Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7Q5R

Protein community member pyruvate dehydrogenase complex E2 core from C. thermophilum

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
A	0005739	cellular_component	mitochondrion
A	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
A	0006090	biological_process	pyruvate metabolic process
A	0016746	molecular_function	acyltransferase activity
A	0045254	cellular_component	pyruvate dehydrogenase complex
AA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
AA	0005739	cellular_component	mitochondrion
AA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
AA	0006090	biological_process	pyruvate metabolic process
AA	0016746	molecular_function	acyltransferase activity
AA	0045254	cellular_component	pyruvate dehydrogenase complex
AB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
AB	0005739	cellular_component	mitochondrion
AB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
AB	0006090	biological_process	pyruvate metabolic process
AB	0016746	molecular_function	acyltransferase activity
AB	0045254	cellular_component	pyruvate dehydrogenase complex
B	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
B	0005739	cellular_component	mitochondrion
B	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
B	0006090	biological_process	pyruvate metabolic process
B	0016746	molecular_function	acyltransferase activity
B	0045254	cellular_component	pyruvate dehydrogenase complex
BA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
BA	0005739	cellular_component	mitochondrion
BA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
BA	0006090	biological_process	pyruvate metabolic process
BA	0016746	molecular_function	acyltransferase activity
BA	0045254	cellular_component	pyruvate dehydrogenase complex
BB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
BB	0005739	cellular_component	mitochondrion
BB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
BB	0006090	biological_process	pyruvate metabolic process
BB	0016746	molecular_function	acyltransferase activity
BB	0045254	cellular_component	pyruvate dehydrogenase complex
C	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
C	0005739	cellular_component	mitochondrion
C	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
C	0006090	biological_process	pyruvate metabolic process
C	0016746	molecular_function	acyltransferase activity
C	0045254	cellular_component	pyruvate dehydrogenase complex
CA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
CA	0005739	cellular_component	mitochondrion
CA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
CA	0006090	biological_process	pyruvate metabolic process
CA	0016746	molecular_function	acyltransferase activity
CA	0045254	cellular_component	pyruvate dehydrogenase complex
CB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
CB	0005739	cellular_component	mitochondrion
CB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
CB	0006090	biological_process	pyruvate metabolic process
CB	0016746	molecular_function	acyltransferase activity
CB	0045254	cellular_component	pyruvate dehydrogenase complex
D	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
D	0005739	cellular_component	mitochondrion
D	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
D	0006090	biological_process	pyruvate metabolic process
D	0016746	molecular_function	acyltransferase activity
D	0045254	cellular_component	pyruvate dehydrogenase complex
DA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
DA	0005739	cellular_component	mitochondrion
DA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
DA	0006090	biological_process	pyruvate metabolic process
DA	0016746	molecular_function	acyltransferase activity
DA	0045254	cellular_component	pyruvate dehydrogenase complex
DB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
DB	0005739	cellular_component	mitochondrion
DB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
DB	0006090	biological_process	pyruvate metabolic process
DB	0016746	molecular_function	acyltransferase activity
DB	0045254	cellular_component	pyruvate dehydrogenase complex
E	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
E	0005739	cellular_component	mitochondrion
E	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
E	0006090	biological_process	pyruvate metabolic process
E	0016746	molecular_function	acyltransferase activity
E	0045254	cellular_component	pyruvate dehydrogenase complex
EA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
EA	0005739	cellular_component	mitochondrion
EA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
EA	0006090	biological_process	pyruvate metabolic process
EA	0016746	molecular_function	acyltransferase activity
EA	0045254	cellular_component	pyruvate dehydrogenase complex
EB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
EB	0005739	cellular_component	mitochondrion
EB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
EB	0006090	biological_process	pyruvate metabolic process
EB	0016746	molecular_function	acyltransferase activity
EB	0045254	cellular_component	pyruvate dehydrogenase complex
F	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
F	0005739	cellular_component	mitochondrion
F	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
F	0006090	biological_process	pyruvate metabolic process
F	0016746	molecular_function	acyltransferase activity
F	0045254	cellular_component	pyruvate dehydrogenase complex
FA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
FA	0005739	cellular_component	mitochondrion
FA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
FA	0006090	biological_process	pyruvate metabolic process
FA	0016746	molecular_function	acyltransferase activity
FA	0045254	cellular_component	pyruvate dehydrogenase complex
FB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
FB	0005739	cellular_component	mitochondrion
FB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
FB	0006090	biological_process	pyruvate metabolic process
FB	0016746	molecular_function	acyltransferase activity
FB	0045254	cellular_component	pyruvate dehydrogenase complex
G	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
G	0005739	cellular_component	mitochondrion
G	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
G	0006090	biological_process	pyruvate metabolic process
G	0016746	molecular_function	acyltransferase activity
G	0045254	cellular_component	pyruvate dehydrogenase complex
GA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
GA	0005739	cellular_component	mitochondrion
GA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
GA	0006090	biological_process	pyruvate metabolic process
GA	0016746	molecular_function	acyltransferase activity
GA	0045254	cellular_component	pyruvate dehydrogenase complex
GB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
GB	0005739	cellular_component	mitochondrion
GB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
GB	0006090	biological_process	pyruvate metabolic process
GB	0016746	molecular_function	acyltransferase activity
GB	0045254	cellular_component	pyruvate dehydrogenase complex
H	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
H	0005739	cellular_component	mitochondrion
H	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
H	0006090	biological_process	pyruvate metabolic process
H	0016746	molecular_function	acyltransferase activity
H	0045254	cellular_component	pyruvate dehydrogenase complex
HA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
HA	0005739	cellular_component	mitochondrion
HA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
HA	0006090	biological_process	pyruvate metabolic process
HA	0016746	molecular_function	acyltransferase activity
HA	0045254	cellular_component	pyruvate dehydrogenase complex
HB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
HB	0005739	cellular_component	mitochondrion
HB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
HB	0006090	biological_process	pyruvate metabolic process
HB	0016746	molecular_function	acyltransferase activity
HB	0045254	cellular_component	pyruvate dehydrogenase complex
I	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
I	0005739	cellular_component	mitochondrion
I	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
I	0006090	biological_process	pyruvate metabolic process
I	0016746	molecular_function	acyltransferase activity
I	0045254	cellular_component	pyruvate dehydrogenase complex
IA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
IA	0005739	cellular_component	mitochondrion
IA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
IA	0006090	biological_process	pyruvate metabolic process
IA	0016746	molecular_function	acyltransferase activity
IA	0045254	cellular_component	pyruvate dehydrogenase complex
IB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
IB	0005739	cellular_component	mitochondrion
IB	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
IB	0006090	biological_process	pyruvate metabolic process
IB	0016746	molecular_function	acyltransferase activity
IB	0045254	cellular_component	pyruvate dehydrogenase complex
J	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
J	0005739	cellular_component	mitochondrion
J	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
J	0006090	biological_process	pyruvate metabolic process
J	0016746	molecular_function	acyltransferase activity
J	0045254	cellular_component	pyruvate dehydrogenase complex
JA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
JA	0005739	cellular_component	mitochondrion
JA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
JA	0006090	biological_process	pyruvate metabolic process
JA	0016746	molecular_function	acyltransferase activity
JA	0045254	cellular_component	pyruvate dehydrogenase complex
K	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
K	0005739	cellular_component	mitochondrion
K	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
K	0006090	biological_process	pyruvate metabolic process
K	0016746	molecular_function	acyltransferase activity
K	0045254	cellular_component	pyruvate dehydrogenase complex
KA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
KA	0005739	cellular_component	mitochondrion
KA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
KA	0006090	biological_process	pyruvate metabolic process
KA	0016746	molecular_function	acyltransferase activity
KA	0045254	cellular_component	pyruvate dehydrogenase complex
L	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
L	0005739	cellular_component	mitochondrion
L	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
L	0006090	biological_process	pyruvate metabolic process
L	0016746	molecular_function	acyltransferase activity
L	0045254	cellular_component	pyruvate dehydrogenase complex
LA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
LA	0005739	cellular_component	mitochondrion
LA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
LA	0006090	biological_process	pyruvate metabolic process
LA	0016746	molecular_function	acyltransferase activity
LA	0045254	cellular_component	pyruvate dehydrogenase complex
M	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
M	0005739	cellular_component	mitochondrion
M	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
M	0006090	biological_process	pyruvate metabolic process
M	0016746	molecular_function	acyltransferase activity
M	0045254	cellular_component	pyruvate dehydrogenase complex
MA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
MA	0005739	cellular_component	mitochondrion
MA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
MA	0006090	biological_process	pyruvate metabolic process
MA	0016746	molecular_function	acyltransferase activity
MA	0045254	cellular_component	pyruvate dehydrogenase complex
N	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
N	0005739	cellular_component	mitochondrion
N	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
N	0006090	biological_process	pyruvate metabolic process
N	0016746	molecular_function	acyltransferase activity
N	0045254	cellular_component	pyruvate dehydrogenase complex
NA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
NA	0005739	cellular_component	mitochondrion
NA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
NA	0006090	biological_process	pyruvate metabolic process
NA	0016746	molecular_function	acyltransferase activity
NA	0045254	cellular_component	pyruvate dehydrogenase complex
O	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
O	0005739	cellular_component	mitochondrion
O	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
O	0006090	biological_process	pyruvate metabolic process
O	0016746	molecular_function	acyltransferase activity
O	0045254	cellular_component	pyruvate dehydrogenase complex
OA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
OA	0005739	cellular_component	mitochondrion
OA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
OA	0006090	biological_process	pyruvate metabolic process
OA	0016746	molecular_function	acyltransferase activity
OA	0045254	cellular_component	pyruvate dehydrogenase complex
P	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
P	0005739	cellular_component	mitochondrion
P	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
P	0006090	biological_process	pyruvate metabolic process
P	0016746	molecular_function	acyltransferase activity
P	0045254	cellular_component	pyruvate dehydrogenase complex
PA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
PA	0005739	cellular_component	mitochondrion
PA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
PA	0006090	biological_process	pyruvate metabolic process
PA	0016746	molecular_function	acyltransferase activity
PA	0045254	cellular_component	pyruvate dehydrogenase complex
Q	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
Q	0005739	cellular_component	mitochondrion
Q	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
Q	0006090	biological_process	pyruvate metabolic process
Q	0016746	molecular_function	acyltransferase activity
Q	0045254	cellular_component	pyruvate dehydrogenase complex
QA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
QA	0005739	cellular_component	mitochondrion
QA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
QA	0006090	biological_process	pyruvate metabolic process
QA	0016746	molecular_function	acyltransferase activity
QA	0045254	cellular_component	pyruvate dehydrogenase complex
R	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
R	0005739	cellular_component	mitochondrion
R	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
R	0006090	biological_process	pyruvate metabolic process
R	0016746	molecular_function	acyltransferase activity
R	0045254	cellular_component	pyruvate dehydrogenase complex
RA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
RA	0005739	cellular_component	mitochondrion
RA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
RA	0006090	biological_process	pyruvate metabolic process
RA	0016746	molecular_function	acyltransferase activity
RA	0045254	cellular_component	pyruvate dehydrogenase complex
S	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
S	0005739	cellular_component	mitochondrion
S	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
S	0006090	biological_process	pyruvate metabolic process
S	0016746	molecular_function	acyltransferase activity
S	0045254	cellular_component	pyruvate dehydrogenase complex
SA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
SA	0005739	cellular_component	mitochondrion
SA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
SA	0006090	biological_process	pyruvate metabolic process
SA	0016746	molecular_function	acyltransferase activity
SA	0045254	cellular_component	pyruvate dehydrogenase complex
T	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
T	0005739	cellular_component	mitochondrion
T	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
T	0006090	biological_process	pyruvate metabolic process
T	0016746	molecular_function	acyltransferase activity
T	0045254	cellular_component	pyruvate dehydrogenase complex
TA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
TA	0005739	cellular_component	mitochondrion
TA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
TA	0006090	biological_process	pyruvate metabolic process
TA	0016746	molecular_function	acyltransferase activity
TA	0045254	cellular_component	pyruvate dehydrogenase complex
UA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
UA	0005739	cellular_component	mitochondrion
UA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
UA	0006090	biological_process	pyruvate metabolic process
UA	0016746	molecular_function	acyltransferase activity
UA	0045254	cellular_component	pyruvate dehydrogenase complex
V	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
V	0005739	cellular_component	mitochondrion
V	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
V	0006090	biological_process	pyruvate metabolic process
V	0016746	molecular_function	acyltransferase activity
V	0045254	cellular_component	pyruvate dehydrogenase complex
VA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
VA	0005739	cellular_component	mitochondrion
VA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
VA	0006090	biological_process	pyruvate metabolic process
VA	0016746	molecular_function	acyltransferase activity
VA	0045254	cellular_component	pyruvate dehydrogenase complex
W	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
W	0005739	cellular_component	mitochondrion
W	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
W	0006090	biological_process	pyruvate metabolic process
W	0016746	molecular_function	acyltransferase activity
W	0045254	cellular_component	pyruvate dehydrogenase complex
WA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
WA	0005739	cellular_component	mitochondrion
WA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
WA	0006090	biological_process	pyruvate metabolic process
WA	0016746	molecular_function	acyltransferase activity
WA	0045254	cellular_component	pyruvate dehydrogenase complex
X	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
X	0005739	cellular_component	mitochondrion
X	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
X	0006090	biological_process	pyruvate metabolic process
X	0016746	molecular_function	acyltransferase activity
X	0045254	cellular_component	pyruvate dehydrogenase complex
XA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
XA	0005739	cellular_component	mitochondrion
XA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
XA	0006090	biological_process	pyruvate metabolic process
XA	0016746	molecular_function	acyltransferase activity
XA	0045254	cellular_component	pyruvate dehydrogenase complex
Y	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
Y	0005739	cellular_component	mitochondrion
Y	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
Y	0006090	biological_process	pyruvate metabolic process
Y	0016746	molecular_function	acyltransferase activity
Y	0045254	cellular_component	pyruvate dehydrogenase complex
YA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
YA	0005739	cellular_component	mitochondrion
YA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
YA	0006090	biological_process	pyruvate metabolic process
YA	0016746	molecular_function	acyltransferase activity
YA	0045254	cellular_component	pyruvate dehydrogenase complex
Z	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
Z	0005739	cellular_component	mitochondrion
Z	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
Z	0006090	biological_process	pyruvate metabolic process
Z	0016746	molecular_function	acyltransferase activity
Z	0045254	cellular_component	pyruvate dehydrogenase complex
ZA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
ZA	0005739	cellular_component	mitochondrion
ZA	0006086	biological_process	acetyl-CoA biosynthetic process from pyruvate
ZA	0006090	biological_process	pyruvate metabolic process
ZA	0016746	molecular_function	acyltransferase activity
ZA	0045254	cellular_component	pyruvate dehydrogenase complex

Functional Information from PROSITE/UniProt

site_id	PS00189
Number of Residues	30
Details	LIPOYL 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. GdaItpgEVLveIETdKAQmdFefqeeGvL

Chain	Residue	Details
A	GLY-170-LEU-141

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	360
Details	BINDING: BINDING => ECO:0000269\|PubMed:34836937, ECO:0007744\|PDB:7OTT

Chain	Residue	Details
A	ARG40
B	ARG128
Q	ARG128
Q	SER145
Q	ASN146
R	ARG40
R	SER54
R	ASN56
R	ARG128
R	SER145
R	ASN146
S	ARG40
B	SER145
S	SER54
S	ASN56
S	ARG128
S	SER145
S	ASN146
T	ARG40
T	SER54
T	ASN56
T	ARG128
T	SER145
B	ASN146
T	ASN146
V	ARG40
V	SER54
V	ASN56
V	ARG128
V	SER145
V	ASN146
W	ARG40
W	SER54
W	ASN56
C	ARG40
W	ARG128
W	SER145
W	ASN146
X	ARG40
X	SER54
X	ASN56
X	ARG128
X	SER145
X	ASN146
Y	ARG40
C	SER54
Y	SER54
Y	ASN56
Y	ARG128
Y	SER145
Y	ASN146
Z	ARG40
Z	SER54
Z	ASN56
Z	ARG128
Z	SER145
C	ASN56
Z	ASN146
AA	ARG40
AA	SER54
AA	ASN56
AA	ARG128
AA	SER145
AA	ASN146
BA	ARG40
BA	SER54
BA	ASN56
C	ARG128
BA	ARG128
BA	SER145
BA	ASN146
CA	ARG40
CA	SER54
CA	ASN56
CA	ARG128
CA	SER145
CA	ASN146
DA	ARG40
C	SER145
DA	SER54
DA	ASN56
DA	ARG128
DA	SER145
DA	ASN146
EA	ARG40
EA	SER54
EA	ASN56
EA	ARG128
EA	SER145
C	ASN146
EA	ASN146
FA	ARG40
FA	SER54
FA	ASN56
FA	ARG128
FA	SER145
FA	ASN146
GA	ARG40
GA	SER54
GA	ASN56
D	ARG40
GA	ARG128
GA	SER145
GA	ASN146
HA	ARG40
HA	SER54
HA	ASN56
HA	ARG128
HA	SER145
HA	ASN146
IA	ARG40
A	SER54
D	SER54
IA	SER54
IA	ASN56
IA	ARG128
IA	SER145
IA	ASN146
JA	ARG40
JA	SER54
JA	ASN56
JA	ARG128
JA	SER145
D	ASN56
JA	ASN146
KA	ARG40
KA	SER54
KA	ASN56
KA	ARG128
KA	SER145
KA	ASN146
LA	ARG40
LA	SER54
LA	ASN56
D	ARG128
LA	ARG128
LA	SER145
LA	ASN146
MA	ARG40
MA	SER54
MA	ASN56
MA	ARG128
MA	SER145
MA	ASN146
NA	ARG40
D	SER145
NA	SER54
NA	ASN56
NA	ARG128
NA	SER145
NA	ASN146
OA	ARG40
OA	SER54
OA	ASN56
OA	ARG128
OA	SER145
D	ASN146
OA	ASN146
PA	ARG40
PA	SER54
PA	ASN56
PA	ARG128
PA	SER145
PA	ASN146
QA	ARG40
QA	SER54
QA	ASN56
E	ARG40
QA	ARG128
QA	SER145
QA	ASN146
RA	ARG40
RA	SER54
RA	ASN56
RA	ARG128
RA	SER145
RA	ASN146
SA	ARG40
E	SER54
SA	SER54
SA	ASN56
SA	ARG128
SA	SER145
SA	ASN146
TA	ARG40
TA	SER54
TA	ASN56
TA	ARG128
TA	SER145
E	ASN56
TA	ASN146
UA	ARG40
UA	SER54
UA	ASN56
UA	ARG128
UA	SER145
UA	ASN146
VA	ARG40
VA	SER54
VA	ASN56
E	ARG128
VA	ARG128
VA	SER145
VA	ASN146
WA	ARG40
WA	SER54
WA	ASN56
WA	ARG128
WA	SER145
WA	ASN146
XA	ARG40
E	SER145
XA	SER54
XA	ASN56
XA	ARG128
XA	SER145
XA	ASN146
YA	ARG40
YA	SER54
YA	ASN56
YA	ARG128
YA	SER145
A	ASN56
E	ASN146
YA	ASN146
ZA	ARG40
ZA	SER54
ZA	ASN56
ZA	ARG128
ZA	SER145
ZA	ASN146
AB	ARG40
AB	SER54
AB	ASN56
F	ARG40
AB	ARG128
AB	SER145
AB	ASN146
BB	ARG40
BB	SER54
BB	ASN56
BB	ARG128
BB	SER145
BB	ASN146
CB	ARG40
F	SER54
CB	SER54
CB	ASN56
CB	ARG128
CB	SER145
CB	ASN146
DB	ARG40
DB	SER54
DB	ASN56
DB	ARG128
DB	SER145
F	ASN56
DB	ASN146
EB	ARG40
EB	SER54
EB	ASN56
EB	ARG128
EB	SER145
EB	ASN146
FB	ARG40
FB	SER54
FB	ASN56
F	ARG128
FB	ARG128
FB	SER145
FB	ASN146
GB	ARG40
GB	SER54
GB	ASN56
GB	ARG128
GB	SER145
GB	ASN146
HB	ARG40
F	SER145
HB	SER54
HB	ASN56
HB	ARG128
HB	SER145
HB	ASN146
IB	ARG40
IB	SER54
IB	ASN56
IB	ARG128
IB	SER145
F	ASN146
IB	ASN146
G	ARG40
G	SER54
G	ASN56
A	ARG128
G	ARG128
G	SER145
G	ASN146
H	ARG40
H	SER54
H	ASN56
H	ARG128
H	SER145
H	ASN146
I	ARG40
A	SER145
I	SER54
I	ASN56
I	ARG128
I	SER145
I	ASN146
J	ARG40
J	SER54
J	ASN56
J	ARG128
J	SER145
A	ASN146
J	ASN146
K	ARG40
K	SER54
K	ASN56
K	ARG128
K	SER145
K	ASN146
L	ARG40
L	SER54
L	ASN56
B	ARG40
L	ARG128
L	SER145
L	ASN146
M	ARG40
M	SER54
M	ASN56
M	ARG128
M	SER145
M	ASN146
N	ARG40
B	SER54
N	SER54
N	ASN56
N	ARG128
N	SER145
N	ASN146
O	ARG40
O	SER54
O	ASN56
O	ARG128
O	SER145
B	ASN56
O	ASN146
P	ARG40
P	SER54
P	ASN56
P	ARG128
P	SER145
P	ASN146
Q	ARG40
Q	SER54
Q	ASN56

site_id	SWS_FT_FI2
Number of Residues	60
Details	SITE: May form a delocalized pi-electron network with Arg-384 of 2 other E2 subunits within the complex, which greatly improves protein stability => ECO:0000269\|PubMed:34836937, ECO:0007744\|PDB:7OTT

Chain	Residue	Details
A	ARG155
J	ARG155
K	ARG155
L	ARG155
M	ARG155
N	ARG155
O	ARG155
P	ARG155
Q	ARG155
R	ARG155
S	ARG155
B	ARG155
T	ARG155
V	ARG155
W	ARG155
X	ARG155
Y	ARG155
Z	ARG155
AA	ARG155
BA	ARG155
CA	ARG155
DA	ARG155
C	ARG155
EA	ARG155
FA	ARG155
GA	ARG155
HA	ARG155
IA	ARG155
JA	ARG155
KA	ARG155
LA	ARG155
MA	ARG155
NA	ARG155
D	ARG155
OA	ARG155
PA	ARG155
QA	ARG155
RA	ARG155
SA	ARG155
TA	ARG155
UA	ARG155
VA	ARG155
WA	ARG155
XA	ARG155
E	ARG155
YA	ARG155
ZA	ARG155
AB	ARG155
BB	ARG155
CB	ARG155
DB	ARG155
EB	ARG155
FB	ARG155
GB	ARG155
HB	ARG155
F	ARG155
IB	ARG155
G	ARG155
H	ARG155
I	ARG155

site_id	SWS_FT_FI3
Number of Residues	60
Details	MOD_RES: N6-lipoyllysine => ECO:0000255\|PROSITE-ProRule:PRU01066

Chain	Residue	Details
A	LYS-154
J	LYS-154
K	LYS-154
L	LYS-154
M	LYS-154
N	LYS-154
O	LYS-154
P	LYS-154
Q	LYS-154
R	LYS-154
S	LYS-154
B	LYS-154
T	LYS-154
V	LYS-154
W	LYS-154
X	LYS-154
Y	LYS-154
Z	LYS-154
AA	LYS-154
BA	LYS-154
CA	LYS-154
DA	LYS-154
C	LYS-154
EA	LYS-154
FA	LYS-154
GA	LYS-154
HA	LYS-154
IA	LYS-154
JA	LYS-154
KA	LYS-154
LA	LYS-154
MA	LYS-154
NA	LYS-154
D	LYS-154
OA	LYS-154
PA	LYS-154
QA	LYS-154
RA	LYS-154
SA	LYS-154
TA	LYS-154
UA	LYS-154
VA	LYS-154
WA	LYS-154
XA	LYS-154
E	LYS-154
YA	LYS-154
ZA	LYS-154
AB	LYS-154
BB	LYS-154
CB	LYS-154
DB	LYS-154
EB	LYS-154
FB	LYS-154
GB	LYS-154
HB	LYS-154
F	LYS-154
IB	LYS-154
G	LYS-154
H	LYS-154
I	LYS-154

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)