7Q56

Single Particle Cryo-EM structure of photosynthetic A8B8 glyceraldehyde-3-phosphate dehydrogenase (minor conformer) from Spinacia oleracea.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006006	biological_process	glucose metabolic process
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
B	0006006	biological_process	glucose metabolic process
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding
C	0006006	biological_process	glucose metabolic process
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0050661	molecular_function	NADP binding
C	0051287	molecular_function	NAD binding
D	0006006	biological_process	glucose metabolic process
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0050661	molecular_function	NADP binding
D	0051287	molecular_function	NAD binding
E	0006006	biological_process	glucose metabolic process
E	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
E	0050661	molecular_function	NADP binding
E	0051287	molecular_function	NAD binding
F	0006006	biological_process	glucose metabolic process
F	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
F	0050661	molecular_function	NADP binding
F	0051287	molecular_function	NAD binding
G	0006006	biological_process	glucose metabolic process
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0050661	molecular_function	NADP binding
G	0051287	molecular_function	NAD binding
H	0006006	biological_process	glucose metabolic process
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0050661	molecular_function	NADP binding
H	0051287	molecular_function	NAD binding
I	0006006	biological_process	glucose metabolic process
I	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
I	0050661	molecular_function	NADP binding
I	0051287	molecular_function	NAD binding
J	0006006	biological_process	glucose metabolic process
J	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
J	0050661	molecular_function	NADP binding
J	0051287	molecular_function	NAD binding
K	0006006	biological_process	glucose metabolic process
K	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
K	0050661	molecular_function	NADP binding
K	0051287	molecular_function	NAD binding
L	0006006	biological_process	glucose metabolic process
L	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
L	0050661	molecular_function	NADP binding
L	0051287	molecular_function	NAD binding
O	0006006	biological_process	glucose metabolic process
O	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
O	0050661	molecular_function	NADP binding
O	0051287	molecular_function	NAD binding
P	0006006	biological_process	glucose metabolic process
P	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
P	0050661	molecular_function	NADP binding
P	0051287	molecular_function	NAD binding
Q	0006006	biological_process	glucose metabolic process
Q	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Q	0050661	molecular_function	NADP binding
Q	0051287	molecular_function	NAD binding
R	0006006	biological_process	glucose metabolic process
R	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
R	0050661	molecular_function	NADP binding
R	0051287	molecular_function	NAD binding

Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
I	ALA147-LEU154
J	ALA150-LEU157

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Nucleophile

Chain	Residue	Details
J	CYS152
L	CYS152
B	CYS152
D	CYS152
R	CYS152
P	CYS152
H	CYS152
F	CYS152

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	BINDING: BINDING => ECO:0000269|PubMed:11846565, ECO:0000269|PubMed:12705826, ECO:0000269|PubMed:15236965, ECO:0000269|PubMed:17573533

Chain	Residue	Details
J	ARG10
J	ASP34
J	ARG79
J	ASN315
L	ARG10
L	ASP34
L	ARG79
L	ASN315
B	ARG10
B	ASP34
B	ARG79
B	ASN315
D	ARG10
D	ASP34
D	ARG79
D	ASN315
R	ARG10
R	ASP34
R	ARG79
R	ASN315
P	ARG10
P	ASP34
P	ARG79
P	ASN315
H	ARG10
H	ASP34
H	ARG79
H	ASN315
F	ARG10
F	ASP34
F	ARG79
F	ASN315

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
J	SER151
J	THR182
J	ARG197
J	THR210
J	ARG233
L	SER151
L	THR182
L	ARG197
L	THR210
L	ARG233
B	SER151
B	THR182
B	ARG197
B	THR210
B	ARG233
D	SER151
D	THR182
D	ARG197
D	THR210
D	ARG233
R	SER151
R	THR182
R	ARG197
R	THR210
R	ARG233
P	SER151
P	THR182
P	ARG197
P	THR210
P	ARG233
H	SER151
H	THR182
H	ARG197
H	THR210
H	ARG233
F	SER151
F	THR182
F	ARG197
F	THR210
F	ARG233

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	SITE: Activates thiol group during catalysis => ECO:0000250

Chain	Residue	Details
J	HIS179
L	HIS179
B	HIS179
D	HIS179
R	HIS179
P	HIS179
H	HIS179
F	HIS179

---