7PYT

Benzoylsuccinyl-CoA thiolase with coenzyme A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0046872	molecular_function	metal ion binding
B	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0046872	molecular_function	metal ion binding
D	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Acyl-thioester intermediate => ECO:0000250|UniProtKB:P42765

Chain	Residue	Details
B	CYS85
D	CYS85
A	CYS55
A	CYS58
C	CYS42
C	CYS45
C	CYS55
C	CYS58

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site_id	SWS_FT_FI2
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:35313080, ECO:0007744|PDB:7PYT, ECO:0007744|PDB:7YXM

Chain	Residue	Details
B	LYS19
D	CYS206
B	GLY122
B	ARG194
B	CYS205
B	CYS206
D	LYS19
D	GLY122
D	ARG194
D	CYS205

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:35313080, ECO:0007744|PDB:7YXM

Chain	Residue	Details
B	SER121
D	SER121

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site_id	SWS_FT_FI4
Number of Residues	2
Details	SITE: Increases nucleophilicity of active site Cys => ECO:0000250|UniProtKB:P42765

Chain	Residue	Details
B	HIS331
D	HIS331

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