7PZU
LpxC Inhibitors With Fluoroproline As A Novel Zinc-Binding Group Can Serve As A Novel Class of Antibiotic With Activity Against Multidrug-Resistant Gram-Negative Bacteria
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006796 | biological_process | phosphate-containing compound metabolic process |
A | 0009245 | biological_process | lipid A biosynthetic process |
A | 0016020 | cellular_component | membrane |
A | 0016787 | molecular_function | hydrolase activity |
A | 0019637 | biological_process | organophosphate metabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0103117 | molecular_function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity |
A | 1901135 | biological_process | carbohydrate derivative metabolic process |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00388 |
Chain | Residue | Details |
A | HIS264 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00388 |
Chain | Residue | Details |
A | HIS78 | |
A | HIS237 | |
A | ASP241 |