7PP8

STRUCTURE OF ESTER-HYDROLASE EH7 FROM METAGENOME OF MARINE SEDIMENTS AT MILAZZO HARBOR (SICILY, ITALY) COMPLEXED WITH A DERIVATIVE OF METHYL 4-NITROPHENYL HEXYLPHOSPHONATE

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MHH A 501

Chain	Residue
A	TYR75
A	SER76
A	TYR192
A	GLY365
A	MET366

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site_id	AC2
Number of Residues	2
Details	binding site for residue GOL C 501

Chain	Residue
C	VAL49
C	ARG68

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site_id	AC3
Number of Residues	2
Details	binding site for residue GOL C 502

Chain	Residue
C	GLN204
C	GLY208

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site_id	AC4
Number of Residues	2
Details	binding site for residue GOL C 503

Chain	Residue
C	HIS32
H	ASP171

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site_id	AC5
Number of Residues	10
Details	binding site for residue PEG C 504

Chain	Residue
C	SER344
C	LYS346
C	GLU360
C	TYR361
C	GLY362
C	TRP363
C	ASN370
C	PHE371
C	PHE372
C	ARG400

---

site_id	AC6
Number of Residues	4
Details	binding site for residue GOL D 501

Chain	Residue
D	PRO333
D	TYR334
D	ARG396
D	GLN397

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site_id	AC7
Number of Residues	2
Details	binding site for residue GOL D 502

Chain	Residue
D	THR107
G	HIS32

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site_id	AC8
Number of Residues	3
Details	binding site for residue GOL D 503

Chain	Residue
D	ALA266
F	ASN9
F	ILE10

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site_id	AC9
Number of Residues	11
Details	binding site for Di-peptide MHH B 501 and SER B 77

Chain	Residue
B	ILE74
B	TYR75
B	MET77
B	THR78
B	LYS79
B	TYR192
B	GLY273
B	TRP363
B	GLY364
B	GLY365
B	MET366

---

site_id	AD1
Number of Residues	11
Details	binding site for Di-peptide MHH C 505 and SER C 77

Chain	Residue
C	ILE74
C	TYR75
C	MET77
C	THR78
C	LYS79
C	TYR192
C	GLY273
C	TRP363
C	GLY364
C	GLY365
C	MET366

---

site_id	AD2
Number of Residues	13
Details	binding site for Di-peptide MHH D 504 and SER D 77

Chain	Residue
D	ILE74
D	TYR75
D	MET77
D	THR78
D	LYS79
D	TYR145
D	PHE147
D	TYR192
D	GLY273
D	TRP363
D	GLY364
D	GLY365
D	MET366

---

site_id	AD3
Number of Residues	11
Details	binding site for Di-peptide MHH E 501 and SER E 77

Chain	Residue
E	ILE74
E	TYR75
E	MET77
E	THR78
E	LYS79
E	TYR192
E	GLY273
E	TRP363
E	GLY364
E	GLY365
E	MET366

---

site_id	AD4
Number of Residues	11
Details	binding site for Di-peptide MHH F 501 and SER F 77

Chain	Residue
F	ILE74
F	TYR75
F	MET77
F	THR78
F	LYS79
F	TYR192
F	GLY273
F	TRP363
F	GLY364
F	GLY365
F	MET366

---

site_id	AD5
Number of Residues	12
Details	binding site for Di-peptide MHH G 501 and SER G 77

Chain	Residue
G	ILE74
G	TYR75
G	MET77
G	THR78
G	LYS79
G	ASP163
G	TYR192
G	GLY273
G	TRP363
G	GLY364
G	GLY365
G	MET366

---

site_id	AD6
Number of Residues	11
Details	binding site for Di-peptide MHH H 501 and SER H 77

Chain	Residue
H	ILE74
H	TYR75
H	MET77
H	THR78
H	LYS79
H	TYR192
H	GLY273
H	TRP363
H	GLY364
H	GLY365
H	MET366

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