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7Q69

Crystal structure of Chaetomium thermophilum C30S Ahp1 in the pre-reaction state

Functional Information from GO Data
ChainGOidnamespacecontents
A0004601molecular_functionperoxidase activity
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005777cellular_componentperoxisome
A0008379molecular_functionthioredoxin peroxidase activity
A0016209molecular_functionantioxidant activity
A0016491molecular_functionoxidoreductase activity
A0034599biological_processcellular response to oxidative stress
A0042744biological_processhydrogen peroxide catabolic process
A0045454biological_processcell redox homeostasis
A0046872molecular_functionmetal ion binding
A0098869biological_processcellular oxidant detoxification
A0140824molecular_functionthioredoxin-dependent peroxiredoxin activity
B0004601molecular_functionperoxidase activity
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005777cellular_componentperoxisome
B0008379molecular_functionthioredoxin peroxidase activity
B0016209molecular_functionantioxidant activity
B0016491molecular_functionoxidoreductase activity
B0034599biological_processcellular response to oxidative stress
B0042744biological_processhydrogen peroxide catabolic process
B0045454biological_processcell redox homeostasis
B0046872molecular_functionmetal ion binding
B0098869biological_processcellular oxidant detoxification
B0140824molecular_functionthioredoxin-dependent peroxiredoxin activity
C0004601molecular_functionperoxidase activity
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005777cellular_componentperoxisome
C0008379molecular_functionthioredoxin peroxidase activity
C0016209molecular_functionantioxidant activity
C0016491molecular_functionoxidoreductase activity
C0034599biological_processcellular response to oxidative stress
C0042744biological_processhydrogen peroxide catabolic process
C0045454biological_processcell redox homeostasis
C0046872molecular_functionmetal ion binding
C0098869biological_processcellular oxidant detoxification
C0140824molecular_functionthioredoxin-dependent peroxiredoxin activity
D0004601molecular_functionperoxidase activity
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005777cellular_componentperoxisome
D0008379molecular_functionthioredoxin peroxidase activity
D0016209molecular_functionantioxidant activity
D0016491molecular_functionoxidoreductase activity
D0034599biological_processcellular response to oxidative stress
D0042744biological_processhydrogen peroxide catabolic process
D0045454biological_processcell redox homeostasis
D0046872molecular_functionmetal ion binding
D0098869biological_processcellular oxidant detoxification
D0140824molecular_functionthioredoxin-dependent peroxiredoxin activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000250|UniProtKB:P38013
ChainResidueDetails
ACYS60
BCYS60
CCYS60
DCYS60

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: Cysteine persulfide => ECO:0000269|PubMed:36102610
ChainResidueDetails
ACYS60
BCYS60
CCYS60
DCYS60

site_idSWS_FT_FI3
Number of Residues28
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in URM1) => ECO:0000269|PubMed:36102610
ChainResidueDetails
ALYS44
BLYS63
BLYS99
BLYS141
BLYS156
BLYS171
CLYS44
CLYS63
CLYS99
CLYS141
CLYS156
CLYS171
DLYS44
DLYS63
DLYS99
DLYS141
DLYS156
DLYS171
ALYS63
ALYS99
ALYS141
ALYS156
ALYS171
BLYS44

238268

PDB entries from 2025-07-02

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