Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7PO7

Phosphoglycolate phosphatase from Mus musculus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000121	molecular_function	glycerol-1-phosphatase activity
A	0000287	molecular_function	magnesium ion binding
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
A	0006114	biological_process	glycerol biosynthetic process
A	0006338	biological_process	chromatin remodeling
A	0006650	biological_process	glycerophospholipid metabolic process
A	0008967	molecular_function	phosphoglycolate phosphatase activity
A	0016791	molecular_function	phosphatase activity
A	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
A	0043136	molecular_function	glycerol-3-phosphatase activity
A	0043262	molecular_function	ADP phosphatase activity
A	0045721	biological_process	negative regulation of gluconeogenesis
A	0046872	molecular_function	metal ion binding
A	0140793	molecular_function	histone H2AXY142 phosphatase activity
B	0000121	molecular_function	glycerol-1-phosphatase activity
B	0000287	molecular_function	magnesium ion binding
B	0004721	molecular_function	phosphoprotein phosphatase activity
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
B	0006114	biological_process	glycerol biosynthetic process
B	0006338	biological_process	chromatin remodeling
B	0006650	biological_process	glycerophospholipid metabolic process
B	0008967	molecular_function	phosphoglycolate phosphatase activity
B	0016791	molecular_function	phosphatase activity
B	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
B	0043136	molecular_function	glycerol-3-phosphatase activity
B	0043262	molecular_function	ADP phosphatase activity
B	0045721	biological_process	negative regulation of gluconeogenesis
B	0046872	molecular_function	metal ion binding
B	0140793	molecular_function	histone H2AXY142 phosphatase activity
C	0000121	molecular_function	glycerol-1-phosphatase activity
C	0000287	molecular_function	magnesium ion binding
C	0004721	molecular_function	phosphoprotein phosphatase activity
C	0004725	molecular_function	protein tyrosine phosphatase activity
C	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
C	0006114	biological_process	glycerol biosynthetic process
C	0006338	biological_process	chromatin remodeling
C	0006650	biological_process	glycerophospholipid metabolic process
C	0008967	molecular_function	phosphoglycolate phosphatase activity
C	0016791	molecular_function	phosphatase activity
C	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
C	0043136	molecular_function	glycerol-3-phosphatase activity
C	0043262	molecular_function	ADP phosphatase activity
C	0045721	biological_process	negative regulation of gluconeogenesis
C	0046872	molecular_function	metal ion binding
C	0140793	molecular_function	histone H2AXY142 phosphatase activity
D	0000121	molecular_function	glycerol-1-phosphatase activity
D	0000287	molecular_function	magnesium ion binding
D	0004721	molecular_function	phosphoprotein phosphatase activity
D	0004725	molecular_function	protein tyrosine phosphatase activity
D	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
D	0006114	biological_process	glycerol biosynthetic process
D	0006338	biological_process	chromatin remodeling
D	0006650	biological_process	glycerophospholipid metabolic process
D	0008967	molecular_function	phosphoglycolate phosphatase activity
D	0016791	molecular_function	phosphatase activity
D	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
D	0043136	molecular_function	glycerol-3-phosphatase activity
D	0043262	molecular_function	ADP phosphatase activity
D	0045721	biological_process	negative regulation of gluconeogenesis
D	0046872	molecular_function	metal ion binding
D	0140793	molecular_function	histone H2AXY142 phosphatase activity
E	0000121	molecular_function	glycerol-1-phosphatase activity
E	0000287	molecular_function	magnesium ion binding
E	0004721	molecular_function	phosphoprotein phosphatase activity
E	0004725	molecular_function	protein tyrosine phosphatase activity
E	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
E	0006114	biological_process	glycerol biosynthetic process
E	0006338	biological_process	chromatin remodeling
E	0006650	biological_process	glycerophospholipid metabolic process
E	0008967	molecular_function	phosphoglycolate phosphatase activity
E	0016791	molecular_function	phosphatase activity
E	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
E	0043136	molecular_function	glycerol-3-phosphatase activity
E	0043262	molecular_function	ADP phosphatase activity
E	0045721	biological_process	negative regulation of gluconeogenesis
E	0046872	molecular_function	metal ion binding
E	0140793	molecular_function	histone H2AXY142 phosphatase activity
F	0000121	molecular_function	glycerol-1-phosphatase activity
F	0000287	molecular_function	magnesium ion binding
F	0004721	molecular_function	phosphoprotein phosphatase activity
F	0004725	molecular_function	protein tyrosine phosphatase activity
F	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
F	0006114	biological_process	glycerol biosynthetic process
F	0006338	biological_process	chromatin remodeling
F	0006650	biological_process	glycerophospholipid metabolic process
F	0008967	molecular_function	phosphoglycolate phosphatase activity
F	0016791	molecular_function	phosphatase activity
F	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
F	0043136	molecular_function	glycerol-3-phosphatase activity
F	0043262	molecular_function	ADP phosphatase activity
F	0045721	biological_process	negative regulation of gluconeogenesis
F	0046872	molecular_function	metal ion binding
F	0140793	molecular_function	histone H2AXY142 phosphatase activity
G	0000121	molecular_function	glycerol-1-phosphatase activity
G	0000287	molecular_function	magnesium ion binding
G	0004721	molecular_function	phosphoprotein phosphatase activity
G	0004725	molecular_function	protein tyrosine phosphatase activity
G	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
G	0006114	biological_process	glycerol biosynthetic process
G	0006338	biological_process	chromatin remodeling
G	0006650	biological_process	glycerophospholipid metabolic process
G	0008967	molecular_function	phosphoglycolate phosphatase activity
G	0016791	molecular_function	phosphatase activity
G	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
G	0043136	molecular_function	glycerol-3-phosphatase activity
G	0043262	molecular_function	ADP phosphatase activity
G	0045721	biological_process	negative regulation of gluconeogenesis
G	0046872	molecular_function	metal ion binding
G	0140793	molecular_function	histone H2AXY142 phosphatase activity
H	0000121	molecular_function	glycerol-1-phosphatase activity
H	0000287	molecular_function	magnesium ion binding
H	0004721	molecular_function	phosphoprotein phosphatase activity
H	0004725	molecular_function	protein tyrosine phosphatase activity
H	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
H	0006114	biological_process	glycerol biosynthetic process
H	0006338	biological_process	chromatin remodeling
H	0006650	biological_process	glycerophospholipid metabolic process
H	0008967	molecular_function	phosphoglycolate phosphatase activity
H	0016791	molecular_function	phosphatase activity
H	0030946	molecular_function	protein tyrosine phosphatase activity, metal-dependent
H	0043136	molecular_function	glycerol-3-phosphatase activity
H	0043262	molecular_function	ADP phosphatase activity
H	0045721	biological_process	negative regulation of gluconeogenesis
H	0046872	molecular_function	metal ion binding
H	0140793	molecular_function	histone H2AXY142 phosphatase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Nucleophile => ECO:0000269\|PubMed:24338473

Chain	Residue	Details
A	ASN34
B	ASN34
C	ASN34
D	ASN34
E	ASN34
F	ASN34
G	ASN34
H	ASN34

site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Proton donor => ECO:0000305

Chain	Residue	Details
A	ASP36
B	ASP36
C	ASP36
D	ASP36
E	ASP36
F	ASP36
G	ASP36
H	ASP36

site_id	SWS_FT_FI3
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P60487

Chain	Residue	Details
A	ASN34
D	ASN34
D	ASP36
D	ASP260
E	ASN34
E	ASP36
E	ASP260
F	ASN34
F	ASP36
F	ASP260
G	ASN34
A	ASP36
G	ASP36
G	ASP260
H	ASN34
H	ASP36
H	ASP260
A	ASP260
B	ASN34
B	ASP36
B	ASP260
C	ASN34
C	ASP36
C	ASP260

site_id	SWS_FT_FI4
Number of Residues	8
Details	SITE: Important for substrate specificity => ECO:0000305\|PubMed:24338473

Chain	Residue	Details
A	LEU204
B	LEU204
C	LEU204
D	LEU204
E	LEU204
F	LEU204
G	LEU204
H	LEU204

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)