7QEY

human Connexin 26 class 1 hexamer at 90mmHg PCO2, pH7.4

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0005922	cellular_component	connexin complex
G	0007154	biological_process	cell communication
H	0005922	cellular_component	connexin complex
H	0007154	biological_process	cell communication
I	0005922	cellular_component	connexin complex
I	0007154	biological_process	cell communication
J	0005922	cellular_component	connexin complex
J	0007154	biological_process	cell communication
K	0005922	cellular_component	connexin complex
K	0007154	biological_process	cell communication
L	0005922	cellular_component	connexin complex
L	0007154	biological_process	cell communication

Functional Information from PROSITE/UniProt

site_id	PS00407
Number of Residues	14
Details	CONNEXINS_1 Connexins signature 1. CNTlQPGCknVCYD

Chain	Residue	Details
G	CYS53-ASP66

---

site_id	PS00408
Number of Residues	17
Details	CONNEXINS_2 Connexins signature 2. Cnaw.PCpntVDCFVSRP

Chain	Residue	Details
G	CYS169-PRO185

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"26753910","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	474
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"26753910","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	384
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"26753910","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"26753910","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5ER7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26753910","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5ER7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---