7PTH

C54S mutant of choline-sulfatase from E. meliloti CECT4857 bound to choline

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008484	molecular_function	sulfuric ester hydrolase activity
A	0016787	molecular_function	hydrolase activity
A	0042425	biological_process	choline biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0047753	molecular_function	choline-sulfatase activity
B	0005737	cellular_component	cytoplasm
B	0008484	molecular_function	sulfuric ester hydrolase activity
B	0016787	molecular_function	hydrolase activity
B	0042425	biological_process	choline biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0047753	molecular_function	choline-sulfatase activity
C	0005737	cellular_component	cytoplasm
C	0008484	molecular_function	sulfuric ester hydrolase activity
C	0016787	molecular_function	hydrolase activity
C	0042425	biological_process	choline biosynthetic process
C	0046872	molecular_function	metal ion binding
C	0047753	molecular_function	choline-sulfatase activity
D	0005737	cellular_component	cytoplasm
D	0008484	molecular_function	sulfuric ester hydrolase activity
D	0016787	molecular_function	hydrolase activity
D	0042425	biological_process	choline biosynthetic process
D	0046872	molecular_function	metal ion binding
D	0047753	molecular_function	choline-sulfatase activity

Functional Information from PROSITE/UniProt

site_id	PS00149
Number of Residues	11
Details	SULFATASE_2 Sulfatases signature 2. GYyTalSGK.MH

Chain	Residue	Details
A	GLY94-HIS104

---

site_id	PS00523
Number of Residues	13
Details	SULFATASE_1 Sulfatases signature 1. PLSAPARasFMAG

Chain	Residue	Details
A	PRO52-GLY64

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"P15289","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P15289","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	16
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"description":"via 3-oxoalanine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"3-oxoalanine (Cys)","evidences":[{"source":"UniProtKB","id":"P15289","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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