7PMZ

Crystal structure of Streptomyces coelicolor guaB (IMP dehydrogenase) bound to ATP and ppGpp at 2.0 A resolution

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0003938	molecular_function	IMP dehydrogenase activity
A	0005524	molecular_function	ATP binding
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006177	biological_process	GMP biosynthetic process
A	0006183	biological_process	GTP biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0003824	molecular_function	catalytic activity
B	0003938	molecular_function	IMP dehydrogenase activity
B	0005524	molecular_function	ATP binding
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0006177	biological_process	GMP biosynthetic process
B	0006183	biological_process	GTP biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0003938	molecular_function	IMP dehydrogenase activity
C	0005524	molecular_function	ATP binding
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0006177	biological_process	GMP biosynthetic process
C	0006183	biological_process	GTP biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0003938	molecular_function	IMP dehydrogenase activity
D	0005524	molecular_function	ATP binding
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0006177	biological_process	GMP biosynthetic process
D	0006183	biological_process	GTP biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0003824	molecular_function	catalytic activity
E	0003938	molecular_function	IMP dehydrogenase activity
E	0005524	molecular_function	ATP binding
E	0006164	biological_process	purine nucleotide biosynthetic process
E	0006177	biological_process	GMP biosynthetic process
E	0006183	biological_process	GTP biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0003824	molecular_function	catalytic activity
F	0003938	molecular_function	IMP dehydrogenase activity
F	0005524	molecular_function	ATP binding
F	0006164	biological_process	purine nucleotide biosynthetic process
F	0006177	biological_process	GMP biosynthetic process
F	0006183	biological_process	GTP biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0003824	molecular_function	catalytic activity
G	0003938	molecular_function	IMP dehydrogenase activity
G	0005524	molecular_function	ATP binding
G	0006164	biological_process	purine nucleotide biosynthetic process
G	0006177	biological_process	GMP biosynthetic process
G	0006183	biological_process	GTP biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0003824	molecular_function	catalytic activity
H	0003938	molecular_function	IMP dehydrogenase activity
H	0005524	molecular_function	ATP binding
H	0006164	biological_process	purine nucleotide biosynthetic process
H	0006177	biological_process	GMP biosynthetic process
H	0006183	biological_process	GTP biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0046872	molecular_function	metal ion binding
I	0000166	molecular_function	nucleotide binding
I	0003824	molecular_function	catalytic activity
I	0003938	molecular_function	IMP dehydrogenase activity
I	0005524	molecular_function	ATP binding
I	0006164	biological_process	purine nucleotide biosynthetic process
I	0006177	biological_process	GMP biosynthetic process
I	0006183	biological_process	GTP biosynthetic process
I	0016491	molecular_function	oxidoreductase activity
I	0046872	molecular_function	metal ion binding
J	0000166	molecular_function	nucleotide binding
J	0003824	molecular_function	catalytic activity
J	0003938	molecular_function	IMP dehydrogenase activity
J	0005524	molecular_function	ATP binding
J	0006164	biological_process	purine nucleotide biosynthetic process
J	0006177	biological_process	GMP biosynthetic process
J	0006183	biological_process	GTP biosynthetic process
J	0016491	molecular_function	oxidoreductase activity
J	0046872	molecular_function	metal ion binding
K	0000166	molecular_function	nucleotide binding
K	0003824	molecular_function	catalytic activity
K	0003938	molecular_function	IMP dehydrogenase activity
K	0005524	molecular_function	ATP binding
K	0006164	biological_process	purine nucleotide biosynthetic process
K	0006177	biological_process	GMP biosynthetic process
K	0006183	biological_process	GTP biosynthetic process
K	0016491	molecular_function	oxidoreductase activity
K	0046872	molecular_function	metal ion binding
L	0000166	molecular_function	nucleotide binding
L	0003824	molecular_function	catalytic activity
L	0003938	molecular_function	IMP dehydrogenase activity
L	0005524	molecular_function	ATP binding
L	0006164	biological_process	purine nucleotide biosynthetic process
L	0006177	biological_process	GMP biosynthetic process
L	0006183	biological_process	GTP biosynthetic process
L	0016491	molecular_function	oxidoreductase activity
L	0046872	molecular_function	metal ion binding
M	0000166	molecular_function	nucleotide binding
M	0003824	molecular_function	catalytic activity
M	0003938	molecular_function	IMP dehydrogenase activity
M	0005524	molecular_function	ATP binding
M	0006164	biological_process	purine nucleotide biosynthetic process
M	0006177	biological_process	GMP biosynthetic process
M	0006183	biological_process	GTP biosynthetic process
M	0016491	molecular_function	oxidoreductase activity
M	0046872	molecular_function	metal ion binding
N	0000166	molecular_function	nucleotide binding
N	0003824	molecular_function	catalytic activity
N	0003938	molecular_function	IMP dehydrogenase activity
N	0005524	molecular_function	ATP binding
N	0006164	biological_process	purine nucleotide biosynthetic process
N	0006177	biological_process	GMP biosynthetic process
N	0006183	biological_process	GTP biosynthetic process
N	0016491	molecular_function	oxidoreductase activity
N	0046872	molecular_function	metal ion binding
O	0000166	molecular_function	nucleotide binding
O	0003824	molecular_function	catalytic activity
O	0003938	molecular_function	IMP dehydrogenase activity
O	0005524	molecular_function	ATP binding
O	0006164	biological_process	purine nucleotide biosynthetic process
O	0006177	biological_process	GMP biosynthetic process
O	0006183	biological_process	GTP biosynthetic process
O	0016491	molecular_function	oxidoreductase activity
O	0046872	molecular_function	metal ion binding
P	0000166	molecular_function	nucleotide binding
P	0003824	molecular_function	catalytic activity
P	0003938	molecular_function	IMP dehydrogenase activity
P	0005524	molecular_function	ATP binding
P	0006164	biological_process	purine nucleotide biosynthetic process
P	0006177	biological_process	GMP biosynthetic process
P	0006183	biological_process	GTP biosynthetic process
P	0016491	molecular_function	oxidoreductase activity
P	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00487
Number of Residues	13
Details	IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. IKVGVGpGSICtT

Chain	Residue	Details
A	ILE301-THR313

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