7QB9
Structure of the ligand-free GPCR dimer Ste2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000750 | biological_process | pheromone-dependent signal transduction involved in conjugation with cellular fusion |
| A | 0000755 | biological_process | cytogamy |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0004932 | molecular_function | mating-type factor pheromone receptor activity |
| A | 0004934 | molecular_function | mating-type alpha-factor pheromone receptor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007165 | biological_process | signal transduction |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
| A | 0019236 | biological_process | response to pheromone |
| A | 0038038 | cellular_component | G protein-coupled receptor homodimeric complex |
| B | 0000750 | biological_process | pheromone-dependent signal transduction involved in conjugation with cellular fusion |
| B | 0000755 | biological_process | cytogamy |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0004932 | molecular_function | mating-type factor pheromone receptor activity |
| B | 0004934 | molecular_function | mating-type alpha-factor pheromone receptor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007165 | biological_process | signal transduction |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0016020 | cellular_component | membrane |
| B | 0019236 | biological_process | response to pheromone |
| B | 0038038 | cellular_component | G protein-coupled receptor homodimeric complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 44 |
| Details | Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"11112532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11467956","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19383463","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2K9P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 42 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"1653030","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"2017168","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"11112532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11467956","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19383463","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2K9P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 106 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"1653030","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"2017168","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"11112532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11467956","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 48 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"11112532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11467956","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 48 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"11112532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11467956","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 48 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"11112532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11467956","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11473349","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1PJD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 46 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"11112532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11467956","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 16 |
| Details | Motif: {"description":"Glycine zipper motif","evidences":[{"source":"PubMed","id":"14506226","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33268889","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 308 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
