7PZZ

Crystal structure of serine hydroxymethyltransferase, isoform 2 from Arabidopsis thaliana (SHM2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004372	molecular_function	glycine hydroxymethyltransferase activity
A	0005739	cellular_component	mitochondrion
A	0006544	biological_process	glycine metabolic process
A	0006563	biological_process	L-serine metabolic process
A	0006730	biological_process	one-carbon metabolic process
A	0008270	molecular_function	zinc ion binding
A	0009507	cellular_component	chloroplast
A	0009536	cellular_component	plastid
A	0016740	molecular_function	transferase activity
A	0019264	biological_process	glycine biosynthetic process from serine
A	0030170	molecular_function	pyridoxal phosphate binding
A	0035999	biological_process	tetrahydrofolate interconversion
A	0045271	cellular_component	respiratory chain complex I
A	0046653	biological_process	tetrahydrofolate metabolic process
A	0050897	molecular_function	cobalt ion binding
B	0004372	molecular_function	glycine hydroxymethyltransferase activity
B	0005739	cellular_component	mitochondrion
B	0006544	biological_process	glycine metabolic process
B	0006563	biological_process	L-serine metabolic process
B	0006730	biological_process	one-carbon metabolic process
B	0008270	molecular_function	zinc ion binding
B	0009507	cellular_component	chloroplast
B	0009536	cellular_component	plastid
B	0016740	molecular_function	transferase activity
B	0019264	biological_process	glycine biosynthetic process from serine
B	0030170	molecular_function	pyridoxal phosphate binding
B	0035999	biological_process	tetrahydrofolate interconversion
B	0045271	cellular_component	respiratory chain complex I
B	0046653	biological_process	tetrahydrofolate metabolic process
B	0050897	molecular_function	cobalt ion binding
C	0004372	molecular_function	glycine hydroxymethyltransferase activity
C	0005739	cellular_component	mitochondrion
C	0006544	biological_process	glycine metabolic process
C	0006563	biological_process	L-serine metabolic process
C	0006730	biological_process	one-carbon metabolic process
C	0008270	molecular_function	zinc ion binding
C	0009507	cellular_component	chloroplast
C	0009536	cellular_component	plastid
C	0016740	molecular_function	transferase activity
C	0019264	biological_process	glycine biosynthetic process from serine
C	0030170	molecular_function	pyridoxal phosphate binding
C	0035999	biological_process	tetrahydrofolate interconversion
C	0045271	cellular_component	respiratory chain complex I
C	0046653	biological_process	tetrahydrofolate metabolic process
C	0050897	molecular_function	cobalt ion binding
D	0004372	molecular_function	glycine hydroxymethyltransferase activity
D	0005739	cellular_component	mitochondrion
D	0006544	biological_process	glycine metabolic process
D	0006563	biological_process	L-serine metabolic process
D	0006730	biological_process	one-carbon metabolic process
D	0008270	molecular_function	zinc ion binding
D	0009507	cellular_component	chloroplast
D	0009536	cellular_component	plastid
D	0016740	molecular_function	transferase activity
D	0019264	biological_process	glycine biosynthetic process from serine
D	0030170	molecular_function	pyridoxal phosphate binding
D	0035999	biological_process	tetrahydrofolate interconversion
D	0045271	cellular_component	respiratory chain complex I
D	0046653	biological_process	tetrahydrofolate metabolic process
D	0050897	molecular_function	cobalt ion binding

Functional Information from PROSITE/UniProt

site_id	PS00096
Number of Residues	17
Details	SHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DVvTTTTHKSLrGPRGA

Chain	Residue	Details
A	ASP278-ALA294

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31873125","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SMN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6SMW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31873125","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SMN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31873125","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SMW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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