7PUS

ERK5 in complex with Pyrrole Carboxamide scaffold

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0004672	molecular_function	protein kinase activity
AAA	0004707	molecular_function	MAP kinase activity
AAA	0005524	molecular_function	ATP binding
AAA	0006468	biological_process	protein phosphorylation

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	25
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGNGAYGVVSsArrrltgqqv.........AIKK

Chain	Residue	Details
AAA	ILE61-LYS85

---

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ViHrDLKpsNLLV

Chain	Residue	Details
AAA	VAL178-VAL190

---

site_id	PS01351
Number of Residues	105
Details	MAPK MAP kinase signature. FdvvtnakrtlRElkilkhfkhdniiaikdilrptvpygefksvyvvldlmesdlhqiihssqpltlehvryflyqllrglkymhsaqvih........RDlKpsnllvnenC

Chain	Residue	Details
AAA	PHE90-CYS194

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027

Chain	Residue	Details
AAA	ASP182

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
AAA	ILE61
AAA	LYS84

---