly
K0051321biological_processmeiotic cell cycle
K0055037cellular_componentrecycling endosome
K0065003biological_processprotein-containing complex assembly
L0000226biological_processmicrotubule cytoskeleton organization
L0000278biological_processmitotic cell cycle
L0000922cellular_componentspindle pole
L0000923cellular_componentequatorial microtubule organizing center
L0000930cellular_componentgamma-tubulin complex
L0000931cellular_componentgamma-tubulin ring complex
L0005737cellular_componentcytoplasm
L0005813cellular_componentcentrosome
L0005815cellular_componentmicrotubule organizing center
L0005829cellular_componentcytosol
L0005856cellular_componentcytoskeleton
L0005874cellular_componentmicrotubule
L0007020biological_processmicrotubule nucleation
L0008017molecular_functionmicrotubule binding
L0016020cellular_componentmembrane
L0031122biological_processcytoplasmic microtubule organization
L0043015molecular_functiongamma-tubulin binding
L0051011molecular_functionmicrotubule minus-end binding
L0051225biological_processspindle assembly
L0051321biological_processmeiotic cell cycle
W0000070biological_processmitotic sister chromatid segregation
W0000212biological_processmeiotic spindle organization
W0000226biological_processmicrotubule cytoskeleton organization
W0000242cellular_componentpericentriolar material
W0000278biological_processmitotic cell cycle
W0000794cellular_componentcondensed nuclear chromosome
W0000930cellular_componentgamma-tubulin complex
W0005200molecular_functionstructural constituent of cytoskeleton
W0005515molecular_functionprotein binding
W0005525molecular_functionGTP binding
W0005634cellular_componentnucleus
W0005737cellular_componentcytoplasm
W0005813cellular_componentcentrosome
W0005814cellular_componentcentriole
W0005819cellular_componentspindle
W0005827cellular_componentpolar microtubule
W0005829cellular_componentcytosol
W0005856cellular_componentcytoskeleton
W0005874cellular_componentmicrotubule
W0005876cellular_componentspindle microtubule
W0005881cellular_componentcytoplasmic microtubule
W0005929cellular_componentcilium
W0007017biological_processmicrotubule-based process
W0007020biological_processmicrotubule nucleation
W0007052biological_processmitotic spindle organization
W0015630cellular_componentmicrotubule cytoskeleton
W0031122biological_processcytoplasmic microtubule organization
W0031252cellular_componentcell leading edge
W0036064cellular_componentciliary basal body
W0042802molecular_functionidentical protein binding
W0043005cellular_componentneuron projection
W0045177cellular_componentapical part of cell
W0055037cellular_componentrecycling endosome
W0097730cellular_componentnon-motile cilium
W1990498cellular_componentmitotic spindle microtubule
X0000070biological_processmitotic sister chromatid segregation
X0000212biological_processmeiotic spindle organization
X0000226biological_processmicrotubule cytoskeleton organization
X0000242cellular_componentpericentriolar material
X0000278biological_processmitotic cell cycle
X0000794cellular_componentcondensed nuclear chromosome
X0000930cellular_componentgamma-tubulin complex
X0005200molecular_functionstructural constituent of cytoskeleton
X0005515molecular_functionprotein binding
X0005525molecular_functionGTP binding
X0005634cellular_componentnucleus
X0005737cellular_componentcytoplasm
X0005813cellular_componentcentrosome
X0005814cellular_componentcentriole
X0005819cellular_componentspindle
X0005827cellular_componentpolar microtubule
X0005829cellular_componentcytosol
X0005856cellular_componentcytoskeleton
X0005874cellular_componentmicrotubule
X0005876cellular_componentspindle microtubule
X0005881cellular_componentcytoplasmic microtubule
X0005929cellular_componentcilium
X0007017biological_processmicrotubule-based process
X0007020biological_processmicrotubule nucleation
X0007052biological_processmitotic spindle organization
X0015630cellular_componentmicrotubule cytoskeleton
X0031122biological_processcytoplasmic microtubule organization
X0031252cellular_componentcell leading edge
X0036064cellular_componentciliary basal body
X0042802molecular_functionidentical protein binding
X0043005cellular_componentneuron projection
X0045177cellular_componentapical part of cell
X0055037cellular_componentrecycling endosome
X0097730cellular_componentnon-motile cilium
X1990498cellular_componentmitotic spindle microtubule
Y0000070biological_processmitotic sister chromatid segregation
Y0000212biological_processmeiotic spindle organization
Y0000226biological_processmicrotubule cytoskeleton organization
Y0000242cellular_componentpericentriolar material
Y0000278biological_processmitotic cell cycle
Y0000794cellular_componentcondensed nuclear chromosome
Y0000930cellular_componentgamma-tubulin complex
Y0005200molecular_functionstructural constituent of cytoskeleton
Y0005515molecular_functionprotein binding
Y0005525molecular_functionGTP binding
Y0005634cellular_componentnucleus
Y0005737cellular_componentcytoplasm
Y0005813cellular_componentcentrosome
Y0005814cellular_componentcentriole
Y0005819cellular_componentspindle
Y0005827cellular_componentpolar microtubule
Y0005829cellular_componentcytosol
Y0005856cellular_componentcytoskeleton
Y0005874cellular_componentmicrotubule
Y0005876cellular_componentspindle microtubule
Y0005881cellular_componentcytoplasmic microtubule
Y0005929cellular_componentcilium
Y0007017biological_processmicrotubule-based process
Y0007020biological_processmicrotubule nucleation
Y0007052biological_processmitotic spindle organization
Y0015630cellular_componentmicrotubule cytoskeleton
Y0031122biological_processcytoplasmic microtubule organization
Y0031252cellular_componentcell leading edge
Y0036064cellular_componentciliary basal body
Y0042802molecular_functionidentical protein binding
Y0043005cellular_componentneuron projection
Y0045177cellular_componentapical part of cell
Y0055037cellular_componentrecycling endosome
Y0097730cellular_componentnon-motile cilium
Y1990498cellular_componentmitotic spindle microtubule
Z0000070biological_processmitotic sister chromatid segregation
Z0000212biological_processmeiotic spindle organization
Z0000226biological_processmicrotubule cytoskeleton organization
Z0000242cellular_componentpericentriolar material
Z0000278biological_processmitotic cell cycle
Z0000794cellular_componentcondensed nuclear chromosome
Z0000930cellular_componentgamma-tubulin complex
Z0005200molecular_functionstructural constituent of cytoskeleton
Z0005515molecular_functionprotein binding
Z0005525molecular_functionGTP binding
Z0005634cellular_componentnucleus
Z0005737cellular_componentcytoplasm
Z0005813cellular_componentcentrosome
Z0005814cellular_componentcentriole
Z0005819cellular_componentspindle
Z0005827cellular_componentpolar microtubule
Z0005829cellular_componentcytosol
Z0005856cellular_componentcytoskeleton
Z0005874cellular_componentmicrotubule
Z0005876cellular_componentspindle microtubule
Z0005881cellular_componentcytoplasmic microtubule
Z0005929cellular_componentcilium
Z0007017biological_processmicrotubule-based process
Z0007020biological_processmicrotubule nucleation
Z0007052biological_processmitotic spindle organization
Z0015630cellular_componentmicrotubule cytoskeleton
Z0031122biological_processcytoplasmic microtubule organization
Z0031252cellular_componentcell leading edge
Z0036064cellular_componentciliary basal body
Z0042802molecular_functionidentical protein binding
Z0043005cellular_componentneuron projection
Z0045177cellular_componentapical part of cell
Z0055037cellular_componentrecycling endosome
Z0097730cellular_componentnon-motile cilium
Z1990498cellular_componentmitotic spindle microtubule
Functional Information from PROSITE/UniProt
site_idPS00227
Number of Residues7
DetailsTUBULIN Tubulin subunits alpha, beta, and gamma signature. AGGTGSG
ChainResidueDetails
WALA142-GLY148

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000255
ChainResidueDetails
WALA142
XALA142
YALA142
ZALA142

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: Phosphoserine; by BRSK1 => ECO:0000250|UniProtKB:P83887
ChainResidueDetails
WSER131
XSER131
YSER131
ZSER131

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PDB entries from 2024-07-24

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