7PO2

Initiation complex of human mitochondrial ribosome small subunit with IF2, fMet-tRNAMet and mRNA

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003735	molecular_function	structural constituent of ribosome
0	0005739	cellular_component	mitochondrion
0	0005743	cellular_component	mitochondrial inner membrane
0	0005763	cellular_component	mitochondrial small ribosomal subunit
0	0005840	cellular_component	ribosome
0	0032543	biological_process	mitochondrial translation
0	1990904	cellular_component	ribonucleoprotein complex
1	0003723	molecular_function	RNA binding
1	0003735	molecular_function	structural constituent of ribosome
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0005763	cellular_component	mitochondrial small ribosomal subunit
1	0005840	cellular_component	ribosome
1	0032543	biological_process	mitochondrial translation
1	1990904	cellular_component	ribonucleoprotein complex
2	0001650	cellular_component	fibrillar center
2	0003723	molecular_function	RNA binding
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005654	cellular_component	nucleoplasm
2	0005739	cellular_component	mitochondrion
2	0005743	cellular_component	mitochondrial inner membrane
2	0005761	cellular_component	mitochondrial ribosome
2	0005763	cellular_component	mitochondrial small ribosomal subunit
2	0005829	cellular_component	cytosol
2	0005840	cellular_component	ribosome
2	0032543	biological_process	mitochondrial translation
2	1990904	cellular_component	ribonucleoprotein complex
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005654	cellular_component	nucleoplasm
3	0005739	cellular_component	mitochondrion
3	0005743	cellular_component	mitochondrial inner membrane
3	0005759	cellular_component	mitochondrial matrix
3	0005763	cellular_component	mitochondrial small ribosomal subunit
3	0005840	cellular_component	ribosome
3	0032543	biological_process	mitochondrial translation
3	0043231	cellular_component	intracellular membrane-bounded organelle
3	0045839	biological_process	negative regulation of mitotic nuclear division
3	0045862	biological_process	positive regulation of proteolysis
3	1990904	cellular_component	ribonucleoprotein complex
4	0003723	molecular_function	RNA binding
4	0005515	molecular_function	protein binding
4	0005654	cellular_component	nucleoplasm
4	0005739	cellular_component	mitochondrion
4	0005743	cellular_component	mitochondrial inner membrane
4	0005763	cellular_component	mitochondrial small ribosomal subunit
4	0005829	cellular_component	cytosol
4	0005840	cellular_component	ribosome
4	0005886	cellular_component	plasma membrane
4	0006417	biological_process	regulation of translation
4	0019843	molecular_function	rRNA binding
4	0032543	biological_process	mitochondrial translation
4	0043024	molecular_function	ribosomal small subunit binding
4	1990904	cellular_component	ribonucleoprotein complex
7	0003723	molecular_function	RNA binding
7	0003743	molecular_function	translation initiation factor activity
7	0003924	molecular_function	GTPase activity
7	0005525	molecular_function	GTP binding
7	0005654	cellular_component	nucleoplasm
7	0005737	cellular_component	cytoplasm
7	0005739	cellular_component	mitochondrion
7	0006412	biological_process	translation
7	0006413	biological_process	translational initiation
7	0006446	biological_process	regulation of translational initiation
7	0008135	molecular_function	translation factor activity, RNA binding
7	0032790	biological_process	ribosome disassembly
7	0043024	molecular_function	ribosomal small subunit binding
7	0070124	biological_process	mitochondrial translational initiation
B	0003735	molecular_function	structural constituent of ribosome
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0005759	cellular_component	mitochondrial matrix
B	0005763	cellular_component	mitochondrial small ribosomal subunit
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0015935	cellular_component	small ribosomal subunit
B	0032543	biological_process	mitochondrial translation
B	0061668	biological_process	mitochondrial ribosome assembly
B	1990904	cellular_component	ribonucleoprotein complex
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005763	cellular_component	mitochondrial small ribosomal subunit
C	0005840	cellular_component	ribosome
C	0008150	biological_process	biological_process
C	0032543	biological_process	mitochondrial translation
C	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005763	cellular_component	mitochondrial small ribosomal subunit
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0032543	biological_process	mitochondrial translation
D	0043229	cellular_component	intracellular organelle
D	1990904	cellular_component	ribonucleoprotein complex
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005763	cellular_component	mitochondrial small ribosomal subunit
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
E	0019843	molecular_function	rRNA binding
E	0032543	biological_process	mitochondrial translation
E	0043229	cellular_component	intracellular organelle
E	0070181	molecular_function	small ribosomal subunit rRNA binding
E	1990904	cellular_component	ribonucleoprotein complex
F	0000028	biological_process	ribosomal small subunit assembly
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005763	cellular_component	mitochondrial small ribosomal subunit
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
F	0032543	biological_process	mitochondrial translation
F	1990904	cellular_component	ribonucleoprotein complex
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005730	cellular_component	nucleolus
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005763	cellular_component	mitochondrial small ribosomal subunit
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0032543	biological_process	mitochondrial translation
G	0043232	cellular_component	intracellular non-membrane-bounded organelle
G	1990904	cellular_component	ribonucleoprotein complex
H	0003674	molecular_function	molecular_function
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005759	cellular_component	mitochondrial matrix
H	0005763	cellular_component	mitochondrial small ribosomal subunit
H	0005840	cellular_component	ribosome
H	0008150	biological_process	biological_process
H	0032543	biological_process	mitochondrial translation
H	1990904	cellular_component	ribonucleoprotein complex
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005763	cellular_component	mitochondrial small ribosomal subunit
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0032543	biological_process	mitochondrial translation
I	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0005761	cellular_component	mitochondrial ribosome
J	0005763	cellular_component	mitochondrial small ribosomal subunit
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	0032543	biological_process	mitochondrial translation
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005761	cellular_component	mitochondrial ribosome
K	0005763	cellular_component	mitochondrial small ribosomal subunit
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0031965	cellular_component	nuclear membrane
K	0032543	biological_process	mitochondrial translation
K	0043229	cellular_component	intracellular organelle
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005654	cellular_component	nucleoplasm
L	0005730	cellular_component	nucleolus
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005759	cellular_component	mitochondrial matrix
L	0005761	cellular_component	mitochondrial ribosome
L	0005763	cellular_component	mitochondrial small ribosomal subunit
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0032543	biological_process	mitochondrial translation
L	0043229	cellular_component	intracellular organelle
L	1990904	cellular_component	ribonucleoprotein complex
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005763	cellular_component	mitochondrial small ribosomal subunit
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0032543	biological_process	mitochondrial translation
M	0043229	cellular_component	intracellular organelle
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005763	cellular_component	mitochondrial small ribosomal subunit
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0019843	molecular_function	rRNA binding
N	0032543	biological_process	mitochondrial translation
N	1990904	cellular_component	ribonucleoprotein complex
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005654	cellular_component	nucleoplasm
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005763	cellular_component	mitochondrial small ribosomal subunit
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0030054	cellular_component	cell junction
O	0032543	biological_process	mitochondrial translation
O	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005763	cellular_component	mitochondrial small ribosomal subunit
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0032543	biological_process	mitochondrial translation
P	0070181	molecular_function	small ribosomal subunit rRNA binding
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005763	cellular_component	mitochondrial small ribosomal subunit
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0032543	biological_process	mitochondrial translation
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003735	molecular_function	structural constituent of ribosome
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005761	cellular_component	mitochondrial ribosome
R	0005763	cellular_component	mitochondrial small ribosomal subunit
R	0005840	cellular_component	ribosome
R	0008150	biological_process	biological_process
R	0032543	biological_process	mitochondrial translation
R	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005763	cellular_component	mitochondrial small ribosomal subunit
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0031965	cellular_component	nuclear membrane
S	0032543	biological_process	mitochondrial translation
S	1990904	cellular_component	ribonucleoprotein complex
t	0003723	molecular_function	RNA binding
t	0003729	molecular_function	mRNA binding
t	0003735	molecular_function	structural constituent of ribosome
t	0005515	molecular_function	protein binding
t	0005737	cellular_component	cytoplasm
t	0005739	cellular_component	mitochondrion
t	0005743	cellular_component	mitochondrial inner membrane
t	0005759	cellular_component	mitochondrial matrix
t	0005762	cellular_component	mitochondrial large ribosomal subunit
t	0005840	cellular_component	ribosome
t	0006390	biological_process	mitochondrial transcription
t	0006412	biological_process	translation
t	0032543	biological_process	mitochondrial translation
t	0045893	biological_process	positive regulation of DNA-templated transcription
t	1990904	cellular_component	ribonucleoprotein complex
T	0003735	molecular_function	structural constituent of ribosome
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0005763	cellular_component	mitochondrial small ribosomal subunit
T	0005840	cellular_component	ribosome
T	0032543	biological_process	mitochondrial translation
T	1990904	cellular_component	ribonucleoprotein complex
U	0003723	molecular_function	RNA binding
U	0005654	cellular_component	nucleoplasm
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0005763	cellular_component	mitochondrial small ribosomal subunit
U	0005840	cellular_component	ribosome
U	0032543	biological_process	mitochondrial translation
U	1990904	cellular_component	ribonucleoprotein complex
V	0000049	molecular_function	tRNA binding
V	0005515	molecular_function	protein binding
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0005763	cellular_component	mitochondrial small ribosomal subunit
V	0005840	cellular_component	ribosome
V	0006417	biological_process	regulation of translation
V	0008283	biological_process	cell population proliferation
V	0019843	molecular_function	rRNA binding
V	0032543	biological_process	mitochondrial translation
V	0070131	biological_process	positive regulation of mitochondrial translation
V	0097177	molecular_function	mitochondrial ribosome binding
V	1990904	cellular_component	ribonucleoprotein complex
W	0003723	molecular_function	RNA binding
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0005763	cellular_component	mitochondrial small ribosomal subunit
W	0005840	cellular_component	ribosome
W	0032543	biological_process	mitochondrial translation
W	1990904	cellular_component	ribonucleoprotein complex
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005525	molecular_function	GTP binding
X	0005654	cellular_component	nucleoplasm
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005761	cellular_component	mitochondrial ribosome
X	0005763	cellular_component	mitochondrial small ribosomal subunit
X	0005840	cellular_component	ribosome
X	0006915	biological_process	apoptotic process
X	0015935	cellular_component	small ribosomal subunit
X	0032543	biological_process	mitochondrial translation
X	0097190	biological_process	apoptotic signaling pathway
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005515	molecular_function	protein binding
Y	0005730	cellular_component	nucleolus
Y	0005739	cellular_component	mitochondrion
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005763	cellular_component	mitochondrial small ribosomal subunit
Y	0005840	cellular_component	ribosome
Y	0019904	molecular_function	protein domain specific binding
Y	0032543	biological_process	mitochondrial translation
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005763	cellular_component	mitochondrial small ribosomal subunit
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0032543	biological_process	mitochondrial translation
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAnR

Chain	Residue	Details
J	LYS71-ARG78

---

site_id	PS00057
Number of Residues	25
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. VDYkn.VqlLsqFVSPftGCIygrHI

Chain	Residue	Details
P	VAL72-ILE96

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGrsAQagAirlAmAKAL

Chain	Residue	Details
G	GLY334-LEU352

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRkksIrVlvAVGNgk.GaAGfSigkat.DRmd.AF

Chain	Residue	Details
D	GLY236-PHE268

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VrSLFDARVHLG

Chain	Residue	Details
B	VAL81-GLY92

---

site_id	PS01176
Number of Residues	23
Details	IF2 Initiation factor 2 signature. GsLtsLKHhKddisiVktGmDCG

Chain	Residue	Details
7	GLY671-GLY693

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
G	LYS287
F	LYS228
7	ASN288

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q9DB15

Chain	Residue	Details
t	LYS150
t	LYS162
t	LYS178

---